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1.
Curr Eye Res ; 47(3): 443-449, 2022 03.
Article in English | MEDLINE | ID: mdl-34906017

ABSTRACT

PURPOSE/AIM: To evaluate the visual outcomes, refractive outcomes and rotational stability of a toric piggyback intraocular lens (1stQ AddOn, GmbH, Mannheim, Germany) for astigmatic refractive error in pseudophakic eyes. MATERIALS AND METHODS: Visual and refractive outcomes were assessed based on the standard graphs for reporting refractive surgery outcomes. Rotational stability was assessed according to the Intraocular Lens (IOL) standards of the International Organisation for Standards. RESULTS: Twenty-two eyes of 17 patients (age: 65.1 ± 9.3 years) underwent toric piggyback IOL insertion. After a minimum follow-up of 3 months, 18 eyes (82%) achieved an uncorrected distance visual acuity (UDVA) of 0.00 logMAR (20/20) or better and all eyes achieved 0.1 logMAR (20/25). Mean UDVA improved from 0.27 ± 0.03 to 0.12 ± 0.03 and 0.04 ± 0.04 at one and 3 months (all p < .05). Nineteen eyes (86%) achieved an UDVA at least equal to the pre-operative corrected distance visual acuity (CDVA). No eyes lost more than one line of CDVA. All eyes achieved within 0.5D of target spherical equivalent (SE). In 18 eyes (82%), the residual astigmatism magnitude was 0.5D or less. The mean absolute difference between the target axis and the achieved axis 1 and 3 months postoperatively was 2.5° ± 2.7° and 3.2° ± 3.3°, respectively. The final IOL orientation was within 10 degrees of target axis in 19 of 22 (86.4%) eyes, within 20 degrees in 21 of 22 (95.2%) eyes and within 30 degrees in 22 of 22 (100%) eyes. IOL rotational repositioning was required in two eyes (9.1%). CONCLUSIONS: In this cohort of patients, the 1stQ AddOn toric monofocal piggyback IOL resulted in very good visual and refractive outcomes and showed reasonable rotational stability. This IOL appears to be an effective treatment option for residual astigmatic refractive error in pseudophakic eyes.


Subject(s)
Astigmatism , Lenses, Intraocular , Phacoemulsification , Aged , Astigmatism/surgery , Humans , Lens Implantation, Intraocular/methods , Middle Aged , Prospective Studies , Refraction, Ocular
2.
Clin Exp Ophthalmol ; 38(3): 309-13, 2010 Apr.
Article in English | MEDLINE | ID: mdl-20447128

ABSTRACT

Herpes simplex virus (HSV) keratitis is a common cause of ocular morbidity. Resistance to aciclovir is probably under recognized. We describe three cases of aciclovir-resistant herpes simplex virus keratitis treated with systemic foscarnet and present a review of the pharmacological options available to manage this condition.


Subject(s)
Acyclovir/therapeutic use , Antiviral Agents/therapeutic use , Drug Resistance, Viral , Keratitis, Herpetic/drug therapy , Acyclovir/administration & dosage , Administration, Oral , Administration, Topical , Aged, 80 and over , Antiviral Agents/administration & dosage , Blindness/virology , Humans , Keratitis, Herpetic/complications , Male , Middle Aged , Treatment Outcome
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