ABSTRACT
Angiosarcomas are rare tumors that usually entail a poor prognosis because of extensive invasiveness and high rates of distant metastasis. Gastrointestinal tract involvement is uncommon but may cause digestive bleeding. A definitive diagnosis requires histological and immunohistochemical testing. Metastatic lesions to the gut usually have a typical morphology, which must be identified in order to avoid delay in the diagnosis and potential treatment of this malignant condition.
Subject(s)
Hemangiosarcoma , Humans , Hemangiosarcoma/diagnosis , Hemangiosarcoma/pathology , Hemangiosarcoma/therapy , Aorta/pathology , BiopsyABSTRACT
BACKGROUND: Anastomotic dehiscence is a common complication of anterior resection. In this work, we evaluate the management of the pelvic cavity after low rectal resection using vacuum closure (VAC) with a gastroscope, and we establish factors that determine the success of closure and analyzed the rate of ileostomy closure after leakage was resolved. PATIENTS AND METHODS: This is a descriptive case series analysis conducted at a tertiary hospital. Twenty-two patients with low colorectal anastomosis leakage or opening of the rectal stump after anterior resection for rectal cancer were included. They were treated with VAC therapy. RESULTS: The total number of endoscopic sessions was 3.1 ± 1.9 in the anterior resection with anastomosis group and 3.2 ± 1.8 in the Hartmann group. In 11 patients the therapy was administered in an ambulatory setting. The mean time to healing was 22.3 ± 14.7 days. Full resolution was achieved in 19 patients (followed-up 1 year). Ileostomy closure was carried out in 5 patients (38.46%) during follow-up. None of these patients showed leakage signs. Statistically significant differences were obtained depending on the onset of therapy, with better results in patients who underwent earlier vacuum-assisted therapy (before the sixth week after initial surgery), P = .041. CONCLUSIONS: VAC therapy is an alternative to surgery that can be safely administered in an ambulatory setting. Early administration in the 6 weeks following surgery is an independent predictive factor for successful closure; however, colonic transit was only recovered in a small percentage of patients.
Subject(s)
Anastomotic Leak/surgery , Negative-Pressure Wound Therapy/methods , Rectal Neoplasms/surgery , Aged , Cohort Studies , Female , Humans , Male , Middle Aged , Surgical Wound Dehiscence/surgeryABSTRACT
No disponible
Subject(s)
Adult , Female , Humans , Male , Middle Aged , Young Adult , Listeriosis/diagnosis , Listeria monocytogenes/pathogenicity , Tumor Necrosis Factor-alpha/antagonists & inhibitors , Irritable Bowel Syndrome/drug therapy , Disease Susceptibility/chemically induced , Immunosuppressive Agents/adverse effectsSubject(s)
Azathioprine/therapeutic use , Common Variable Immunodeficiency/complications , Crohn Disease/drug therapy , Immunosuppressive Agents/therapeutic use , Adrenal Cortex Hormones/therapeutic use , Azathioprine/adverse effects , Campylobacter Infections/complications , Crohn Disease/complications , Gastritis/complications , Gastritis/drug therapy , Helicobacter Infections/complications , Helicobacter Infections/drug therapy , Humans , Immunoglobulins, Intravenous/therapeutic use , Immunosuppressive Agents/adverse effects , Male , Middle AgedSubject(s)
Bacteremia/etiology , Colitis, Ulcerative/drug therapy , Crohn Disease/drug therapy , Immunosuppressive Agents/adverse effects , Listeriosis/etiology , Bacteremia/microbiology , Colitis, Ulcerative/complications , Colitis, Ulcerative/immunology , Crohn Disease/complications , Crohn Disease/immunology , Disease Susceptibility , Humans , Immunocompromised Host , Immunosuppressive Agents/therapeutic use , Intestinal Mucosa/microbiology , Intestinal Mucosa/pathology , Male , Meningitis, Listeria/etiology , Young AdultABSTRACT
No disponible
Subject(s)
Humans , Female , Adult , Anemia, Hemolytic, Autoimmune/drug therapy , Antibodies, Monoclonal/pharmacokinetics , Colitis, Ulcerative/complications , Inflammatory Bowel Diseases/drug therapySubject(s)
Colitis, Ulcerative/complications , Cytomegalovirus Infections/etiology , Cytomegalovirus/pathogenicity , Postoperative Complications , Pouchitis/etiology , Adult , Colitis, Ulcerative/therapy , Colitis, Ulcerative/virology , Cytomegalovirus Infections/diagnosis , Humans , Male , Proctocolectomy, Restorative , PrognosisABSTRACT
No disponible
Subject(s)
Humans , Thalidomide/therapeutic use , Gastrointestinal Hemorrhage/surgery , Proctitis/surgery , Argon , Endoscopy, Gastrointestinal/methods , Radiation Injuries/surgery , Radiotherapy/adverse effectsABSTRACT
No disponible