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Survey of Klebsiella pneumoniae producing extended-spectrum beta-lactamases: prevalence of TEM-3 and first identification of TEM-26 in France.

Soilleux, M J; Morand, A M; Arlet, G J; Scavizzi, M R; Labia, R.

Antimicrob Agents Chemother ; 40(4): 1027-9, 1996 Apr.

Article in English | MEDLINE | ID: mdl-8849221

ABSTRACT

Crude extracts from 115 extended-spectrum beta-lactamase-producing Klebsiella pneumoniae isolates were analyzed biochemically. The TEM-3 type was encountered 108 times, SHV types were encountered 7 times, and the TEM-26 type was encountered only once. For the last one, the gene was identified; an adenine was detected at position 925, as in blaTEM-26B not in blaTEM-26.

Subject(s)

Klebsiella pneumoniae/metabolism , beta-Lactamases/metabolism , beta-Lactams/metabolism , France , Klebsiella pneumoniae/drug effects , Klebsiella pneumoniae/genetics , beta-Lactam Resistance , beta-Lactamases/genetics , beta-Lactams/pharmacology

ABSTRACT

Subject(s)

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