Subject(s)
Hemangioma/pathology , Spinal Cord Neoplasms/pathology , Adolescent , Humans , Male , NeckABSTRACT
The cranial nerves, due to its location, are not infrequently involved in the nasopharyngeal neoplasm evolutionary course. In this paper we describe two cases in which the neoplastic infiltration in both cavernous sinuses brought the appearance of an acute bilateral ophthalmolegia on. This symptomatology meant, in the first case, the onset of disease. In the second one, it was the reason of consultation. Later we discuss the topographic location of the damages in both cavernous sinuses considering the observed neurological shortcomings. Finally we approach a short revision of the causes of bilateral ophthalmoplegia found in literature, as well as an evaluation of different radiological diagnosis methods for this kind of damages.
Subject(s)
Nasopharyngeal Neoplasms/complications , Ophthalmoplegia/etiology , Acute Disease , Female , Humans , Middle AgedABSTRACT
Two cases of necrotic myelopathy are presented. This is a very rare paraneoplasic syndrome. One patient had clear cell renal carcinoma and other had lymphatic metastasis of malignant melanoma without filiation of the primary tumor. The complete spinal study (MNR, CT, myelography) proved normal. Diagnosis is possible when all other causes of spinal disease have been discarded. Nowadays, it is possible to diagnose this disease premortem. The international literature reviewed showed 31 cases published since 1903, associated mainly to malignant diseases such as lymphomas, lung cancer, renal carcinoma, breast cancer, leukemias, etc. The differential diagnosis appears in the comments, as well as the presentation and evolution of the cases described up until now.
Subject(s)
Adenocarcinoma/pathology , Carcinoma, Renal Cell/pathology , Kidney Neoplasms/pathology , Melanoma/pathology , Myelitis/pathology , Neoplasms, Unknown Primary/pathology , Paraneoplastic Syndromes/pathology , Adult , Humans , Lymphatic Metastasis , Male , Middle Aged , Necrosis/pathologyABSTRACT
We present five cases of Syringomyelia, three of which are associated with Arnold-Chiari malformation, establishing a comparison between the diagnostic effectivity of CT scan and Nuclear Magnetic Resonance (NMR). In all five cases the lesion was detected by NMR, but not by CT scan. The advantages of NMR over CT scan were evaluated concluding that NMR is more sensible and should be of first choice in the diagnosis of Syringomyelia, permitting also, a better study of the extension of the cavities as well as its control after surgical treatment.
Subject(s)
Syringomyelia/diagnosis , Adult , Female , Humans , Magnetic Resonance Imaging , Male , Middle Aged , Syringomyelia/diagnostic imaging , Tomography, X-Ray ComputedABSTRACT
2 exceptional cases of neurobrucellosis, which manifested as intracranial hypertension and subdural hemorrhage, are presented. A revision of the subject was carried out. We consider that the association of two antibiotics (rifampin, doxycycline or trimethoprim/sulfamethoxazole) are valid and should be administered until the symptoms disappear and the CSF becomes normal. We suggest that all nervous system symptoms in our area, which are not clear, should be studied for brucella because sometimes these are the only features of neurobrucellosis.
Subject(s)
Brucellosis/diagnosis , Nervous System Diseases/diagnosis , Pseudotumor Cerebri/diagnosis , Subarachnoid Hemorrhage/diagnosis , Adolescent , Brucellosis/complications , Diagnosis, Differential , Female , Humans , Male , Nervous System Diseases/etiology , Pseudotumor Cerebri/etiology , Subarachnoid Hemorrhage/etiologyABSTRACT
A case of deficiency of cobalamin coenzyme synthesis whose first manifestation was encephalopathy with seizures and no trace of megaloblastic anemia is presented. After a while, signs of posterior cord and polyneural disfunction were detected. We highlight the rareness of the case and the difficulty of the diagnosis because of the discrepancy between neurologic and hematologic signs, as well as the need for early diagnosis which is an important factor for observing therapeutic response.
