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Miliary tuberculosis with indeterminate interferon gamma release assay results.
Nei, Takahito; Fujisawa, Yousuke; Izumi, Yuuki; Tetsuka, Akito; Arita, Yosie; Murata, Hiroshige; Sawai, Keisuke; Kitamura, Mitsunobu; Miyachi, Hideki; Hosokawa, Yusuke; Akutsu, Koichi; Yamamoto, Takeshi; Tanaka, Keiji; Shinoyama, Akihiro.
Intern Med ; 52(22): 2583-5, 2013.
Article in English | MEDLINE | ID: mdl-24240801

ABSTRACT

Recently, interferon gamma release assays (IGRAs) have become an important clinical tool for detecting latent tuberculosis. However, IGRA results may impede making a diagnosis. We herein present an interesting case of miliary tuberculosis with a nonspecific IGRA reaction due to hemophagocytosis.


Subject(s)
Interferon-gamma/biosynthesis , Tuberculosis, Miliary/diagnosis , Tuberculosis, Miliary/immunology , Antigens, Bacterial/administration & dosage , False Negative Reactions , Fatal Outcome , Humans , Male , Middle Aged , Mycobacterium tuberculosis/immunology , Phagocytosis , T-Lymphocytes/immunology
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