ABSTRACT
Background: Periodontal disease (PD) is the most common disease of the oral cavity in cats and dogs, and it affects up to 80% of these animals. PD begins with the accumulation of bacteria on the surface of the teeth, and it poses a risk for the health of pets. Research on PD in dogs has focused on the identification and characterization of bacterial communities present in the oral cavity. Porphyromonas gingivalis is highly prevalent in the oral cavity. Therefore, the aim of this study was to detect P. gingivalis before and after dental eruption in 15 English bulldog newborn puppies, hoping to contribute to early guidance of oral hygiene management and prevent future PD.Materials, Methods & Results: Fifteen English bulldog newborn puppies were used in this study. Two groups (G1 and G2) were formed with eight and seven puppies, respectively. Oral swab samples were taken from the maxillary incisor region of animals from G1 and G2 10 days after birth (T10). At this moment, the clinical evaluation of the oral cavity showed healthy gums with a thin, shiny, pinkish, and firm margin, without any odor or granular appearance, and with no tooth eruption. On postnatal day 25 (T25), a subgingival sample was collected with a Gracey curette from the maxillary incisors; the oral cavity examination revealed healthy gums and presence of gingival sulcus. Bilateral subgingival samples were als
ABSTRACT
Background: Periodontal disease (PD) is the most common disease of the oral cavity in cats and dogs, and it affects up to 80% of these animals. PD begins with the accumulation of bacteria on the surface of the teeth, and it poses a risk for the health of pets. Research on PD in dogs has focused on the identification and characterization of bacterial communities present in the oral cavity. Porphyromonas gingivalis is highly prevalent in the oral cavity. Therefore, the aim of this study was to detect P. gingivalis before and after dental eruption in 15 English bulldog newborn puppies, hoping to contribute to early guidance of oral hygiene management and prevent future PD.Materials, Methods & Results: Fifteen English bulldog newborn puppies were used in this study. Two groups (G1 and G2) were formed with eight and seven puppies, respectively. Oral swab samples were taken from the maxillary incisor region of animals from G1 and G2 10 days after birth (T10). At this moment, the clinical evaluation of the oral cavity showed healthy gums with a thin, shiny, pinkish, and firm margin, without any odor or granular appearance, and with no tooth eruption. On postnatal day 25 (T25), a subgingival sample was collected with a Gracey curette from the maxillary incisors; the oral cavity examination revealed healthy gums and presence of gingival sulcus. Bilateral subgingival samples were als
ABSTRACT
Background: Periodontal disease (PD) is the most common disease of the oral cavity in cats and dogs, and it affects up to 80% of these animals. PD begins with the accumulation of bacteria on the surface of the teeth, and it poses a risk for the health of pets. Research on PD in dogs has focused on the identification and characterization of bacterial communities present in the oral cavity. Porphyromonas gingivalis is highly prevalent in the oral cavity. Therefore, the aim of this study was to detect P. gingivalis before and after dental eruption in 15 English bulldog newborn puppies, hoping to contribute to early guidance of oral hygiene management and prevent future PD.Materials, Methods & Results: Fifteen English bulldog newborn puppies were used in this study. Two groups (G1 and G2) were formed with eight and seven puppies, respectively. Oral swab samples were taken from the maxillary incisor region of animals from G1 and G2 10 days after birth (T10). At this moment, the clinical evaluation of the oral cavity showed healthy gums with a thin, shiny, pinkish, and firm margin, without any odor or granular appearance, and with no tooth eruption. On postnatal day 25 (T25), a subgingival sample was collected with a Gracey curette from the maxillary incisors; the oral cavity examination revealed healthy gums and presence of gingival sulcus. Bilateral subgingival samples were als
ABSTRACT
Background: Periodontal disease (PD) is the most common disease of the oral cavity in cats and dogs, and it affects up to 80% of these animals. PD begins with the accumulation of bacteria on the surface of the teeth, and it poses a risk for the health of pets. Research on PD in dogs has focused on the identification and characterization of bacterial communities present in the oral cavity. Porphyromonas gingivalis is highly prevalent in the oral cavity. Therefore, the aim of this study was to detect P. gingivalis before and after dental eruption in 15 English bulldog newborn puppies, hoping to contribute to early guidance of oral hygiene management and prevent future PD.Materials, Methods & Results: Fifteen English bulldog newborn puppies were used in this study. Two groups (G1 and G2) were formed with eight and seven puppies, respectively. Oral swab samples were taken from the maxillary incisor region of animals from G1 and G2 10 days after birth (T10). At this moment, the clinical evaluation of the oral cavity showed healthy gums with a thin, shiny, pinkish, and firm margin, without any odor or granular appearance, and with no tooth eruption. On postnatal day 25 (T25), a subgingival sample was collected with a Gracey curette from the maxillary incisors; the oral cavity examination revealed healthy gums and presence of gingival sulcus. Bilateral subgingival samples were als
ABSTRACT
Background: Periodontal disease (PD) is the most common disease of the oral cavity in cats and dogs, and it affects up to 80% of these animals. PD begins with the accumulation of bacteria on the surface of the teeth, and it poses a risk for the health of pets. Research on PD in dogs has focused on the identification and characterization of bacterial communities present in the oral cavity. Porphyromonas gingivalis is highly prevalent in the oral cavity. Therefore, the aim of this study was to detect P. gingivalis before and after dental eruption in 15 English bulldog newborn puppies, hoping to contribute to early guidance of oral hygiene management and prevent future PD.Materials, Methods & Results: Fifteen English bulldog newborn puppies were used in this study. Two groups (G1 and G2) were formed with eight and seven puppies, respectively. Oral swab samples were taken from the maxillary incisor region of animals from G1 and G2 10 days after birth (T10). At this moment, the clinical evaluation of the oral cavity showed healthy gums with a thin, shiny, pinkish, and firm margin, without any odor or granular appearance, and with no tooth eruption. On postnatal day 25 (T25), a subgingival sample was collected with a Gracey curette from the maxillary incisors; the oral cavity examination revealed healthy gums and presence of gingival sulcus. Bilateral subgingival samples were als
ABSTRACT
Background: Periodontal disease (PD) is the most common disease of the oral cavity in cats and dogs, and it affects up to 80% of these animals. PD begins with the accumulation of bacteria on the surface of the teeth, and it poses a risk for the health of pets. Research on PD in dogs has focused on the identification and characterization of bacterial communities present in the oral cavity. Porphyromonas gingivalis is highly prevalent in the oral cavity. Therefore, the aim of this study was to detect P. gingivalis before and after dental eruption in 15 English bulldog newborn puppies, hoping to contribute to early guidance of oral hygiene management and prevent future PD.Materials, Methods & Results: Fifteen English bulldog newborn puppies were used in this study. Two groups (G1 and G2) were formed with eight and seven puppies, respectively. Oral swab samples were taken from the maxillary incisor region of animals from G1 and G2 10 days after birth (T10). At this moment, the clinical evaluation of the oral cavity showed healthy gums with a thin, shiny, pinkish, and firm margin, without any odor or granular appearance, and with no tooth eruption. On postnatal day 25 (T25), a subgingival sample was collected with a Gracey curette from the maxillary incisors; the oral cavity examination revealed healthy gums and presence of gingival sulcus. Bilateral subgingival samples were als
ABSTRACT
Osteoarthritis (OA) is the most common joint disease in both humans and animals, and it results in movement restriction and pain at the affected area. This disorder affects more than 25% of people over 60 years of age, and it is considered universal for 70-year-old people. OA is estimated to affect over 20% of the canine population from the United States of America. The present study aimed to evaluate the treatment of rats that were surgically induced to OA using two different drug therapies, one with pentosan polysulfate, one with betamethasone, and one with chondroitin sulfate/ glucosamine. In order to produce joint disease, the cranial cruciate ligament was surgically transected. Animals were kept and treated for eight days after surgery and were assessed via both radiographies and tomographies taken before surgery and eight weeks later. All animals were euthanized having both macroscopic and microscopic analysis performed to evaluate the disorder progression and therapeutic action. Macroscopic analysis showed lesion in the knees subjected to OA induction. The untreated animals presented major lesions whereas the treated ones presented mild to moderate lesions. In conclusion, pentosan polysulfate is recommendable for the treatment of iatrogenic joint lesions in rats since the other treatments showed no significant difference.
A osteoartrite (OA) é a doença articular mais comum em humanos e animais, o que ocasiona restrição de movimentos e dor, na região acometida. Tal enfermidade afeta mais de 25% dos humanos acima de 60 anos e, aos 70 anos, ela é considerada universal. Estima-se que nos Estados Unidos da América, 20% ou mais da população canina é acometida pela OA. O presente estudo tem como finalidade avaliar a terapia medicamentosa (polisulfato de pentosano, betametasona e sulfato de condroitina/glucosamina), em um modelo experimental de OA cirurgicamente induzido, em ratos. A doença articular foi promovida pela transecção cirúrgica do ligamento cruzado cranial, sendo que, após o procedimento cirúrgico, os animais foram mantidos e tratados por oito semanas. Foi realizada avaliação radiográfica e tomográfica antes e oito semanas após a indução da osteoartrite. Todos os animais foram submetidos à eutanásia para análise macroscópica e microscópica, que foram realizadas para avaliar a progressão da enfermidade e a ação terapêutica. Na análise macroscópica foi observadas lesões nos joelhos submetidos à indução OA. Os animais não tratados apresentaram lesões graves enquanto que, os animais tratados apresentaram lesões leves a moderadas. Concluiu-se que o polissulfato de pentosano é eficiente no tratamento de lesões articulares iatrogênicas de ratos, uma vez que outros tratamentos não mostraram qualque
ABSTRACT
Osteoarthritis (OA) is the most common joint disease in both humans and animals, and it results in movement restriction and pain at the affected area. This disorder affects more than 25% of people over 60 years of age, and it is considered universal for 70-year-old people. OA is estimated to affect over 20% of the canine population from the United States of America. The present study aimed to evaluate the treatment of rats that were surgically induced to OA using two different drug therapies, one with pentosan polysulfate, one with betamethasone, and one with chondroitin sulfate/ glucosamine. In order to produce joint disease, the cranial cruciate ligament was surgically transected. Animals were kept and treated for eight days after surgery and were assessed via both radiographies and tomographies taken before surgery and eight weeks later. All animals were euthanized having both macroscopic and microscopic analysis performed to evaluate the disorder progression and therapeutic action. Macroscopic analysis showed lesion in the knees subjected to OA induction. The untreated animals presented major lesions whereas the treated ones presented mild to moderate lesions. In conclusion, pentosan polysulfate is recommendable for the treatment of iatrogenic joint lesions in rats since the other treatments showed no significant difference.
A osteoartrite (OA) é a doença articular mais comum em humanos e animais, o que ocasiona restrição de movimentos e dor, na região acometida. Tal enfermidade afeta mais de 25% dos humanos acima de 60 anos e, aos 70 anos, ela é considerada universal. Estima-se que nos Estados Unidos da América, 20% ou mais da população canina é acometida pela OA. O presente estudo tem como finalidade avaliar a terapia medicamentosa (polisulfato de pentosano, betametasona e sulfato de condroitina/glucosamina), em um modelo experimental de OA cirurgicamente induzido, em ratos. A doença articular foi promovida pela transecção cirúrgica do ligamento cruzado cranial, sendo que, após o procedimento cirúrgico, os animais foram mantidos e tratados por oito semanas. Foi realizada avaliação radiográfica e tomográfica antes e oito semanas após a indução da osteoartrite. Todos os animais foram submetidos à eutanásia para análise macroscópica e microscópica, que foram realizadas para avaliar a progressão da enfermidade e a ação terapêutica. Na análise macroscópica foi observadas lesões nos joelhos submetidos à indução OA. Os animais não tratados apresentaram lesões graves enquanto que, os animais tratados apresentaram lesões leves a moderadas. Concluiu-se que o polissulfato de pentosano é eficiente no tratamento de lesões articulares iatrogênicas de ratos, uma vez que outros tratamentos não mostraram qualque
ABSTRACT
Introdução: A ocorrência de convulsões durante a anestesia em pacientes veterinários raramente é relatada na literatura, tornando desconhecida a incidência de tais eventos. Várias drogas comumente utilizadas na anestesiologia veterinária mostram-se capazes de induzir a atividade epilética, sendo, portanto, indicada a associação entre fármacos na tentativa de minimizar efeitos adversos. O presente relato descreve o caso de um canino jovem, raça Lhasa Apso, com mioglobinúria após convulsão durante anestesia com cetamina.Caso: Um canino, macho, com um ano de idade, raça Lhasa Apso foi encaminhado ao centro cirúrgico do Hospital Veterinário da Universidade Federal de Mato Grosso, em Cuiabá, para correção de hérnia umbilical. Animal hígido, sem relato de doenças anteriores e sem alterações no exame físico e laboratorial. Como medicação pré-anestésica, foi utilizada a associação de cetamina (8 mg/kg) com midazolam (0,5 mg/kg) por via intramuscular. A indução anestésica foi feita com propofol (6 mg/kg) e a manutenção inalatória com halotano. Após anestesia geral, o animal apresentou crises convulsivas que foram controladas com diazepam (1 mg/kg, intravenoso). Durante grande parte do procedimento cirúrgico, o animal apresentou apnéia. Com o término da cirurgia, o cão apresentou uma recuperação anestésica com excitabilidade, salivação, vocalização, taquicardia, além de crises convulsiva
ABSTRACT
Introdução: A ocorrência de convulsões durante a anestesia em pacientes veterinários raramente é relatada na literatura, tornando desconhecida a incidência de tais eventos. Várias drogas comumente utilizadas na anestesiologia veterinária mostram-se capazes de induzir a atividade epilética, sendo, portanto, indicada a associação entre fármacos na tentativa de minimizar efeitos adversos. O presente relato descreve o caso de um canino jovem, raça Lhasa Apso, com mioglobinúria após convulsão durante anestesia com cetamina.Caso: Um canino, macho, com um ano de idade, raça Lhasa Apso foi encaminhado ao centro cirúrgico do Hospital Veterinário da Universidade Federal de Mato Grosso, em Cuiabá, para correção de hérnia umbilical. Animal hígido, sem relato de doenças anteriores e sem alterações no exame físico e laboratorial. Como medicação pré-anestésica, foi utilizada a associação de cetamina (8 mg/kg) com midazolam (0,5 mg/kg) por via intramuscular. A indução anestésica foi feita com propofol (6 mg/kg) e a manutenção inalatória com halotano. Após anestesia geral, o animal apresentou crises convulsivas que foram controladas com diazepam (1 mg/kg, intravenoso). Durante grande parte do procedimento cirúrgico, o animal apresentou apnéia. Com o término da cirurgia, o cão apresentou uma recuperação anestésica com excitabilidade, salivação, vocalização, taquicardia, além de crises convulsiva