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1.
Rev. Soc. Bras. Med. Trop ; 38(5): 391-395, set.-out. 2005. tab
Article in Portuguese | LILACS | ID: lil-409472

ABSTRACT

Com o objetivo de isolar e identificar os sorotipos de enterovírus, agentes etiológicos mais freqüentes da síndrome de meningite asséptica, foram estudadas amostras de líquor de pacientes da unidade de saúde de referência da Cidade de Belém-PA, do período de março de 2002 a março de 2003. As amostras foram inoculadas em cultivos celulares RD e HEp-2, e as positivas identificadas por neutralização ou imunofluorescência indireta. De 249 amostras, 33 (13,2 por cento) foram positivas sendo 57,6 por cento (n=19) em pacientes menores de 11 anos (p<0,03) e predominantemente (72,7 por cento) naqueles do sexo masculino (p<0,008). Os sorotipos isolados foram: Echovírus 30 (n=31), Coxsackievírus B5 (n=1) e Echovírus 30 e 4. Em conclusão, estudos deste tipo servem também para melhor compor o quadro nacional, ainda pouco definido, sobre os agentes enterovirais mais prevalentes em casos de SMA.


Subject(s)
Humans , Male , Female , Infant , Child, Preschool , Child , Adolescent , Adult , Middle Aged , Enterovirus Infections/virology , Enterovirus/classification , Meningitis, Aseptic/virology , Cross-Sectional Studies , Enterovirus Infections/classification , Enterovirus/isolation & purification , Meningitis, Aseptic/classification
2.
Rev Soc Bras Med Trop ; 38(5): 391-5, 2005.
Article in Portuguese | MEDLINE | ID: mdl-16172753

ABSTRACT

With the objective of isolating and identifying enteroviral serotypes, which are the most frequent etiologic agents of aseptic meningitis syndrome, cerebrospinal fluid samples were studied from patients referred to the health unit in the City of Belém (State of Pará, Brazil), from March 2002 to March 2003. The samples were inoculated in RD and HEp-2 cells line, and the positive were identified by neutralization test or indirect immunofluorescence. Out of 249 samples, 33 (13.2%) were positive 57.6% (n = 19) in patients under 11 years of age (p < 0.03) and predominantly (72.7%) in males (p < 0.008). The serotypes isolated were: Echovirus 30 (n = 31), Coxsackievirus B5 (n = 1) and Echovirus 30 and 4. In conclusion, this type of study also serves to determine the national picture, which is still little defined, regarding the most prevalent viral agents in AMS cases.


Subject(s)
Enterovirus Infections/virology , Enterovirus/classification , Meningitis, Aseptic/virology , Adolescent , Adult , Aged , Child , Child, Preschool , Cross-Sectional Studies , Enterovirus/isolation & purification , Enterovirus Infections/cerebrospinal fluid , Female , Humans , Infant , Male , Meningitis, Aseptic/cerebrospinal fluid , Middle Aged
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