1.
Early Hum Dev
; 28(3): 215-22, 1992.
Article
in English
| MEDLINE
| ID: mdl-1592006
ABSTRACT
We provide evidence for the presence of arginine vasopressin (AVP) in human fetal and neonatal skeletal muscle using a combination of specific RIA, tangential flow ultrafiltration and reverse-phase HPLC separation. The IR-AVP concentrations are negatively correlated with gestational age (r = -0.75, P less than 0.0001) and range from 1 to 10 pmol/g wet wt at 15 weeks gestation to 0.04 pmol/g wet wt at term. This IR-AVP substance is of low molecular weight (less than 3000 mol. wt), elutes in the same position as standard AVP after HPLC separation and is detected by four different anti-AVP antisera.
Subject(s)
Arginine Vasopressin/biosynthesis , Fetus/physiology , Muscles/metabolism , Age Factors , Arginine Vasopressin/isolation & purification , Chromatography, High Pressure Liquid , Gestational Age , Humans , Radioimmunoassay
2.
Biochem Soc Trans
; 19(2): 175S, 1991 Apr.
Article
in English
| MEDLINE
| ID: mdl-1889560