ABSTRACT
CASOS CLÍNICOS: Para el manejo del herpes zóster oftálmico (HZO), se han descrito diferentes tratamientos. Sin embargo, la evolución de estos pacientes es usualmente prolongada y muchos de ellos desarrollan neuritis postherpética (NPH). En el presente trabajo, se presentan 3 casos clínicos, en los cuales, mediante una inyección preauricular de una mezcla de betametasona de depósito combinada con aciclovir se obtuvo una importante mejoría clínica y sintomática. Adicionalmente, no se reportó el desarrollo de NPH. DISCUSIÓN: La inyección preauricular de betametasona de depósito y aciclovir podría constituir una buena alternativa para el manejo del HZO
CLINICAL CASES: Several treatments have been described for the management of patients with herpes zoster ophthalmicus (HZO). However, the progress of these patients is usually slow, and many of them develop postherpetic neuritis (PHN). In the present paper, three clinical cases are presented, in which a significant symptomatic improvement was obtained by using a preauricular injection of a mixture of betamethasone depot combined with acyclovir. PHN did not develop in any of them. DISCUSSION: The preauricular injection of betamethasone depot and acyclovir could be a good alternative for the management of HZO
Subject(s)
Female , Humans , Male , Herpes Zoster Ophthalmicus/metabolism , Herpes Zoster Ophthalmicus/pathology , Asepsis/methods , Facial Nerve/abnormalities , Facial Nerve/pathology , Pharmaceutical Preparations/administration & dosage , Pharmaceutical Preparations/metabolism , Herpes Zoster Ophthalmicus/complications , Herpes Zoster Ophthalmicus/surgery , Asepsis/instrumentation , Facial Nerve , Facial Nerve/surgery , Pharmaceutical Preparations , Pharmaceutical Preparations/supply & distributionABSTRACT
CLINICAL CASES: Several treatments have been described for the management of patients with herpes zoster ophthalmicus (HZO). However, the progress of these patients is usually slow, and many of them develop postherpetic neuritis (PHN). In the present paper, three clinical cases are presented, in which a significant symptomatic improvement was obtained by using a preauricular injection of a mixture of betamethasone depot combined with acyclovir. PHN did not develop in any of them. DISCUSSION: The preauricular injection of betamethasone depot and acyclovir could be a good alternative for the management of HZO.
Subject(s)
Acyclovir/administration & dosage , Antiviral Agents/administration & dosage , Betamethasone/administration & dosage , Glucocorticoids/administration & dosage , Herpes Zoster Ophthalmicus/drug therapy , Acute Disease , Aged , Delayed-Action Preparations , Drug Therapy, Combination , Ear , Female , Humans , Injections , Male , Middle AgedABSTRACT
CASOS CLÍNICOS: La pinguecula es una lesión degenerativa que suele ser asintomática, excepto cuando se produce alguna reacción inflamatoria asociada. Se presentan dos casos clínicos de pacientes que cursan con pinguecula sintomática en los cuales se utilizó betametasona intralesional de depósito como tratamiento, obteniendo una mejoría clínica significativa. DISCUSIÓN: La administración de betametasona intralesional de depósito podría constituir una buena alternativa para el tratamiento de la pinguecula sintomática
CLINICAL CASE: The pinguecula is a degenerative lesion which is usually asymptomatic, except when it is associated with an inflammatory reaction. We present 2 clinical cases of patients that had symptomatic pinguecula, in which intra-lesional betamethasone in depot form was used as treatment, obtaining a significant clinical improvement. DISCUSSION: The administration of intra-lesional betamethasone in depot form may be a good alternative for the treatment of the symptomatic pinguecula
Subject(s)
Humans , Female , Infiltration-Percolation/analysis , Infiltration-Percolation/methods , Vision Disparity/genetics , Betamethasone/administration & dosage , Betamethasone/analysis , Infiltration-Percolation/classification , Vision Disparity/physiology , Betamethasone/classification , Pharmaceutical PreparationsABSTRACT
CLINICAL CASES: The pinguecula is a degenerative lesion which is usually asymptomatic, except when it is associated with an inflammatory reaction. We present 2 clinical cases of patients that had symptomatic pinguecula, in which intra-lesional betamethasone in depot form was used as treatment, obtaining a significant clinical improvement. DISCUSSION: The administration of intra-lesional betamethasone in depot form may be a good alternative for the treatment of the symptomatic pinguecula.
Subject(s)
Betamethasone/administration & dosage , Glucocorticoids/administration & dosage , Pinguecula/drug therapy , Adult , Female , Humans , Injections, Intralesional , Pinguecula/diagnosisABSTRACT
A rare complication of penetrating keratoplasty is incomplete removal of the host Descemet's membrane, which can progressively become opaque. Utilizing a Nd:YAG laser, we opened the opaque membrane, improving visual acuity from 20/400 to 20/100.
Subject(s)
Corneal Opacity/etiology , Descemet Membrane/surgery , Keratoplasty, Penetrating/adverse effects , Humans , Laser Therapy , Male , Middle Aged , Visual AcuityABSTRACT
We describe a technique and report a retrospective evaluation of myopic keratomileusis in situ. Surgery was performed on 32 eyes, with a mean follow-up time of 128.7 days (range 90 to 194 days). The average reduction of myopia was 8.48 diopters (D) when measured by refraction and 3.96 D by keratometry (minor axis). A statistically significant Pearson correlation coefficient of 0.49 (P = .01) was found between these two variables. Postoperative mean manifest spherical equivalent was -1.70 D (standard deviation 2.54 D). Mean cylinder correction increased -0.48 D (range -2.25 to 2.00 D). Uncorrected visual acuity improved after surgery in all eyes, but in 14 eyes the best corrected visual acuity diminished. Multiple regression model disclosed a limited predictability of the technique. Complications included diminution of best corrected visual acuity, under- and overcorrections, increase in keratometric astigmatism and cylinder correction, keratitis, delayed corneal epithelialization, interface amorphous deposits, monocular diplopia, interface epithelialization, and opacification. The most frustrating was an elusive postoperative cycloplegic refraction. In our hands, myopic keratomileusis in situ was not a technically safe, precise, and predictable technique for correction of myopia. Further improvement in the technique and equipment may provide better results.