[Assessment of antiischemic efficacy of balloon angioplasty, coronary bypass surgery and conservative therapy after myocardial infarction in patients with single coronary artery disease. Three year prospective study]. / Otsenka antiishemicheskoi éffektivnosti ballonnoi angioplastiki, koronarnogo shuntirovaniia i konservativnoi terapii u postinfarktnykh bol'nykh s odnososudistym stenozirovaniem koronarnogo rusla pri 3-letnem prospektivnom nabliudenii.

Efficacy of balloon angioplasty, coronary bypass surgery and conservative therapy in postmyocardial infarction patients with single coronary artery disease was assessed in 3 year prospective study. Positive clinical effect persisted after coronary artery bypass grafting (CABG) in 78 and 73% of patients and after balloon angioplasty in 60 and 40% of patients in 1 and 3 years, respectively. Significant decreases of number of anginal attacks (by 94.1 and 74.1%, respectively), nitroglycerin consumption (by 93.6 and 74.8%, respectively) and dimensions of ischemic perfusion defects (by 68.8 and 33.7%, respectively) were observed 1 year after both CABG and angioplasty. Lowering of exercise tolerance (by 11.1%), increase of nitroglycerin consumption (by 15.8%) and worsening of myocardial perfusion (by 9%) were observed after 3 years in conservatively treated patients.

[Early and late (during 3 years) results of coronary bypass operation in patients with ischemic heart disease with moderate dyslipoproteinemia]. / Rannye i otdalennye (cherez 3 goda) rezul'taty koronarnogo shuntirovaniia u bol'nykh ishemicheskoi bolezn'iu serdtsa s umerennoi dislipoproteidemiei.

AIM: The study of efficacy of rehabilitation and clinical-instrumental characteristics of coronary failure in patients with ischemic heart disease (IHD) of high functional classes and moderate dyslipoproteinemia early (1.6 months) and late (1 and 3 years) after coronary by-pass operation. MATERIALS AND METHODS: The examination covered 119 males with IHD (mean age 51.8 +/- 6.9 years) 1.6 months and 3 years after coronary by-pass operation. Lipid spectrum of blood plasma, frequency of anginal attacks, 24-h nitroglycerin requirement, results of bicycle exercise and loading myocardial scintigraphy were assessed. The patients were divided into two groups. In 82 patients of group 1 total cholesterol ranged within 3 years after the surgery from 5.2 to 6.5 mmol/l, 37 patients of group 2 had no lipid disorders. RESULTS: Within 12 months after direct myocardial revascularization, the groups had similar clinical-instrumental characteristics. 3 years after the operation, patients of group 1 exhibited a rise in anginal attacks frequency, nitroglycerin requirement, size of unstable perfusion defects by 84.6, 88.8 and 26.4%, respectively. Exercise tolerance diminished by 18.7%. CONCLUSION: Moderate defects in lipid metabolism influence progression of coronary failure. This becomes especially pronounced within 3 years after coronary by-pass operation.

[The clinico-functional characteristics of the reversal of coronary and myocardial failure in IHD patients after direct myocardial revascularization]. / Kliniko-funktsional'nye osobennosti obratnogo razvitiia koronarnoi i miokardial'noi nedostatochnosti u bol'nykh IBS posle priamoi revaskuliarizatsii miokarda.

184 ischemic heart disease (IHD) patients, all males, were investigated before, one month and one year after coronary artery bypass grafting. Significant changes in central hemodynamics and in exercise tolerance were noted in the course of rehabilitation. These were more significant in patients with multiple atherosclerosis lesions of the coronary bed whereas clinical effect was more favourable in patients with favourable course of IHD. The above trends in hemodynamics, exercise tolerance and clinical symptoms following surgical revascularization were observed during the first 6 months.