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Epilepsy Behav ; 24(1): 126-30, 2012 May.
Article in English | MEDLINE | ID: mdl-22504057

ABSTRACT

We studied the temporal resolution ability in patients with refractory complex partial seizures and mesial temporal sclerosis (MTS) using Gaps-In-Noise (GIN) test in a prospective cross-sectional study. Thirteen patients with right MTS (age: 31±7.67 years; M:F=8:5) and 13 patients with left MTS (age: 25.76±8.26 years; M:F=9:4) having normal hearing and mini-mental state examination (MMSE) score of >23/30 were recruited. Fifty healthy volunteers (26.3±5.17 years; M:F=28:22) formed the control group. Gaps-In-Noise test demonstrated impaired temporal resolution: 69.2% of patients with right MTS (RMTS) and 76.9% of patients with left MTS (LMTS) had abnormal scores in the right ear for gap detection threshold (GDT) measure. Similarly, 53.8% of patients in the RMTS group and 76.9% of patients in the LMTS group had abnormal scores in the left ear. In percentage of correct identification (PCI), 46.1% of patients with RMTS and 69.2% of patients with LMTS had poorer scores in the right ear, whereas 46.1% of patients with RMTS and 61.5% of patients with LMTS had poorer scores in the left ear. Both patient groups, viz., RMTS and LMTS, demonstrated bilateral temporal resolution deficits.


Subject(s)
Epilepsy, Complex Partial/complications , Epilepsy, Complex Partial/pathology , Language Development Disorders/etiology , Temporal Lobe/pathology , Acoustic Stimulation/methods , Adolescent , Adult , Analysis of Variance , Cross-Sectional Studies , Female , Functional Laterality , Humans , Language Development Disorders/diagnosis , Male , Neuropsychological Tests , Prospective Studies , Psychophysics , Sclerosis/complications , Sclerosis/pathology , Sensory Thresholds , Signal Detection, Psychological , Young Adult
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