1.
ChemMedChem
; 6(4): 623-7, 2011 Apr 04.
Article
in English
| MEDLINE
| ID: mdl-21442757
Subject(s)
Neoplasms/drug therapy , Oligopeptides/therapeutic use , Amino Acid Sequence , Animals , Cell Line, Tumor , Genetic Vectors/drug effects , HeLa Cells , Humans , Mice , Molecular Sequence Data , NIH 3T3 Cells , Neoplasms/metabolism , Neoplasms/pathology , Oligopeptides/chemistry , Positron-Emission Tomography/methods , Structure-Activity Relationship
2.
Angew Chem Int Ed Engl
; 48(24): 4344-8, 2009.
Article
in English
| MEDLINE
| ID: mdl-19425037
ABSTRACT
A supramolecular approach has been developed for the preparation of supramolecular nanoparticles (SNPs) with variable sizes (30-450 nm) from three different molecular building blocks using a cyclodextrin/adamantane recognition system. Positron emission tomography (PET) was employed to study the biodistribution and lymph node drainage of the SNPs in mice. The sizes of the SNPs affect their in vivo characteristics (see picture).