Pulmonary Artery Enlargement: An Independent Risk Factor for Mortality in Patients Hospitalized With COVID-19.

Objective: To assess whether baseline pulmonary artery diameter (PAD), obtained from noncontrast nongated computed tomography (NCCT), can be associated with coronavirus disease 2019 (COVID-19) outcomes. Patients and Methods: This is a retrospective study of patients hospitalized with COVID-19 admitted to Hôtel-Dieu de France university hospital (Beirut, Lebanon) between March 1, 2020 and March 1, 2021. Pulmonary artery diameter was measured at baseline NCCT. Various outcomes were assessed, including hospital length of stay, intensive care unit admission, invasive mechanical ventilation, mortality, and Post-COVID-19 Functional Status scale at discharge and at 2-month follow-up. Results: Four hundred sixty-five patients underwent baseline NCCT, including 315 men (67.7%) with a mean age of 63.7±16 years. Baseline PAD was higher in critically ill patients admitted to the intensive care unit (mean difference, 0.8 mm; 95% CI, 0.4-1.59 mm) and those receiving invasive mechanical ventilation (mean difference, 1.1 mm; 95% CI, 0.11-2.04 mm). Pulmonary artery diameter at baseline correlated significantly with hospital length of stay (r=0.130; P=.005), discharge status (r=0.117; P=.023), and with Post-COVID-19 Functional Status scale at 2-month follow-up (r=0.121; P=.021). Moreover, multivariable logistic regression showed that a PAD of 24.5 mm and above independently predicted in-hospital all-cause mortality remained unaffected in patients with COVID-19 (odds ratio, 2.07; 95% CI, 1.05-4.09). Conclusion: Baseline PAD measurement using NCCT can be a useful prognostic parameter. Its measurement can help to identify early severe cases and adapt the initial management of patients hospitalized with COVID-19.

A Way to Prеdict an Imminеnt Cardiac Arrеst on Abdominal CT Scan: About a Casе.

Imaging of a patiеnt undеrgoing cardiac arrеst is not common but thе abnormal hеmodynamics duе to thе pump failurе havе charactеristic imaging fеaturеs on CT-scan. Thе main imaging fеaturеs includе stasis and pooling of blood in thе dеpеndеnt organs of thе body, thе infеrior vеna cava, thе right rеnal vеin, thе right hеpatic vеin and thе right hеpatic parеnchyma. Knowlеdgе of thеsе signs is еssеntial in ordеr to start rеsuscitating thе patiеnt and can havе important survival implications. Wе rеport thе contrast-еnhancеd CT-scan fеaturеs of thе casе of a critically-ill patiеnt having imminеnt cardiac arrеst fеw minutеs aftеr thе еxamination.

Could contrast-enhanced CT detect STEMI prior to electrocardiogram?

We present here a case in which contrast-enhanced computed tomography (CT) was the first diagnostic tool to detect myocardial hypoperfusion in a patient with atypical symptoms and normal electrocardiogram (ECG) on admission. An ST-segment elevation was detected thereafter on a second ECG realized several minutes after CT with raised troponin levels. Percutaneous coronary intervention was performed after failure of thrombolysis and confirmed occlusion of the left anterior descending artery. Further studies are needed to evaluate the role of high-resolution contrast-enhanced CT with or without coronary angiography in the workup of suspected myocardial infarction in the setting of a normal ECG.

[Immediate hypersensitivity reactions to iodinated contrast agents used in radiology: a review]. / Mise au point sur les réactions d'hypersensibilité immédiate aux produits de contraste iodés (PCI).

The use of iodinated contrast agents (IC) has become common practice nowadays in the daily diagnostic and therapeutic procedures in radiology. Immediate hypersensitivity reactions occurring up to the first hour after injection of IC, can be of serious consequences, occasionally leading to death. This justifies the establishment of a prevention algorithm, including a sharp identification of those at risk and the implementation of premedication with corticosteroids. A history of previous reaction to IC is the major risk factor of a new reaction. Other risk factors include asthma, atopy and cardiomyopathy. The factors that influence the severity of the hypersensitivity allergic reactions are female gender, age, and taking beta blockers or ACE inhibitor drugs.

[Risk factors of pneumothorax and hemorrhage in lung biopsy: a single institution experience]. / Facteurs de risque du pneumothorax et de l'hémorragie associés a la biopsie pulmonaire: une expérience unicentrique.

OBJECTIVES: CT-guided transthoracic lung biopsy is widely used in pulmonary lesions diagnosis. This technique rarely entails severe complications such as pneumothorax and pulmonary hemorrhage which call for adequate candidates screening. The aim of our study is to statistically assess risk factors related to these two main complications, and determine the best diagnostic workup. MATERIALS AND METHODS: This retrospective study includes 110 patients who underwent CT-guided transthoracic biopsy of a pulmonary lesion. Rates of pneumothorax and pulmonary hemorrhage, as well as their severity, were evaluated, and a correlation with factors related to patients, lesions and biopsy technique were statistically analyzed. RESULTS: Higher rates of complications are significantly found with multiple punctures (pneumothorax risk multiplied by 7.4), longer intra-parenchymal needle tract (5 and 7% higher risk of pneumothorax and hemorrhage for every 1 mm increase in depth), and with smaller lesions (2 and 5% lower risk respectively for pneumothorax and hemorrhage for every 1 cm increase in lesion size). The presence of an interposing rib is associated with a higher rate of hemorrhage. CONCLUSION: Transthoracic lung biopsy is a minimally invasive technique. However, the presence of associated risk factors must lead to consider another diagnostic method.

Ultrasound as an adjunct to radiography in minor musculoskeletal pediatric trauma.

PURPOSE: To assess the value of ultrasound as an adjunct to radiography in minor musculoskeletal pediatric trauma. METHODS: Fifty children with 53 suspected fractures were referred for upper and/or lower limbs X-rays, followed by ultrasound. On radiography, we noted presence of fracture, of soft tissue thickening, or absence of any lesion. On ultrasound, we noted presence of fracture, of soft tissue lesion, or absence of lesions. RESULTS: A fracture was seen on both examinations in 25 patients with 28 fractures.In 4 patients where only soft tissue thickening was seen on radiography, ultrasound showed fracture in 1 patient, hematoma in 1 patient and was normal in 2 patients. In another patient with a doubtful diagnosis of fracture on radiography, ultrasound was normal. In 20 patients with normal X-rays, ultrasound showed fracture in 6 patients, hematoma in 7 patients and was normal in 7 patients. CONCLUSION: Ultrasound was helpful as an adjunct to radiography, it yielded additional bone (7/50 patients) and soft tissue (8/50 patients) diagnostic information in 30% of patients. However, ultrasound remains operator-dependent and can be used only in particular circumstances, especially in children with normal X-rays and a high index of clinical suspicion for an occult or subradiological fracture.

Lateral shelf acetabuloplasty in the treatment of Legg-Calvé-Perthes disease: improving mid-term outcome in severely deformed hips.

PURPOSE: To evaluate the efficacy and safety of lateral shelf acetabuloplasty in Legg-Calvé-Perthes (LCP) hips classically associated with poor prognosis. METHODS: A retrospective study was conducted on 30 consecutive pediatric patients (average age 8.6 years) presenting with a severe and progressive form of LCP disease, with (16 hips) or without (14 hips) femoral varus osteotomy (FVO), and treated by lateral shelf acetabuloplasty. Shelf was done on hips presenting an aspherical incongruency with flattening, subluxation, and lack of femoral head coverage, as demonstrated on pre-operative radiographs and arthrography. All patients were reexamined at an average follow-up of 9.5 years (range 5.2-12 years). Clinical, radiological, and computed tomography scan evaluations were undertaken. Stulberg and Mose classifications were applied as radiological indicators of prognosis. Statistical analysis was performed using Student's t test and the Pearson correlation test with variance analysis for repetitive measures. RESULTS: At the last follow-up, all patients were pain free and had normal or almost normal hip motion. Twenty-seven patients are now able to walk normally or with a slight limp. Eighteen hips are classified as Stulberg 1 or 2, and 18 hips are classified as Mose 1 or 2. The average neck-shaft angle is 127°. A statistically significant improvement in the majority of radiographic parameters was found. There was no statistically significant worsening of leg length discrepancy following the procedure. The scanographic study found neither offset nor migration of the shelf in any of the hips. The average coronal and anteroposterior length of the shelf was 9.9 and 25 mm, respectively. A borderline positive correlation was found between Wiberg angle improvement and young age at the time of surgery. There was no statistically significant difference between hips that underwent shelf procedures alone and those in which it was combined with FVO. CONCLUSION: Lateral shelf acetabuloplasty improves the outcome of hips with severe LCP. The combined procedure insures a better and lasting coverage and remodeling of the femoral head, while preserving acetabular roof growth.

[Anatomy of the larynx with 64-channel multidetector CT]. / Anatomie du larynx au scanner 64 canaux.

Knowledge of axial anatomy of the different laryngeal structures, identification of the plan of the cords, and relations between the true and false vocal cords is essential for laryngeal surgery where anatomical and radiological correlation is necessary for optimal orientation and guidance. This review constitutes an atlas of axial anatomy of the larynx obtained from a multidetector CT scan, describing the skeletal cartilage, the different folds constituted by laryngeal ligaments covered by mucosa, and the fatty laryngeal spaces. It shows that CT scan and the different reconstructions specifically virtual endoscopy are a valuable adjunct in laryngeal exploration.

BI-RADS: what do we need to know? Advantages and limitations.

BI-RADS (Breast Imaging and Reporting Data System) is meant to transform breast imaging language to a universal one by defining the related descriptive terms, the statistical definitions, and providing recommendations for radiological reports and data archiving system. The latest version covers three imaging modalities, i.e., mammography, ultrasound and MRI. It cannot replace personal experience, good knowledge of the literature and continuous medical education. Despite its limits, it has proven to be a useful tool for communication between physicians of different specialties and researchers. The knowledge of its basic elements is necessary for all physicians who deal with breast diseases and breast cancer screening.

Cerebellar hematoma complicating 600 mg loading dose of clopidogrel in combination with tirofiban.

A patient admitted for coronary angioplasty received a loading dose of Clopidogrel 600 mg, in combination with an infusion of Tirofiban and one prophylactic dose of Enoxaparin. He developed massive cerebellar hemorrhage and underwent urgent surgery. Recovery was fortunately complete and reintroduction of antiplatelet agents was guided by platelet aggregation inhibition test.

Extracystic biliary carcinoma associated with anomalous pancreaticobiliary junction and cysts.

Anomalous pancreaticobiliary junction with cystic dilatation of the biliary tract is usually associated with carcinoma arising from the cyst wall. We report an extracystic location of biliary carcinoma in the presence of anomalous pancreaticobiliary junction and cysts in a patient with obstruction of the origin of the left hepatic duct who underwent hepatobiliary resection. Cholangiocarcinoma was found to have arisen in a noncystic left hepatic duct, in conjunction with cystic dilatation involving both the cystic and common bile ducts. The present case supports a relationship between anomalous pancreaticobiliary junction and biliary carcinogenesis that may affect the extracystic biliary tree.

Spontaneous detorsion of the ovary: can it be diagnosed by MRI?

PURPOSE: To determine whether recent progress in imaging has made it possible to diagnose spontaneous detorsion, which is an accepted concept in the gynecological literature but until now has been a presumptive diagnosis that could not be confirmed because of the lack of imaging proof. MATERIALS AND METHODS: We searched for patients who had a diagnosis of spontaneous detorsion on MRI between January 2000 and January 2003, and selected only patients who met a selection of strict criteria, including mainly enlargement and hyperintensity of ovarian stroma on T2-weighted (T2W) images, clinical findings compatible with torsion and detorsion, and return of the stroma to normal size on follow-up examinations. Other signs of torsion, such as tubal thickening, were appreciated but not mandatory. Clinical follow-up for at least three years was available. RESULTS: Four patients met the study criteria. No stabilizing procedure was performed in the ovaries. One patient recurred and lost her ovary. CONCLUSION: The diagnosis of torsion followed by spontaneous detorsion was made with high probability in a selected number of patients. The clinical management of such patients remains a matter of debate. Laparoscopy with oophoropexy would be useful for young patients in whom close follow-up cannot be achieved.

Variable MR findings in ovarian functional hemorrhagic cysts.

PURPOSE: To describe the magnetic resonance (MR) findings in ovarian functional hemorrhagic cysts (FHC). MATERIALS AND METHODS: A total of 21 patients with 22 FHC, proven by follow-up ultrasound (US) in 11 women and surgery in 10 women, had US and MR examinations within 24 hours. The study was limited to cysts with obvious an echogenic pattern. All patients had T2-weighted fast spin echo (FSE), T1-weighted spin echo (SE), and T1-weighted SE fat-suppressed sequences. RESULTS: Four cysts (18%) were hypointense on T1-weighted-images without and with fat suppression, and hyperintense on T2-weighted-images. Five cysts (23%) were hypointense on T1-weighted images without and with fat suppression but heterogenous on T2-weighted images. Five cysts (23%) were hypointense on T1-weighted images but showed intermediate signal intensity on T1-weighted fat suppression images and heterogenous signal intensity on T2-weighted images. Two cysts (9%) were entirely intermediate on T1-weighted images. Five cysts (23%) displayed high signal intensity occupying less than 30% of the cystic content on T1-weighted images and one cyst (5%) displayed high signal intensity occupying more than 30% of the cystic content. CONCLUSION: Despite an obvious echogenic pattern on US, 64% of FHC were hypointense on T1-weighted images and 18% were also hyperintense on T2-weighted images. Only 36% demonstrated intermediate or high signal intensity on T1-weighted images.

Multilocular adenomatoid tumor of the ovary: ultrasonographic findings.

We report the sonographic findings of a rare benign ovarian tumor in a 69-year-old woman. Transvaginal ultrasonography showed a cystic multilocular lesion with a vascularized central solid portion of the left ovary. Surgery revealed an adenomatoid tumor. Adenomatoid tumors are benign lesions of mesothelial origin, usually solid in nature and rarely located in the ovaries. (c) 2005 Wiley Periodicals, Inc. J Clin Ultrasound 33:233-236, 2005.

Adnexal torsion: magnetic resonance findings in the viable adnexa with emphasis on stromal ovarian appearance.

PURPOSE: To evaluate ultrasound (US) and magnetic resonance (MR) findings in the viable twisted adnexa. MATERIALS AND METHODS: Ten patients underwent US and MR studies before surgical detorsion. Corrected cross-sectional area of the ovary was defined as cross-sectional area minus areas of cysts and follicles superior to 1 cm. On T2-weighted images, signal intensity of the stroma was graded as type 1 when it was equal to that of urine and type 2 when it was less than that of urine but markedly more than the contralateral side. RESULTS: The tube was twisted in six cases and the ovary in nine cases. All adnexa were viable. The largest ovarian cross-sectional area and the largest corrected ovarian cross-sectional area of the twisted ovary were significantly larger than those of the contralateral ovary (P = 0.043 for US; P = 0.012 and 0.017, respectively, for MR). These ovaries contained types 1 and 2 hyperintensity in six cases and only type 2 hyperintensity in three cases. Tubal thickening was seen on MR in five cases. CONCLUSION: Tubal thickening, enlargement of ovarian stroma as reflected by the corrected cross-sectional area, and hyperintensity of this stroma on T2-weighted images probably related to edema were useful findings in these viable torsions.

Vascular manifestations of Behçet's disease. Eighteen cases among 140 patients.

OBJECTIVES: To describe the features, prognosis, and treatment of vascular involvement in Behçet's disease (BD). PATIENTS: Among 140 patients with BD seen at the Hôtel-Dieu Hospital in Beirut between 1980 and 2000, 18 (13%) had vascular involvement and were included in this retrospective study. All these patients fulfilled International Study Group criteria for BD. RESULTS: Men with BD were more likely to have vascular involvement (13/77, 17%) than women (5/63, 8%) (P = 0.12) and were younger at diagnosis of vascular disease (32 +/- 7 vs. 36 +/- 7.5 years; P < 0.01). Many patients had vascular disease at more than one site: 17 had thrombophlebitis, 10 had arterial thromboses, and one had an aneurysm. Thrombophlebitis was more common in men (82% vs. 18%; P < 0.03) and arterial occlusion in women (70% vs. 30%; P > 0.05). Caval thrombosis and arterial occlusions were the most serious complications. Combined treatment with glucocorticoids, anticoagulants, and immunosuppressants was effective in superior vena cava syndrome and extracranial arterial occlusion. CONCLUSION: Vascular manifestations of BD are common in Lebanon, particularly venous lesions. Aneurysms are seen less often than arterial occlusions. Medical treatment may be sufficient in superior vena cava syndrome and arterial occlusion.