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3.
Sci Total Environ ; 853: 158432, 2022 Dec 20.
Article in English | MEDLINE | ID: mdl-36057308

ABSTRACT

The Amazon Continental Shelf (ACS) has a coastline of ∼1000 km and is situated in a humid equatorial region with two distinct seasons, wet and dry, and two transitional climatic periods. A total of eight oceanographic cruises were conducted to investigate the dynamics of the inorganic nutrients dissolved in the surface layer of the water column of the ACS and their associations with Sargassum blooms. An excess of nitrogen-N* (NH4+ = 0.01-9.30 µmol l-1) was verified through the salinity gradient from the continent to the ACS, mainly during the period of maximum discharge of the Amazon and Tocantins-Pará rivers. The highest NH4+ concentrations coincided with the occurrence of macrophyte (Sargassum sp.) blooms in the mesohaline and oceanic regions. During this period the high values of NH4+ accompany the low values of Sea Surface Salinity (SSS), indicating the advection of the Amazonian plume towards the Caribbean Sea. In the Sargassum belts we observed a N:P ratio = 60:1 during wet period, while outside this region, the N:P ratio was 34:1. According to DIN vs. AOU ratio, we observed that heterotrophic processes prevail over productive processes, mainly in the mesohaline and low salinity regions. Nitrogen concentrations from runoff, mainly from hydrographic basins, showed significant increases in the last decade, mainly due to anthropogenic factors such as agriculture, deforestation, livestock, urban sewage (domestic and industrial), and demographic growth of the population in the Tocantins-Pará Basin. Additionally, associations of diatoms and cyanobacteria provide more nitrogen in the mesohaline and oceanic regions that nourishes Sargassum blooms. Seasonal comparisons (October and April) of Sargassum belts with other studies, indicated that currents play a fundamental role in the transport of these macrophytes from the east edge (Africa) to the west edge (Brazil and French Guiana) towards the Caribbean Sea in the tropical Atlantic.


Subject(s)
Sargassum , Sewage , Rivers , Nitrogen , Water
4.
Am J Physiol Cell Physiol ; 322(5): C896-C912, 2022 05 01.
Article in English | MEDLINE | ID: mdl-35319900

ABSTRACT

Receptor-ligand interactions play an important role in many biological processes by triggering specific cellular responses. These interactions are frequently regulated by coreceptors that facilitate, alter, or inhibit signaling. Coreceptors work in parallel with other specific and accessory molecules to coordinate receptor-ligand interactions. Cell surface heparan sulfate proteoglycans (HSPGs) function as unique coreceptors because they can bind to many ligands and receptors through their HS and core protein motifs. Cell surface HSPGs are typically expressed in abundance of the signaling receptors and, thus, are capable of mediating the initial binding of ligands to the cell surface. HSPG coreceptors do not possess kinase domains or intrinsic enzyme activities and, for the most part, binding to cell surface HSPGs does not directly stimulate intracellular signaling. Because of these features, cell surface HSPGs primarily function as coreceptors for many receptor-ligand interactions. Given that cell surface HSPGs are widely conserved, they likely serve fundamental functions to preserve basic physiological processes. Indeed, cell surface HSPGs can support specific cellular interactions with growth factors, morphogens, chemokines, extracellular matrix (ECM) components, and microbial pathogens and their secreted virulence factors. Through these interactions, HSPG coreceptors regulate cell adhesion, proliferation, migration, and differentiation, and impact the onset, progression, and outcome of pathophysiological processes, such as development, tissue repair, inflammation, infection, and tumorigenesis. This review seeks to provide an overview of the various mechanisms of how cell surface HSPGs function as coreceptors.


Subject(s)
Heparan Sulfate Proteoglycans , Signal Transduction , Cell Membrane/metabolism , Heparan Sulfate Proteoglycans/chemistry , Heparan Sulfate Proteoglycans/metabolism , Heparitin Sulfate/metabolism , Intercellular Signaling Peptides and Proteins , Ligands , Signal Transduction/physiology
5.
Methods Mol Biol ; 2303: 605-625, 2022.
Article in English | MEDLINE | ID: mdl-34626410

ABSTRACT

Heparan sulfate proteoglycans (HSPGs) are at the forefront of host-microbe interactions. Cell surface HSPGs are thought to promote infection as attachment and internalization receptors for many bacterial pathogens and as soluble inhibitors of host immunity when released from the cell surface by ectodomain shedding. However, the importance of HSPG-pathogen interactions in vivo has yet to be clearly established. Here we describe several representative methods to study the role of HSPGs in systemic bacterial infections, such as bacteremia and sepsis. The overall experimental strategy is to use mouse models to establish the physiological significance of HSPGs, to determine the identity of HSPGs that specifically promote infection, and to define key structural features of HSPGs that enhance bacterial virulence in systemic infections.


Subject(s)
Bacterial Infections , Animals , Cell Membrane , Disease Models, Animal , Heparan Sulfate Proteoglycans , Heparitin Sulfate , Mice , Sepsis
6.
Rev. colomb. cienc. pecu ; 33(4): 228-238, Oct.-Dec. 2020. tab
Article in English | LILACS-Express | LILACS | ID: biblio-1376894

ABSTRACT

Abstract Background: The addition of synthetic methionine to growing pig diets should consider the requirements of the methionine+cysteine complex, as most cysteine is obtained through dietary methionine. Objective: To determine an optimal level of methionine+cysteine (Met+Cys) in growing pig diets. Methods: Ninety-nine hybrid (Yorkshire×Landrace×Duroc) barrows were used in a completely randomized design (initial body weight: 25.90±3.99 kg). Nine levels of Met+Cys (0.500, 0.525, 0.550, 0.575, 0.600, 0.625, 0.650, 0.675, and 0.700%) were evaluated during 35 days. To determine a multi-objective optimal level of Met+Cys, growth performance and strongly related carcass traits were evaluated. Results: Average daily feed intake (ADFI) and feed:gain ratio (FGR) showed a linear response to the dietary Met+Cys level (p<0.05), with estimated optimal concentration at 0.700%. Average daily gain (ADG) did not show any effect on the Met+Cys level (p>0.05). Carcass characteristics were not affected by the Met+Cys concentration (p>0.05). The multi-objective optimal level for ADG, ADFI, and FGR was 0.667% Met+Cys. Conclusions: According to our results, 0.667% Met+Cys is the best concentration in diets for growing pigs.


Resumen Antecedentes: Las dietas para cerdos en crecimiento deben adicionarse con metionina sintética para suplir los requerimientos del complejo metionina+cisteína (Met+Cis), pues ellos producen gran parte de la cisteína que requieren a partir de la metionina dietaría. Objetivo: determinar el nivel óptimo multiobjetivo de Met+Cis en dietas para cerdos en crecimiento. Métodos: noventa y nueve machos castrados híbridos (Yorkshire×Landrace×Duroc) se utilizaron en un diseño completamente al azar (peso vivo inicial: 25,90±3,99 kg). Se evaluaron nueve niveles de Met+Cys (0,500, 0,525, 0,550, 0,575, 0,600, 0,625, 0,650, 0,675 y 0,700%) durante 35 d. Para determinar el nivel óptimo multiobjetivo de Met+Cis se consideraron las variables de rendimiento de crecimiento y características de la canal que mantienen una fuerte interrelación. Resultados: el promedio de consumo de alimento diario (ADFI) y la conversión alimenticia (FGR) mostraron una respuesta lineal al nivel de Met+Cis en la dieta (p<0,05), con una concentración óptima estimada en 0,700%. El nivel de Met+Cis no afecto a la ganancia diaria de peso (ADG; p>0,05). La concentración de Met+Cis tampoco afectó las características de la canal (p>0,05). El nivel óptimo multi- objetivo de Met+Cis para ADFI, FGR y ADG fue 0,667%. Conclusión: los resultados indican que 0,667% de Met+Cis es la mejor concentración en la dieta para cerdos en crecimiento.


Resumo Antecedentes: a adição de metionina em dietas para suínos em crescimento deve ser feita para atender às exigências do complexo metionina+cisteína (Met+Cis), porque grande parte da cisteína é obtida através da dieta com metionina. Objetivo: determinar o nível multiobjetivo ótimo de Met+Cis em dietas para suínos em crescimento. Métodos: noventa e nove suínos machos castrados híbridos (Yorkshire×Landrace×Duroc) foram utilizados em delineamento inteiramente casualizado, com peso inicial de 25,90±3,99 kg. Nove níveis de Met+Cis (0,500, 0,525, 0,550, 0,575, 0,600, 0,625, 0,650, 0,675 y 0,700%) foram avaliados em suínos em crescimento por 35 d. Para determinar o nível multiobjetivo ótimo de Met+Cis, foram consideradas as variáveis de comportamento de crescimento e características do canal que mantêm uma forte inter-relação. Resultados: a ingestão média diária de alimentos (ADFI) e a conversão alimentar (FGR) mostraram uma resposta linear ao nível de Met+Cis na dieta (p<0,05), estimando a concentração ótima em 0,700%. O ganho de peso diário (ADG) não mostrou efeito devido ao nível de Met+Cis na dieta (p>0,05). As características da carcaça não foram afetadas pela concentração de Met+Cis na dieta (p>0,05). Com ADFI, FGR e ADG, o nível ótimo de Met+Cis foi obtido, encontrando este nível em 0,667%. Conclusões: os resultados indicam que 0,667% de Met+Cis é a melhor concentração na dieta para suínos em crescimento.

7.
PLoS Pathog ; 16(5): e1008497, 2020 05.
Article in English | MEDLINE | ID: mdl-32453780

ABSTRACT

Heparan sulfate proteoglycans (HSPGs) are at the forefront of host-microbe interactions. Molecular and cell-based studies suggest that HSPG-pathogen interactions promote pathogenesis by facilitating microbial attachment and invasion of host cells. However, the specific identity of HSPGs, precise mechanisms by which HSPGs promote pathogenesis, and the in vivo relevance of HSPG-pathogen interactions remain to be determined. HSPGs also modulate host responses to tissue injury and inflammation, but functions of HSPGs other than facilitating microbial attachment and internalization are understudied in infectious disease. Here we examined the role of syndecan-1 (Sdc1), a major cell surface HSPG of epithelial cells, in mouse models of Listeria monocytogenes (Lm) infection. We show that Sdc1-/- mice are significantly less susceptible to both intragastric and intravenous Lm infection compared to wild type (Wt) mice. This phenotype is not seen in Sdc3-/- or Sdc4-/- mice, indicating that ablation of Sdc1 causes a specific gain of function that enables mice to resist listeriosis. However, Sdc1 does not support Lm attachment or invasion of host cells, indicating that Sdc1 does not promote pathogenesis as a cell surface Lm receptor. Instead, Sdc1 inhibits the clearance of Lm before the bacterium gains access to its intracellular niche. Large intravascular aggregates of neutrophils and neutrophil extracellular traps (NETs) embedded with antimicrobial compounds are formed in Sdc1-/- livers, which trap and kill Lm. Lm infection induces Sdc1 shedding from the surface of hepatocytes in Wt livers, which is directly associated with the decrease in size of intravascular aggregated NETs. Furthermore, administration of purified Sdc1 ectodomains or DNase inhibits the formation of intravascular aggregated neutrophils and NETs and significantly increases the liver bacterial burden in Sdc1-/- mice. These data indicate that Lm induces Sdc1 shedding to subvert the activity of Sdc1 ectodomains to inhibit its clearance by intravascular aggregated NETs.


Subject(s)
Extracellular Traps/immunology , Listeria monocytogenes/immunology , Listeriosis/immunology , Neutrophils/immunology , Syndecan-1/immunology , Animals , Extracellular Traps/genetics , Hepatocytes/immunology , Hepatocytes/pathology , Listeria monocytogenes/pathogenicity , Listeriosis/genetics , Listeriosis/pathology , Mice , Mice, Inbred BALB C , Mice, Knockout , Neutrophils/pathology , Protein Domains , Syndecan-1/genetics
8.
Trop Anim Health Prod ; 51(5): 1057-1063, 2019 Jun.
Article in English | MEDLINE | ID: mdl-30604329

ABSTRACT

The objective of this study was to evaluate the biochemical, behavioral, and physiological parameters in pregnant sows of native and improved crossbreeds reared within a thermally stressful outdoors system. Twenty pregnant sows of two different genetic groups (native and improved lineage) were used in this research, all animals were distributed in a completely randomized design. The behavioral evaluation was organized in subdivided plots, the sub-plots were the four periods of the day (early morning, morning, afternoon, and night), and the evaluation of physiological parameters were in three periods of the day (9:00 A.M., 12:00 A.M. and 3:00 P.M.), which was conducted for three consecutive days. Blood collection was performed by retro-orbital sinus puncture 1 day before the start of behavior analysis. Glucose levels, total protein, and creatinine showed differences between improved crossbreeds and native animals. It was observed that creatinine and total protein presented larger values for the group of improved crossbreeds, while glucose levels were higher for native animals. While behavioral variables showed behavior indicative of heat stress, as more time was spent by pregnant sows of improved genotypes getting wet, searching for water and staying in outdoors, while native animals showed much more movement behavior during morning and afternoon periods. It was observed differences were observed of time for respiratory rates, while no differences were found for rectal temperature. This indicates that in a region with hot climate, it would be more possible to raise native pregnant sows, due to their rusticity and ability to acclimate to a local condition, according to behavioral evaluation and physiological parameters. Pregnant sows of improved breeding genotypes presented higher difficulties of adaptation than native sows.


Subject(s)
Genotype , Heat-Shock Response , Sus scrofa/physiology , Animal Husbandry/methods , Animals , Brazil , Breeding , Female , Housing, Animal , Pregnancy , Sus scrofa/genetics
11.
REME rev. min. enferm ; 23: e-1260, jan.2019.
Article in English, Portuguese | LILACS, BDENF - Nursing | ID: biblio-1048090

ABSTRACT

OBJETIVO: este estudo objetivou obter e analisar o índice de capacidade para o trabalho (ICT) e a relação com os aspectos individuais e contextuais ao trabalho. MÉTODO: estudo transversal com abordagem quantitativa e caráter descritivo, com 164 profissionais da equipe de Enfermagem de um hospital de grande porte do Triângulo Mineiro, MG, no ano de 2018. Aplicou-se o questionário do ICT acrescido de variáveis sociodemográficas e epidemiológicas. E no tratamento estatístico adotou-se o software Statistical Package for the Social Sciences (SPSS). Para a análise do escore do ICT utilizou-se a análise de variância de medidas repetitivas (ANOVA), e no pós-teste aplicou-se de Tukey e teste de regressão linear. RESULTADOS: houve prevalência do sexo feminino (135, 81%), faixa etária entre 31 e 40 anos (46%) e função atual como técnicos de Enfermagem (74, 45%). No escore geral do ICT, 89 (54%) apresentaram-se com boa capacidade para o trabalho (CT), obtendo entre 37 e 43 pontos. Houve significância entre 41 e 60 anos (p=0,002) e na variável "capacidade de apreciar a vida em relação aos recursos mentais" (p=0,0045). CONCLUSÃO: a idade e os recursos mentais apresentaram-se como as principais variáveis que incidiram diretamente sobre a CT dos trabalhadores de Enfermagem. Assim, as conclusões apresentadas por meio do escore do ICT indicam que quantificar a CT permite a construção de medidas que contribuam para manter e restaurar a saúde do trabalhador, frente ao seu âmbito de trabalho.(AU)


Objective: this study aimed to obtain and analyze the work ability index (WAI) and the relationship with the individual and contextual aspects to work. Method: cross-sectional study with quantitative approach and descriptive character, with 164 nursing staff professionals of a large hospital in Triângulo Mineiro, MG, in the year 2018. The WAI questionnaire plus sociodemographic and epidemiological variables was applied. The statistical treatment adopted the Statistical Package for Social Sciences (SPSS) software. For the analysis of the WAI score, the analysis of variance (ANOVA) of repetitive measures was used, followed by the Tukey test and linear regression were applied. Results: there was a prevalence of females (135.81%), age between 31 and 40 years (46%) and current role as nursing technicians (74.45%). In the overall WAI score, 89 (54%) presented good work ability (WA), obtaining between 37 and 43 points. There was significance between 41 and 60 years (p = 0.002) and in the variable "ability to enjoy life in relation to mental resources" (p = 0.0045). Conclusion: age and mental resources were the main variables that directly affected the WC of nursing personnel. Thus, the conclusions presented through the WAI score indicate that quantifying the WA allows the elaboration of measures that contribute to maintain and restore personnel's' health, in front of their work scope.(AU)


Objetivo: obtener y analizar el índice de capacidad de trabajo (ICT) y la relación con los aspectos individuales y contextuales para trabajar. Método: estudio transversal de enfoque cuantitativo y carácter descriptivo, con 164 profesionales del personal de enfermería de un gran hospital del Triângulo Mineiro, MG, en 2018. Se aplicó el cuestionario del ICT con variables sociodemográficas y epidemiológicas. Para el tratamiento estadístico se adoptó el software Statistical Package for the Social Sciences (SPSS). Para el análisis de la puntuación del ICT utilizamos el análisis de varianza de medidas repetitivas (ANOVA), en la prueba posterior y en la prueba de Tukey y en la prueba de regresión lineal. Resultados: prevalencia de mujeres (135, 81%), edad entre 31 y 40 años (46%) y función actual como técnicos de enfermería (74, 45%). En el puntaje general del ICT, 89 (54%) presentaron buena capacidad de trabajo (CT), con entre 37 y 43 puntos. Hubo significación entre 41 y 60 años (p = 0,002) y en la variable "capacidad de disfrutar la vida en relación con los recursos mentales" (p = 0,0045). Conclusión: la edad y los recursos mentales fueron las principales variables que afectaron directamente la CT del personal de enfermería. Por lo tanto, las conclusiones presentadas a través del puntaje del ICT indican que la cuantificación de la CT permite la construcción de medidas que contribuyen a mantener y restaurar la salud de los trabajadores ante el ambiente laboral.(AU)


Subject(s)
Work Capacity Evaluation , Nursing Research , Occupational Health , Nursing, Team , Job Satisfaction
12.
Rev. enferm. UFPE on line ; 13: [1-3], 2019.
Article in Portuguese | BDENF - Nursing | ID: biblio-1095125

ABSTRACT

Objetivo: investigar a ocorrência de infecções fúngicas e bacterianas nos pacientes portadores de HIV hospitalizados em um hospital universitário. Método: trata-se de estudo quantitativo, descritivo, retrospectivo, tipo transversal. Coletar-se-ão dados dos pacientes que estiveram internados em um hospital universitário, acometidos por infecção pelo HIV, por meio de pesquisa em prontuários impressos e eletrônicos. Resultados esperados: pretende-se conhecer a frequência de infecções fúngicas e bacterianas, especialmente a tuberculose, que acometem o paciente portador do HIV e a eficiência da hemocultura como diagnóstico de infecções bacterianas e fúngicas invasivas.(AU)


Objective: to investigate the occurrence of fungal and bacterial infections in hospitalized HIV patients in a university hospital. Method: this is a quantitative, descriptive, retrospective, cross-sectional study. Data will be collected from patients who were hospitalized in a university hospital, suffering from HIV infection, through research in printed and electronic medical records. Expected results: we intend to know the frequency of fungal and bacterial infections, especially tuberculosis, that affects the patient with HIV and the efficiency of blood culture as a diagnosis of invasive bacterial and fungal infections.(AU)


Objetivo: investigar La ocurrencia de infecciones fúngicas y bacterianas en los pacientes portadores de VIH hospitalizados en un hospital universitario. Método: se trata de un estudio cuantitativo, descriptivo, retrospectivo, tipo transversal. Se recolectarán los datos de los pacientes que estuvieron internados en un hospital universitario, acometidos por infección por el VIH, por medio de investigaciones en prontuarios impresos y electrónicos. Resultados esperados: se pretende conocer la frecuencia de infecciones fúngicas y bacterianas, especialmente la tuberculosis, que afectan al paciente portador del VIH y la eficiencia de la hemocultura como diagnóstico de infecciones bacterianas y fúngicas invasivas.(AU)


Subject(s)
Humans , Male , Female , Bacterial Infections , Tuberculosis, Pulmonary , Acquired Immunodeficiency Syndrome , HIV , AIDS-Related Opportunistic Infections , Hospitalization , Mycoses , Epidemiology, Descriptive , Cross-Sectional Studies , Retrospective Studies
13.
Rev. enferm. UFPE on line ; 13: [1-4], 2019.
Article in Portuguese | BDENF - Nursing | ID: biblio-1095128

ABSTRACT

Objetivo: analisar o perfil epidemiológico, clínico e terapêutico de pacientes com Doença de Fabry, com ênfase na atenção à família. Método: trata-se de um estudo quantitativo, epidemiológico, tipo transversal. Elencar-se-ão, como cenários, uma cidade mineira de grande porte e um hospital universitário. Fundamentar-se-á o estudo em fases e, no primeiro momento, serão analisados os pacientes que fazem acompanhamento ambulatorial. Realizar-se-á, em um segundo momento, utilizando um banco de dados e a aplicação de questionários, um estudo comparativo com dois grupos, um com manifestações de sintomas e em tratamento da doença e outro grupo assintomático e sem tratamento. Levantar-se-ão, nas partes clínica e terapêutica, questões dos antecedentes familiares, alimentação e hidratação, sono/repouso, eliminações (urinária e intestinal), histórico médico da consulta, presença de sinais e sintomas, data do diagnóstico, alergias, regime de tratamento, queixas, dentre outras variáveis presentes. Resultados esperados: devese contribuir, pelos resultados da pesquisa, para a identificação de fragilidades, dificuldades e possíveis soluções, possibilitando a divulgação dos dados e achados em conformidade científica, além de permitir revelar a prevalência dos casos, tornando-os visíveis, estatisticamente.(AU)


Objective: to analyze the epidemiological, clinical and therapeutic profile of patients with Fabry disease, with emphasis on family care. Method: this is a quantitative, epidemiological, cross-sectional study. A large mining town and a university hospital will be listed as scenarios. The study will be based in phases and, at the first moment, will be analyzed the patients who follow the outpatient clinic. In a second moment, using a database and the application of questionnaires, a comparative study with two groups, one with manifestations of symptoms and in treatment of the disease and another group asymptomatic and without treatment will be carried out. Questions about family history, feeding and hydration, sleep / rest, eliminations (urinary and intestinal), medical history of the consultation, presence of signs and symptoms, date of diagnosis, allergies, regimen of treatment, complaints, among other variables present. Expected results: the results of the research should contribute to the identification of fragilities, difficulties and possible solutions, allowing the dissemination of data and findings in scientific compliance, besides revealing the prevalence of the cases, making them statistically visible.(AU)


Objetivo: analizar el perfil epidemiológico, clínico y terapéutico de pacientes con enfermedad de Fabry, con énfasis en la atención a la familia. Método: se trata de un estudio cuantitativo, epidemiológico, tipo transversal. Se enumerarán, como escenarios, una ciudad minera de gran porte y un hospital universitario. Se fundamentará el estudio en fases y, en el primer momento, serán analizados los pacientes que realizan seguimiento ambulatorio. Se realizará en un segundo momento utilizando un banco de datos y la aplicación de cuestionarios, un estudio comparativo con dos grupos, uno con manifestaciones de síntomas y en tratamiento de la enfermedad y otro grupo asintomático y sin tratamiento. En las partes clínicas y terapéuticas, se plantean, en las partes clínica y terapéutica, cuestiones de antecedentes familiares, alimentación e hidratación, sueño/reposo, eliminaciones (urinaria e intestinal), historial médico de la consulta, presencia de signos y síntomas, fecha del diagnóstico, alergias, régimen de tratamiento, quejas, entre otras variables presentes. Resultados esperados: se deben contribuir, por los resultados de la investigación, para la identificación de fragilidades, dificultades y posibles soluciones, posibilitando la divulgación de los datos y hallazgos en conformidad científica, además de permitir revelar la prevalencia de los casos, haciéndolos visibles, estadísticamente.(AU)


Subject(s)
Humans , Male , Female , Health Profile , Family , Clinical Evolution , Fabry Disease , Fabry Disease/epidemiology , Rare Diseases , Epidemiologic Studies , Cross-Sectional Studies
14.
Rev. enferm. UFPE on line ; 13: [1-3], 2019.
Article in Portuguese | BDENF - Nursing | ID: biblio-1095127

ABSTRACT

Objetivos: avaliar a qualidade de vida de acadêmicos regularmente ativos em uma universidade; verificar se existe associação entre qualidade de vida e sintomas depressivos. Método: trata-se de estudo quantitativo, tipo transversal, aplicar-se-ão três questionários estruturados, autoaplicáveis para mensurar o nível da qualidade de vida e índice de depressão entre acadêmicos. Far-se-á a análise estatística descritiva, empregar-se-á o teste Liliefors e usar-se-ão o teste t de Student. Apresentar-se-ão os resultados em forma de figuras. Resultados esperados: realizar-se-á a correlação entre a qualidade de vida dos estudantes dos cursos de graduação da universidade e a incidência de fatores depressivos com o início da vida acadêmica.(AU)


Objectives: to evaluate the quality of life of academically active students in a university; to verify if there is an association between quality of life and depressive symptoms. Method: this is a quantitative cross-sectional study. Three structured, self-administered questionnaires will be applied to measure the level of quality of life and depression index among academics. The descriptive statistical analysis will be done, the Liliefors test will be used and the Student's t-test will be used. The results will be presented in the form of figures. Expected results: the correlation between the quality of life of undergraduate students of the university and the incidence of depressive factors with the beginning of academic life will be realized.(AU)


Objetivos: evaluar la calidad de vida de los académicos regularmente activos en una universidad; comprobar si existe asociación entre calidad de vida y síntomas depresivos. Método: se trata de estudio cuantitativo, tipo transversal, se aplicarán tres cuestionarios estructurados, autoaplicables para medir el nivel de la calidad de vida e índice de depresión entre académicos. Se hará el análisis estadístico descriptivo, se empleará la prueba Liliefors y se utilizarán la prueba t de Student. Se presentarán los resultados en forma de figuras. Resultados esperados: se realizará la correlación entre la calidad de vida de los estudiantes de los cursos de grado de la universidad y la incidencia de factores depresivos con el inicio de la vida académica.(AU)


Subject(s)
Humans , Male , Female , Quality of Life , Students , Student Health , Universities , Depression , Cross-Sectional Studies
15.
Rev. enferm. UFPE on line ; 13: [1-3], 2019.
Article in Portuguese | BDENF - Nursing | ID: biblio-1095129

ABSTRACT

Objetivo: analisar a percepção do doente renal crônico em relação ao trabalho, caracterizando seus impactos físico, mental e social. Método: trata-se de uma pesquisa qualitativa, descritiva. Aplicar-se-ão questionários estruturados, em uma amostra probabilística intencional, para a avaliação dos objetivos da pesquisa (Questionário sociodemográfico e KDQOL-SF™ 1.3). Realizar-se-ão, para a análise dos dados por meio da Análise de Conteúdo. Aplicar-se-ão, para caracterização da amostra (análise de variância), a ANOVA, para a comparação entre grupos de características diferentes, e, por fim, a análise de regressão múltipla, para avaliar que fatores têm maior efeito na percepção dos sujeitos acerca de sua qualidade de vida. Resultados esperados: espera-se evidenciar a intensidade e a frequência das relações entre a doença renal crônica em tratamento hemodialítico e a vida laboral, bem como seu impacto sobre a sua qualidade de vida.(AU)


Objective: to analyze the perception of the chronic renal patient in relation to work, characterizing its physical, mental and social impacts. Method: this is a qualitative, descriptive research. Structured questionnaires will be applied in an intentional probabilistic sample for the evaluation of the research objectives (Sociodemographic Questionnaire and KDQOL-SF ™ 1.3). They will be done, for the analysis of the data through Content Analysis. For the characterization of the sample (analysis of variance), the ANOVA will be used for the comparison between groups of different characteristics, and, finally, the multiple regression analysis, to evaluate which factors have a greater effect on the subjects' perception about their quality of life. Expected results: it is expected to show the intensity and frequency of the relationship between chronic renal disease in hemodialysis and working life, as well as its impact on the quality of life.(AU)


Objetivo: analizar la percepción del paciente renal crónico en relación al trabajo, caracterizando sus impactos físico, mental y social. Método: se trata de una investigación cualitativa, descriptiva. Se aplicarán cuestionarios estructurados, en una muestra probabilística intencional, para la evaluación de los objetivos de la investigación (Cuestionario sociodemográfico y KDQOL-SF ™ 1.3). Se realizarán, para el análisis de los datos por medio del Análisis de Contenido. Se aplicarán, para caracterización de la muestra (análisis de varianza), la ANOVA, para la comparación entre grupos de características diferentes, y, por fin, el análisis de regresión múltiple, para evaluar qué factores tienen mayor efecto en la percepción de los sujetos sobre su calidad de vida. Resultados esperados: se espera evidenciar la intensidad y la frecuencia de las relaciones entre la enfermedad renal crónica en tratamiento hemodialítico y la vida laboral, así como su impacto en su calidad de vida.(AU)


Subject(s)
Humans , Male , Female , Perception , Quality of Life , Work , Occupational Health , Renal Dialysis , Cost of Illness , Renal Insufficiency, Chronic , Epidemiology, Descriptive , Qualitative Research
16.
Rev. enferm. UFPE on line ; 13: [1-11], 2019. ilus, tab, graf
Article in Portuguese | BDENF - Nursing | ID: biblio-1051973

ABSTRACT

Objetivo: analisar os artigos que utilizaram o Índice de Capacidade para o Trabalho (ICT) a fim de se identificarem os principais fatores que se relacionam com a capacidade para o trabalho dos profissionais de Enfermagem. Método: trata-se de um estudo bibliográfico, descritivo, do tipo revisão integrativa. Realizou-se a busca nas bases de dados MEDLINE via PUBMED, LILACS, na Biblioteca Virtual SciELO e no portal de Periódicos Capes. Incluíram-se os trabalhos originais na íntegra, produzidos nos últimos cinco anos, nos idiomas inglês, português e espanhol, disponíveis de forma gratuita e on-line. Apresentaram-se os resultados em forma de tabelas. Resultados: aponta-se que a amostra final resultou em 12 artigos, dos quais emergiram três categorias: Relação da carga horária de trabalho; Sobrecarga mental e Associação das doenças crônicas. Conclusão: evidencia-se que a carga horária de trabalho, a sobrecarga mental e as doenças osteomusculares são os principais fatores que interferem na capacidade para o trabalho e sua perda, além de serem determinantes fundamentais para a gênese de doenças ergonômicas. Fazem-se necessárias ações em saúde que auxiliem no desenvolvimento de estratégias a fim de se prevenir a perda da capacidade para o trabalho frente aos diversos contextos em que a Enfermagem está inserida.(AU)


Objective: to analyze the articles that used the Work Ability Index (WAI) in order to identify the main factors that relate to the work capacity of Nursing professionals. Method: this is a descriptive bibliographical study, of the integrative review type. The MEDLINE databases were searched through PUBMED, LILACS, the SciELO Virtual Library and the Capes Periodicals portal. The original works produced in the last five years in the English, Portuguese and Spanish languages, available free of charge and online, have been included. Results were presented in the form of tables. Results: it is pointed out that the final sample resulted in 12 articles, of which three categories emerged: Workload ratio; Mental Overload and Association of Chronic Diseases. Conclusion: it is evident that workload, mental overload and musculoskeletal diseases are the main factors that interfere in the ability to work and its loss, besides being fundamental determinants for the genesis of ergonomic diseases. Health actions are necessary that help in the development of strategies in order to prevent the loss of the capacity to work in the different contexts in which Nursing is inserted.(AU)


Objetivo: analizar los artículos que utilizaron el Índice de Capacidad para el Trabajo (ICT) a fin de identificar los principales factores que se relacionan con la capacidad para el trabajo de los profesionales de Enfermería. Método: se trata de un estudio bibliográfico, descriptivo, del tipo revisión integrativa. Se realizó la búsqueda en las bases de datos MEDLINE vía PUBMED, LILACS, en la Biblioteca Virtual SciELO y en el portal de Periódicos Capes. Se incluyó obras originales en su totalidad, producidos en los últimos cinco años, en inglés, portugués y español, disponibles de forma gratuita y en línea. Se presentaron los resultados en forma de tablas. Resultados: se señala que la muestra final resultó en 12 artículos, de los cuales surgieron tres categorías: Relación de la carga horaria de trabajo; Sobrecarga mental y Asociación de las enfermedades crónicas. Conclusión: se evidencia que la carga horaria de trabajo, la sobrecarga mental y las enfermedades osteomusculares son los principales factores que interfieren en la capacidad para el trabajo y su pérdida, además de ser determinantes fundamentales para la génesis de enfermedades ergonómicas. Se hacen necesarias acciones en salud que ayuden en el desarrollo de estrategias a fin de prevenir la pérdida de la capacidad para el trabajo frente a los diversos contextos en que la Enfermería está inserta.(AU)


Subject(s)
Humans , Male , Female , Work Capacity Evaluation , Work Hours , Occupational Health , Workload , Occupational Stress , Nursing, Team , Cumulative Trauma Disorders , Epidemiology, Descriptive , MEDLINE , LILACS
17.
Rev. enferm. UFPE on line ; 13: [1-11], 2019. ilus, tab, graf
Article in Portuguese | BDENF - Nursing | ID: biblio-1052565

ABSTRACT

Objetivo: identificar as evidências sobre as estratégias das equipes multiprofissionais para minimizar a infecção da corrente sanguínea relacionada ao manuseio do cateter venoso central. Método: trata-se de um estudo bibliográfico, descritivo, tipo revisão integrativa. Realizou-se a busca na BVS, na base de dados MEDLINE, na Biblioteca Virtual SciELO e no Portal CAPES. Incluíram-se trabalhos na íntegra, De 2014 a 2018, em inglês, português e espanhol. Apresentaramse os resultados em forma de figuras, seguida da análise descritiva de duas categorias: adesão da equipe multiprofissional às medidas de prevenção e bundles na redução das infecções da corrente sanguínea. Resultados: aponta-se que chegou à amostra de 11 artigos. Concentraram-se os achados, quanto ao ano e número de estudos, em sua maioria, de 2017 (45%), seguido de 2015 e 2016 (18%) e 2014 e 2018 (9%); quanto ao delineamento, houve maior prevalência, estudos observacionais, quase-experimental e transversal (18%), seguidos de ensaios clínicos randomizados, revisão sistemática, longitudinal e quantitativo (9%). Conclusão: conclui-se que os achados apresentaram os cuidados e manuseio com CVC mais recentes encontrados na literatura pesquisada.(AU)


Objective: to identify evidence on the strategies of multidisciplinary teams to minimize bloodstream infection related to central venous catheter handling. Method: this is a bibliographic, descriptive, integrative review study. The search was performed in the VHL, in the MEDLINE database, in the SciELO Virtual Library and in the CAPES Portal. Full papers were included, from 2014 to 2018, in English, Portuguese and Spanish. The results were presented as figures, followed by a descriptive analysis of two categories: adherence of the multiprofessional team to prevention measures and bundles to reduce bloodstream infections. Results: it is pointed that reached the sample of 11 articles. The findings were concentrated in terms of year and number of studies, mostly 2017 (45%), followed by 2015 and 2016 (18%) and 2014 and 2018 (9%); Regarding the design, there was a higher prevalence, observational, quasi-experimental and crosssectional studies (18%), followed by randomized clinical trials, systematic, longitudinal and quantitative review (9%). Conclusion: it is concluded that the findings presented the most recent care and handling with CVC found in the literature. (AU)


Objetivo: identificar evidencia sobre las estrategias de equipos multiprofesionales para minimizar la infección de la corriente sanguínea relacionada con el manejo del catéter venoso central. Método: este es un estudio de revisión bibliográfico, descriptivo, integrador. La búsqueda se realizó en la BVS, en la base de datos MEDLINE, en la Biblioteca Virtual SciELO y en el Portal CAPES. Se incluyeron documentos completos, de 2014 a 2018, en inglés, portugués y español. Los resultados se presentaron en forma de figuras, seguidos de un análisis descriptivo de dos categorías: adhesión del equipo multiprofesional a medidas de prevención y bundles para reducir las infecciones de la corriente sanguínea. Resultados: se señala que alcanzó la muestra de 11 artículos. Los hallazgos se concentraron en términos de año y número de estudios, principalmente 2017 (45%), seguidos de 2015 y 2016 (18%) y 2014 y 2018 (9%); en cuanto al diseño, hubo una mayor prevalencia, estudios observacionales, cuasi experimentales y transversales (18%), seguidos de ensayos clínicos aleatorios, revisión sistemática, longitudinal y cuantitativa (9%). Conclusión: se concluye que los hallazgos presentaron la atención y el manejo más recientes con CVC encontrados en la literatura investigada.(AU)


Subject(s)
Humans , Male , Female , Patient Care Team , Blood Circulation , Cross Infection , Catheter-Related Infections , Catheter-Related Infections/prevention & control , Patient Safety , Central Venous Catheters , Hospitalization , Epidemiology, Descriptive , MEDLINE
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