[Cervix adenocarcinoma in a virgin patient with negative human papillomavirus]. / Adenocarcinoma de cérvix en una paciente virgen con virus del papiloma humano negativo.

Cervical cancer in virgin women is extremely rare. We present the case of a 36-year-old patient without any type of sexual contact with sensa- tion of lump in external genitalia referring only irregular bleeding in the previous two months, finding in vaginal examination an indurated mass in vaginal introitus with result in the biopsy of adenosquamous adenocarcinoma. The evolution of the tumor was very aggressive in spite of trying palliative chemotherapy, and patient died two months after of diagnosis with lung, liver and brain metastases. Cervical human papil- lomavirus testing was negative. What unusual of these cases does not justify the cytology as the only method of screening for cervical cancer.

[Atypical presentation of a clinical case of giant cell arteritis]. / Presentación atípica de un caso de arteritis de células gigantes.

We present a very unusual clinical case of giant cell arteritis with uterus involvement, in a women of 66 years old, that began clinical features of pain and functional limitation of shoulders and hip 3 mouth before been operated of uterus prolapse with hysterectomy. Biopsy of uterus found affected arterial vesels with wall sclerosis and granulomatous inflamation with giant cells, without necrosis, involving media and perivascular portions suggesting giant cell arteritis. In a previous reports review, we only found ten similar clinical cases. In that cases, clinical features were no suggestif of the disease. Although the well known tendency of arteritis to involve some specific vascular areas, the case we present is an example of the systemic course of the disease and his difficulty to diagnose.

Presentación atípica de un caso de arteritis de células gigantes / Atypical presentation of a clinical case of a giant cell arteritis

Presentamos un caso muy poco frecuente de arteritis de células gigantes con afectación uterina, en una mujer de 66 años de edad, que inició clínica de dolor y limitación funcional en cintura escapular y pelviana 3 meses antes de ser operada de histerectomía por prolapso uterino. En la biopsia de cuerpo uterino se detecta vasos arteriales con esclerosis de pared e inflamación granulomatosa con células gigantes, sin necrosis, afectando capas media y perivascular, compatible con arteritis de células gigantes. En la revisión de la literatura tan solo hemos encontrado la publicación de una decena de casos similares. En ellos la clínica tampoco hacía sospechar la presencia de la enfermedad. A pesar del tropismo bien conocido de la arteritis de células gigantes por ciertos territorios vasculares, el caso que presentamos muestra el carácter sistémico de la enfermedad y la dificultad diagnóstica

We present a very unusual clinical case of giant cell arteritis with uterus involvement, in a women of 66 years old, that began clinical features of pain and functional limitation of shoulders and hip 3 mouth before been operated of uterus prolapse with hysterectomy. Biopsy of uterus found affected arterial vesels with wall sclerosis and granulomatous inflamation with giant cells, without necrosis, involving media and perivascular portions suggesting giant cell arteritis. In a previous reports review, we only found ten similar clinical cases. In that cases, clinical features were no suggestif of the disease. Althougt the well known tendency of arteritis to involve some specific vascular areas, the case we present is an example of the systemic course of the disease and his dificulty to diagnose