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2.
Nihon Shokakibyo Gakkai Zasshi ; 110(3): 432-40, 2013 Mar.
Article in Japanese | MEDLINE | ID: mdl-23459538

ABSTRACT

A 72-year-old man presented with consciousness disturbance. The results of brain magnetic resonance imaging and cerebrospinal fluid examination were normal, but triphasic waves were noted on electroencephalography. His plasma ammonia level was elevated due to which encephalopathy secondary to hyperammonemia was suspected. However, his liver function was normal, and no evidence of cirrhosis or portal-systemic shunt was noted. The patient's medical history revealed that he had a tendency to excessively consume pulse products since childhood, and an amino acid analysis showed elevation of citrulline and arginine levels. Thus, we diagnosed the patient with an extremely rare case of adult-onset type II citrullinemia, which was triggered by cessation of the intake of pulse foods (soybeans and peanuts) due to dental problems.


Subject(s)
Retinoschisis/diagnosis , Aged , Citrullinemia , Humans , Male
3.
Kansenshogaku Zasshi ; 82(2): 77-81, 2008 Mar.
Article in Japanese | MEDLINE | ID: mdl-18411764

ABSTRACT

A 77-year-old woman who have no past history, was admitted in a local hospital in Muroto City, Kochi, Japan, after several days of fever and severe general fatigue and generalized skin erythema. She was suspected to have Japanease spotted fever, which was a local pandemic disease. She was treated with minocycline immediately. The next day, she had consciousness disturbance and low blood pressure. Laboratory findings indicated disseminated intravascular coagulation (DIC) and multiple organ failure. She was referred to our hospital. An eschar was identified in the back of It. femur. Treatment included minocycline, ciprofloxain, gabexate mesilate, methylprednisolone, hemodialysis and mechanical ventilation. In spite of the avobe treatment, she died 3 days after admission of the local hospital. Though the serological test showed no positive antibody titer against Rickettsia japonica, Rickettsia japonica was isoleted from blood culture, to confirm Japanese spotted fever, Japanese spotted fever is generaly a curative disease with early diagnosis and minocycline. In this case, the patient died 3 days after proper diagnosis and treatment was started. We reported the second fatal Japanese spotted fever case in Japan.


Subject(s)
Rickettsia Infections/therapy , Aged , Anti-Bacterial Agents/administration & dosage , Ciprofloxacin/administration & dosage , Disseminated Intravascular Coagulation/etiology , Drug Therapy, Combination , Fatal Outcome , Female , Humans , Japan , Methylprednisolone/administration & dosage , Minocycline/administration & dosage , Multiple Organ Failure/etiology , Renal Dialysis , Respiration, Artificial , Rickettsia/isolation & purification , Rickettsia Infections/complications , Rickettsia Infections/diagnosis , Rickettsia Infections/microbiology , Severity of Illness Index
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