1.
Am J Obstet Gynecol
; 119(5): 596-602, 1974 Jul 01.
Article
in English
| MEDLINE
| ID: mdl-4857791
2.
Science
; 160(3823): 81-2, 1968 Apr 05.
Article
in English
| MEDLINE
| ID: mdl-5689266
ABSTRACT
Incubation of deamino-oxytocin with plasma obtained from women in labor reduced the potency of this analog of oxytocin when assayed on an isolated strip of mammary gland taken from a lactating rat. Plasmas of nonpregnant women had no detectable effect on this activity of deamino-oxytocin, and the effect of plasmas from women just previous to the beginning of labor was not significant. The original. activities of the incubated deamino-oxytocin solutions could be restored by treatment with hydrogen peroxide. The inactivation may be caused by reductive cleavage of the disulfide bridge of deamino-oxytocin, this bridge being reformed by oxidation.
Subject(s)
Blood , Oxytocics/analysis , Oxytocin , Animals , Biological Assay , Female , Humans , Hydrogen Peroxide , In Vitro Techniques , Labor, Obstetric , Lactation , Mammary Glands, Animal/drug effects , Pregnancy , Rats , Sulfides
3.
An Fac Med Univ Repub Montev Urug
; 51(1): 56-62, 1966.
Article
in Spanish
| MEDLINE
| ID: mdl-6015092