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J Dairy Res ; 88(1): 64-68, 2021 Feb.
Article in English | MEDLINE | ID: mdl-33731240

ABSTRACT

Our objective was to evaluate the efficacy of intramammary administration, at drying-off, of a Panax ginseng extract (PGe) combined with cephalexin (Ceph) on the post-calving bacteriological cure rate of pre-existing intramammary infections (IMI) and on the occurrence of new IMI during the dry period. In addition, milk yield and somatic cell count (SCC) in the post-treatment lactation were evaluated. One hundred and eight late-lactation cows were randomly divided into two experimental groups and were treated at drying-off with Ceph alone or PGe combined with Ceph.Cure rates for IMI present at drying-off were similar for both treatments (OR = 0.95, 95% CI = 0.33-2.74). Cure rates for Staphylococcus aureus were lower (OR = 15.4, 95% CI = 1.66-142.52) in quarters treated with PGe + Ceph than in those treated with Ceph alone. Intramammary infusion of PGe + Ceph at drying-off had no effect on preventing new dry period IMI (OR = 0.75, 95% CI = 0.38-1.51), compared with infusion of Ceph alone. Milk production and SCC in the ensuing lactation were not affected by PGe + Ceph treatment. In conclusion, addition of PGe to dry cow therapy did not show any advantage over the use of dry cow therapy alone.


Subject(s)
Anti-Bacterial Agents/administration & dosage , Cephalexin/administration & dosage , Mastitis, Bovine/drug therapy , Panax/chemistry , Plant Extracts/administration & dosage , Animals , Cattle , Cell Count/veterinary , Drug Therapy, Combination/veterinary , Female , Lactation , Mammary Glands, Animal/drug effects , Mastitis, Bovine/prevention & control , Milk/cytology , Staphylococcal Infections/drug therapy , Staphylococcal Infections/veterinary , Staphylococcus aureus
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