Does Proximal Placement of the Syndesmotic Reduction Clamp Affect the Optimal Position for the Medial Tine? A Cadaveric Pilot Study.

Sagittal plane syndesmotic malreduction is associated with off-axis, eccentric reduction clamping and preferential placement of the medial tine anteriorly has been proposed to minimize the malreduction risk. Although clamp placement 1cm proximal to the plafond is recommend, no previous study has assessed whether differences in the anatomic position of the fibula within the incisura (eccentric 1cm superior and concentric 2 cm superior to the tibial plafond) affect the optimal position for the clamps medial tine during reduction of the syndesmosis. The purpose of the present cadaveric pilot study was to evaluate and compare the sagittal syndesmotic malreduction rate with various clamping vectors, 1cm and 2cm from the tibial plafond, respectively. Six through the knee cadaveric specimens were obtained. Kirschner wires and a surgical maker were used to denote placement of the reduction clamp laterally on the peroneal ridge of the fibula, and medially within the anterior, middle, and posterior thirds (Zones A, B, C) of tibia's width; 1 cm and 2 cm from the plafond. CT scans were obtained as controls, followed by destabilization of the syndesmosis. Reductions were then performed sequentially at each level (1 cm, 2 cm) and zone (A, B, C); and CT scans repeated for assessment. In most specimens (n = 5), an eccentric (1 cm) to concentric (2 cm) positional transition was observed within incisura fibularis. The transition altered the resulting fibular displacements in some specimens (2A anterior, vs 2B posterior), resulting in a higher malreduction rate with anterior (zone 2A, 33%) vs central (Zone 2B, 17%) positioning of medial tine. Although no definitive conclusions can be reached from the present pilot study, future studies with a greater number of specimens and clamping vectors are warranted to determine whether positional transitions of the fibula within the incisura fibularis affect the optimal position for the clamps medial tine.

Comparison of Different Magnitudes of Applied Syndesmotic Clamp Force: A Cadaveric Study.

Overcompression of the ankle syndesmosis was once thought to be improbable. Recent studies using computerized tomography (CT) however, have demonstarted otherwise; raising pertinent questions regarding the factors associated with and consequences of syndesmotic overcompression. The purpose of the present study was to directly compare different magnitudes of applied clamp force on the coronal reduction of ankle syndesmosis. Eight through-the-knee cadaveric specimens were obtained. Fiducial cannulated screws were placed in the tibia and fibula to standardize placement of the reduction clamp's tines. CT scans were obtained as baseline controls, followed by destabilization of the syndesmosis. Reductions were then performed using a clamp equipped with an inline load cell, and objective forces (60, 80, 100, 120, 140, and 160 N) applied sequentially to each of the specimens. The syndesmosis was fixed with a single quadricortical screw, and CT were scans repeated. Applied clamp forces of 60 and 80 N resulted in lateral fibular displacement and undercompression (42.9% and 57.1%, respectively), whereas forces of 140 and 160 N resulted in medial fibular displacement (p = .011 and p = .001) and overcompression (100%). The smallest mediolateral displacements were observed with 100 and 120 N, respectively. Malreduction assessment with CT was superior to traditional radiographs [r(54) = 0.22; 95% confidence interval -0.04 to 0.45; p = .101]. In our cadaveric model, an applied clamp force of 100 N most effectively mitigated iatrogenic coronal syndesmotic malreduction from under- or overcompression. Although additional research is warranted, based on the data, inherent variabilities in the applied clamp force by surgeons appear to contribute to the unacceptably high coronal syndesmotic malreduction rate.

Al Valence Controls the Coordination and Stability of Cationic Aluminum-Oxygen Clusters in Reactions of Aln+ with Oxygen.

The reactivity of cationic aluminum clusters with oxygen is studied via a customized time-of-flight mass spectrometer. Unlike the etching effect for anionic aluminum clusters exposed to oxygen, here, the cationic Aln+ clusters react and produce a range of small AlnOm+ clusters. Relatively large-mass abundances are found for Al3O4+, Al4O5+, and Al5O7+ at lower O2 reactivity, while at higher O2 concentration, oxygen addition leads to Al2O7+, Al3O6,8-10+, and Al4O7,9+, showing relatively high abundance, and Al5O7+ remains as a stable species dominating the Al5Om+ distribution. To understand these results, we have investigated the structures and stabilities of the AlnOm+ clusters. First-principles theoretical investigations reveal the structures, highest occupied molecular orbital (HOMO)-lowest unoccupied molecular orbital (LUMO) gaps, fragmentation energies, ionization energies, and Hirshfield charge of the AlnOm+ clusters (2 ≤ n ≤ 7; 0 ≤ m ≤ 10). Energetically, Al3O4+, Al4O5+, and Al5O7+ are calculated to be most stable with high fragmentation energies; however, they still allow for the chemisorption of additional O2 with large binding energies leading to clusters with higher O/Al ratios. The stability of the species is consistent with Al possessing three valence electrons, while O typically accepts two, leading to the expectation that Al3O4+, Al5O7+, and Al7O10+ are reasonably stable. In addition to this, Al3O+, Al5O3+, and Al7O5+ are found to exhibit large HOMO-LUMO gaps associated with the different oxidation states of Al. The oxygen-rich species such as Al2O7+, Al3O10+, and Al4O9+ all display superoxide structures providing further insights into the oxidation of aluminum clusters.

Multiple-Valence Aluminum and the Electronic and Geometric Structure of Al nO m Clusters.

Electronic stability in aluminum clusters is typically associated with either closed electronic shells of delocalized electrons or a +3 oxidation state of aluminum. To investigate whether there are alternative routes toward electronic stability in aluminum oxide clusters, we used theoretical methods to examine the geometric and electronic structure of Al nO m (2 ≤ n ≤ 7; 1 ≤ m ≤ 10) clusters. Electronically stable clusters with large HOMO-LUMO (highest occupied molecular orbital and lowest unoccupied molecular orbital) gaps were identified and could be grouped into two categories. (1) Al2 nO3 n clusters with a +3 oxidation state on the aluminum and (2) planar clusters including Al4O4, Al5O3, Al6O5, and Al6O6. The structures of the planar clusters have external Al atoms bound to a single O atom. Their electronic stability is explained by the multiple-valence Al sites, with the internal Al atoms having an oxidation state of +3, whereas the external Al atoms have an oxidation state of +1.

Synovial sarcoma: a case report.

Synovial sarcoma most commonly affects adults in the third to fifth decades of life, and is the most common sarcoma of the foot. The tumors are encapsulated and frequently in contact with bone. Because there are often few anatomical barriers, malignant spread to surrounding nerves and vasculature is common. This article discusses the case of a young patient who presented to the foot and ankle clinic with soft tissue swelling in the right foot, and the imaging protocol for such a patient. A literature review of synovial sarcoma is also presented.