ABSTRACT
The advantages of transporting mammalian preimplantation embryos rather than postnatal living animals include reduced costs of transportation and rapid dissemination of genetic material between countries. However, the risk of transmission of diseases through the embryos must be considered. The disease control potential of embryos will depend on proper handling and washing, and the integrity of zona pellucida. Researches on embryo-pathogen interactions have shown that some pathogens are carried through the gametes and others could not infect the gametes. Some pathogens were found to adhere to the zona pellucida and others could penetrate the zona pellucida. To date, data presented appear to suggest no concrete model guidelines for embryo-pathogen interaction. The interaction seems to depend on the species and the pathogen involved.