Influence of rest interval on foot-tibia coordination with chronic ankle instability during the Star Excursion Balance Test.

The purpose of this study was to determine whether different rest intervals affect performance on the Star Excursion Balance Test (SEBT) associated with chronic ankle instability (CAI) and whether foot-tibia coordination can be associated factors that may help discriminate between individuals with and without CAI during the SEBT. Participants included forty-eight individuals with (n = 24) and without CAI (n = 24). Subjects completed 3 trials in each of the 3 reach directions (anteromedial, medial, posteromedial) in random order. A total of three visits were required to complete the 3 rest interval conditions (10, 20, 40 s). Coupling angles (CA) of tibial internal rotation/dorsiflexion (TIR/DF) and tibial internal rotation/eversion (TIR/EV) were calculated and compared between groups in each direction for each rest interval. Individuals with CAI showed greater CAs of TIR/DF in the M direction (p = 0.01) and of TIR/EV in the P direction (p = 0.04) than healthy individuals in 20 s rest interval time. Overall, joint CAs were different between healthy individuals and those with CAI during the SEBT regardless of rest interval. Based on these results, rest interval and a natural result of CAI could alter ankle joint coordination in comparison of healthy individuals when performing the SEBT.

Altered Kinematics and Time to Stabilization During Drop-Jump Landings in Individuals With or Without Functional Ankle Instability.

CONTEXT: It has been proposed that altered dynamic-control strategies during functional activity such as jump landings may partially explain recurrent instability in individuals with functional ankle instability (FAI). OBJECTIVE: To capture jump-landing time to stabilization (TTS) and ankle motion using a multisegment foot model among FAI, coper, and healthy control individuals. DESIGN: Cross-sectional study. SETTING: Laboratory. PATIENTS OR OTHER PARTICIPANTS: Participants were 23 individuals with a history of at least 1 ankle sprain and at least 2 episodes of giving way in the past year (FAI), 23 individuals with a history of a single ankle sprain and no subsequent episodes of instability (copers), and 23 individuals with no history of ankle sprain or instability in their lifetime (controls). Participants were matched for age, height, and weight (age = 23.3 ± 3.8 years, height = 1.71 ± 0.09 m, weight = 69.0 ± 13.7 kg). INTERVENTION(S): Ten single-legged drop jumps were recorded using a 12-camera Vicon MX motion-capture system and a strain-gauge force plate. MAIN OUTCOME MEASURES: Mediolateral (ML) and anteroposterior (AP) TTS in seconds, as well as forefoot and hindfoot sagittal- and frontal-plane angles at jump-landing initial contact and at the point of maximum vertical ground reaction force were calculated. RESULTS: For the forefoot and hindfoot in the sagittal plane, group differences were present at initial contact (forefoot: P = .043, hindfoot: P = .004). At the hindfoot, individuals with FAI displayed more dorsiflexion than the control and coper groups. Time to stabilization differed among groups (AP TTS: P < .001; ML TTS: P = .040). Anteroposterior TTS was longer in the coper group than in the FAI or control groups, and ML TTS was longer in the FAI group than in the control group. CONCLUSIONS: During jump landings, copers showed differences in sagittal-plane control, including less plantar flexion at initial contact and increased AP sway during stabilization, which may contribute to increased dynamic stability.

Wobble Board Rehabilitation for Improving Balance in Ankles With Chronic Instability.

OBJECTIVE: To quantify improvements in clinical impairments using a wobble board rehabilitation protocol for chronic ankle instability (CAI). DESIGN: Prospective randomized controlled trial. SETTING: Laboratory. PATIENTS: Thirty-four participants with "giving way" and history of ankle sprains were randomly assigned to a rehabilitation group (REH) (170.22 ± 8.71 cm; 75.57 ± 13.55 kg; 22.94 ± 2.77 years) or control group (CON) (168.57 ± 9.81 cm; 77.19 ± 19.93 kg; 23.18 ± 3.64 years). INTERVENTIONS: Four weeks with no intervention for CON or wobble board rehabilitation for REH, consisting of 3 sessions per week of 5 repetitions. MAIN OUTCOME MEASURES: Dependent variables were preintervention and postintervention score on foot lift test (average number of errors), Time-in-Balance Test (TBT) (longest time), Star Excursion Balance Test (SEBT)-anteromedial, medial, and posteromedial (average reach distance normalized to leg length), side hop test (fastest time), and figure-of-eight hop test (fastest time). RESULTS: Main effects for time were significant for all measures (P < 0.05); but main effects for groups were not (P > 0.05) except for SEBT-anteromedial reach direction. Significant interactions were found for all dependent measures (P < 0.05) except for TBT (P > 0.05). Post hoc testing of significant interactions showed REH improved performance at posttest, whereas CON did not. CONCLUSIONS: These findings demonstrate that a single intervention using a wobble board improved static and dynamic balance deficits associated with CAI. CLINICAL RELEVANCE: This approach provides a potentially more economical, time efficient, and space efficient means of improving clinical outcome measures associated with CAI in patients who are physically active.

Noise-Enhanced Eversion Force Sense in Ankles With or Without Functional Instability.

CONTEXT: Force sense impairments are associated with functional ankle instability. Stochastic resonance stimulation (SRS) may have implications for correcting these force sense deficits. OBJECTIVE: To determine if SRS improved force sense. DESIGN: Case-control study. SETTING: Research laboratory. PATIENTS OR OTHER PARTICIPANTS: Twelve people with functional ankle instability (age = 23 ± 3 years, height = 174 ± 8 cm, mass = 69 ± 10 kg) and 12 people with stable ankles (age = 22 ± 2 years, height = 170 ± 7 cm, mass = 64 ± 10 kg). INTERVENTION(S): The eversion force sense protocol required participants to reproduce a targeted muscle tension (10% of maximum voluntary isometric contraction). This protocol was assessed under SRSon and SRSoff (control) conditions. During SRSon, random subsensory mechanical noise was applied to the lower leg at a customized optimal intensity for each participant. MAIN OUTCOME MEASURE(S): Constant error, absolute error, and variable error measures quantified accuracy, overall performance, and consistency of force reproduction, respectively. RESULTS: With SRS, we observed main effects for force sense absolute error (SRSoff = 1.01 ± 0.67 N, SRSon = 0.69 ± 0.42 N) and variable error (SRSoff = 1.11 ± 0.64 N, SRSon = 0.78 ± 0.56 N) (P < .05). No other main effects or treatment-by-group interactions were found (P > .05). CONCLUSIONS: Although SRS reduced the overall magnitude (absolute error) and variability (variable error) of force sense errors, it had no effect on the directionality (constant error). Clinically, SRS may enhance muscle tension ability, which could have treatment implications for ankle stability.

Trunk-rotation differences at maximal reach of the star excursion balance test in participants with chronic ankle instability.

CONTEXT: Functional reach on the Star Excursion Balance Test is decreased in participants with chronic ankle instability (CAI). However, comprehensive 3-dimensional kinematics associated with these deficits have not been reported. OBJECTIVE: To determine if lower extremity kinematics differed in CAI participants during anteromedial, medial, and posteromedial reach on the Star Excursion Balance Test. DESIGN: Case-control study. SETTING: Sports medicine research laboratory. PATIENTS OR OTHER PARTICIPANTS: Twenty CAI participants (age = 24.15 ± 3.84 years, height = 168.95 ± 11.57 cm, mass = 68.95 ± 16.29 kg) and 20 uninjured participants (age = 25.65 ± 5.58 years, height = 170.14 ± 8.75 cm, mass = 69.89 ± 10.51 kg) with no history of ankle sprain. We operationally defined CAI as repeated episodes of ankle "giving way" or "rolling over" or both, regardless of neuromuscular deficits or pathologic laxity. All CAI participants scored ≤26 on the Cumberland Ankle Instability Tool. INTERVENTION(S): Star Excursion Balance Test reaches in the anteromedial, medial, and posteromedial directions. The CAI participants used the unstable side as the stance leg. Control participants were sex, height, mass, and side matched to the CAI group. The 3-dimensional kinematics were assessed with a motion-capture system. MAIN OUTCOME MEASURE(S): Group differences on normalized reach distance, trunk, pelvis, and hip-, knee-, and ankle-joint angles at maximum Star Excursion Balance Test reach. RESULTS: No reach-distance differences were detected between CAI and uninjured participants in any of the 3 reach directions. With anteromedial reach, trunk rotation (t(1,38) = 3.06, P = .004), pelvic rotation (t(1,38) = 3.17, P = .003), and hip flexion (t(1,38) = 2.40, P = .002) were greater in CAI participants. With medial reach, trunk flexion (t(1,38) = 6.39, P = .05) was greater than for uninjured participants. No differences were seen with posteromedial reach. CONCLUSIONS: We did not detect reach-distance differences in any direction. However, participants with CAI rotated the trunk and pelvis more toward the stance leg than did stable-ankle participants during anteromedial and medial reach, possibly to help maintain a proximal stable posture and compensate for distal instability. These joint-angle differences with Star Excursion Balance Test performance may represent unique compensatory patterns for those with CAI.

Recalibration and validation of the Cumberland Ankle Instability Tool cutoff score for individuals with chronic ankle instability.

OBJECTIVE: To independently recalibrate and revalidate the Cumberland Ankle Instability Tool (CAIT) cutoff score for discriminating individuals with and without chronic ankle instability (CAI). There are concerns the original cutoff score (≤27) may be suboptimal for use in the CAI population. DESIGN: Case control. SETTING: Research laboratory. PARTICIPANTS: Two independent datasets were used (total N=200). Dataset 1 included 61 individuals with a history of ≥1 ankle sprain and ≥2 episodes of giving way in the last year (CAI group) and 57 participants with no history of ankle sprain or instability in their lifetime (uninjured group). Dataset 2 included 27 uninjured participants, 29 participants with CAI, and 26 individuals with a history of a single ankle sprain and no subsequent instability (copers). INTERVENTIONS: All participants completed the CAIT during a single session. In dataset 1, a receiver operating characteristic (ROC) curve was calculated using the CAIT score and group membership as test variables. The ideal cutoff score was identified using the Youden index. The recalibrated cutoff score was validated in dataset 2 using the ROC analysis and clinimetric characteristics. MAIN OUTCOME MEASURES: CAIT cutoff score and clinimetrics. RESULTS: In dataset 1, the optimal cutoff score was ≤25, which is lower than previously reported. In dataset 2, the recalibrated cutoff score demonstrated a sensitivity of 96.6%, specificity of 86.8%, positive likelihood ratio of 7.318, and negative likelihood ratio of .039. There were 7 false positives and 1 false negative. CONCLUSIONS: The recalibrated CAIT score demonstrated very good clinimetric properties; all properties improved compared with the original cutoff score. Clinicians using the CAIT should use the recalibrated cutoff score to maximize test characteristics. Caution should be taken with copers, who had a high rate of false positives.

Postural-stability tests that identify individuals with chronic ankle instability.

CONTEXT: Chronic ankle instability (CAI) is characterized by repeated ankle sprains, which have been linked to postural instability. Therefore, it is important for clinicians to identify individuals with CAI who can benefit from rehabilitation. OBJECTIVE: To assess the likelihood that CAI participants will exhibit impaired postural stability and that healthy control participants will exhibit better test performance values. DESIGN: Case-control study. SETTING: Laboratory. PATIENTS OR OTHER PARTICIPANTS: People with CAI (n = 17, age = 23 ± 4 years, height = 168 ± 9 cm, weight = 68 ± 12 kg) who reported ankle "giving-way" sensations and healthy volunteers (n = 17, age = 23 ± 3 years, height = 168 ± 8 cm, weight = 66 ± 12 kg). INTERVENTION(S): Participants performed 7 balance tests: Balance Error Scoring System (BESS), time in balance, foot lift, single-legged stance on a force plate, Star Excursion Balance Test, side hop, and figure-of-8 hop. MAIN OUTCOME MEASURE(S): Balance was quantified with errors (score) for the BESS, length of time balancing (seconds) for time-in-balance test, frequency of foot lifts (score) for foot-lift test, velocity (cm/s) for all center-of-pressure velocity measures, excursion (cm) for center-of-pressure excursion measures, area (cm2) for 95% confidence ellipse center-of-pressure area and center-of-pressure rectangular area, time (seconds) for anterior-posterior and medial-lateral time-to-boundary (TTB) measures, distance reached (cm) for Star Excursion Balance Test, and time (seconds) to complete side-hop and figure-of-8 hop tests. We calculated area-under-the-curve values and cutoff scores and used the odds ratio to determine if those with and without CAI could be distinguished using cutoff scores. RESULTS: We found significant area-under-the-curve values for 4 static noninstrumented measures, 3 force-plate measures, and 3 functional measures. Significant cutoff scores were noted for the time-in-balance test (≤25.89 seconds), foot-lift test (≥5), single-legged stance on the firm surface (≥3 errors) and total (≥14 errors) on the BESS, center-of-pressure resultant velocity (≥1.56 cm/s), standard deviations for medial-lateral (≤1.56 seconds) time-to-boundary and anterior-posterior (≤3.78 seconds) time-to-boundary test, posteromedial direction on the Star Excursion Balance Test (≤0.91), side-hop test (≥12.88 seconds), and figure-of-8 hop test (≥17.36 seconds). CONCLUSIONS: Clinicians can use any of the 10 significant measures with their associated cutoff scores to identify those who could benefit from rehabilitation that reestablishes postural stability.

Clinical examination results in individuals with functional ankle instability and ankle-sprain copers.

CONTEXT: Why some individuals with ankle sprains develop functional ankle instability and others do not (ie, copers) is unknown. Current understanding of the clinical profile of copers is limited. OBJECTIVE: To contrast individuals with functional ankle instability (FAI), copers, and uninjured individuals on both self-reported variables and clinical examination findings. DESIGN: Cross-sectional study. SETTING: Sports medicine research laboratory. PATIENTS OR OTHER PARTICIPANTS: Participants consisted of 23 individuals with a history of 1 or more ankle sprains and at least 2 episodes of giving way in the past year (FAI: Cumberland Ankle Instability Tool [CAIT] score = 20.52 ± 2.94, episodes of giving way = 5.8 ± 8.4 per month), 23 individuals with a history of a single ankle sprain and no subsequent episodes of instability (copers: CAIT score = 27.74 ± 1.69), and 23 individuals with no history of ankle sprain and no instability (uninjured: CAIT score = 28.78 ± 1.78). INTERVENTION(S): Self-reported disability was recorded using the CAIT and Foot and Ankle Ability Measure for Activities of Daily Living and for Sports. On clinical examination, ligamentous laxity and tenderness, range of motion (ROM), and pain at end ROM were recorded. MAIN OUTCOME MEASURE(S): Questionnaire scores for the CAIT, Foot and Ankle Ability Measure for Activities of Daily Living and for Sports, ankle inversion and anterior drawer laxity scores, pain with palpation of the lateral ligaments, ankle ROM, and pain at end ROM. RESULTS: Individuals with FAI had greater self-reported disability for all measures (P < .05). On clinical examination, individuals with FAI were more likely to have greater talar tilt laxity, pain with inversion, and limited sagittal-plane ROM than copers (P < .05). CONCLUSIONS: Differences in both self-reported disability and clinical examination variables distinguished individuals with FAI from copers at least 1 year after injury. Whether the deficits could be detected immediately postinjury to prospectively identify potential copers is unknown.

Customized noise-stimulation intensity for bipedal stability and unipedal balance deficits associated with functional ankle instability.

CONTEXT: Stochastic resonance stimulation (SRS) administered at an optimal intensity could maximize the effects of treatment on balance. OBJECTIVE: To determine if a customized optimal SRS intensity is better than a traditional SRS protocol (applying the same percentage sensory threshold intensity for all participants) for improving double- and single-legged balance in participants with or without functional ankle instability (FAI). DESIGN: Case-control study with an embedded crossover design. SETTING: Laboratory. PATIENTS OR OTHER PARTICIPANTS: Twelve healthy participants (6 men, 6 women; age = 22 ± 2 years, height = 170 ± 7 cm, mass = 64 ± 10 kg) and 12 participants (6 men, 6 women; age = 23 ± 3 years, height = 174 ± 8 cm, mass = 69 ± 10 kg) with FAI. INTERVENTION(S): The SRS optimal intensity level was determined by finding the intensity from 4 experimental intensities at the percentage sensory threshold (25% [SRS25], 50% [SRS50], 75% [SRS75], 90% [SRS90]) that produced the greatest improvement in resultant center-of-pressure velocity (R-COPV) over a control condition (SRS0) during double-legged balance. We examined double- and single-legged balance tests, comparing optimal SRS (SRS(opt1)) and SRS0 using a battery of center-of-pressure measures in the frontal and sagittal planes. MAIN OUTCOME MEASURE(S): Anterior-posterior (A-P) and medial-lateral (M-L) center-of-pressure velocity (COPV) and center-of-pressure excursion (COPE), R-COPV, and 95th percentile center-of-pressure area ellipse (COPA-95). RESULTS: Data were organized into bins that represented optimal (SRS(opt1)), second (SRS(opt2)), third (SRS(opt3)), and fourth (SRS(opt4)) improvement over SRS0. The SRS(opt1) enhanced R-COPV (P ≤ .05) over SRS0 and other SRS conditions (SRS0 = 0.94 ± 0.32 cm/s, SRS(opt1) = 0.80 ± 0.19 cm/s, SRS(opt2) = 0.88 ± 0.24 cm/s, SRS(opt3) = 0.94 ± 0.25 cm/s, SRS(opt4) = 1.00 ± 0.28 cm/s). However, SRS did not improve R-COPV over SRS0 when data were categorized by sensory threshold. Furthermore, SRS(opt1) improved double-legged balance over SRS0 from 11% to 25% in all participants for the center-of-pressure frontal- and sagittal-plane assessments (P ≤ .05). The SRS(opt1) also improved single-legged balance over SRS0 from 10% to 17% in participants with FAI for the center-of-pressure frontal- and sagittal-plane assessments (P ≤ .05). The SRS(opt1) did not improve single-legged balance in participants with stable ankles. CONCLUSIONS: The SRS(opt1) improved double-legged balance and transfers to enhancing single-legged balance deficits associated with FAI.

Scapular kinematics and subacromial-impingement syndrome: a meta-analysis.

CONTEXT: The literature does not present a consistent pattern of altered scapular kinematics in patients with shoulder-impingement syndrome (SIS). OBJECTIVES: To perform meta-analyses of published comparative studies to determine the consistent differences in scapular kinematics between subjects with SIS and controls. In addition, the purpose was to analyze factors of the data-collection methods to explain the inconsistencies in reported kinematics. The results of this study will help guide future research and enable our understanding of the relationship between scapular kinematics and SIS. EVIDENCE ACQUISITION: A search identified 65 studies; 9 papers met inclusion criteria. Sample sizes, means, and SDs of 5 scapular-kinematic variables were extracted or obtained from each paper's lead author. Standard difference in the mean between SIS and controls was calculated. Moderator variables were plane of arm elevation, level of arm elevation (ARM) and population (POP). EVIDENCE SYNTHESIS: Overall, the SIS group had less scapular upward rotation (UR) and external rotation (ER) and greater clavicular elevation (ELE) and retraction (RET) but no differences in scapular posterior tilt (PT). In the frontal plane, SIS subjects showed greater PT and ER, and in the scapular plane, less UR and ER and greater ELE and RET. There was also greater ELE and RET in the sagittal plane. There was less UR at the low ARM and greater ELE and RET at the high ARM with SIS. Athletes and overhead workers showed less UR, while athletes showed greater PT and workers showed less PT and ER. The general population with SIS had greater ELE and RET only. CONCLUSIONS: Subjects with SIS demonstrated altered scapular kinematics, and these differences are influenced by the plane, ARM, and POP. Athletes and overhead workers have a different pattern of scapular kinematics than the general population. The scapular plane is most likely to demonstrate altered kinematics. These factors should be considered when designing futures studies to assess the impact of altered kinematics in patients with SIS.

Fatigue's effect on eversion force sense in individuals with and without functional ankle instability.

CONTEXT: Force sense (FS), the proprioceptive ability to detect muscle-force generation, has been shown to be impaired in individuals with functional ankle instability (FAI). Fatigue can also impair FS in healthy individuals, but it is unknown how fatigue affects FS in individuals with FAI. OBJECTIVE: To assess the effect of fatigue on ankle-eversion force-sense error in individuals with and without FAI. DESIGN: Case control with repeated measures. SETTING: Sports medicine research laboratory. PARTICIPANTS: 32 individuals with FAI and 32 individuals with no ankle sprains or instability in their lifetime. FAI subjects had a history of ≥1 lateral ankle sprain and giving-way ≥1 episode per month. INTERVENTIONS: Three eversion FS trials were captured per load (10% and 30% of maximal voluntary isometric contraction) using a load cell before and after a concentric eversion fatigue protocol. MAIN OUTCOME MEASURES: Trial error was the difference between the target and reproduction forces. Constant error (CE), absolute error (AE), and variable error (VE) were calculated from 3 trial errors. A Group × Fatigue × Load repeated-measures ANOVA was performed for each error. RESULTS: There were no significant 3-way interactions or 2-way interactions involving group (all P > .05). CE and AE had a significant 2-way interaction between load and fatigue (CE: F1,62 = 8.704, P = .004; AE: F1,62 = 4.024, P = .049), and VE had a significant main effect for fatigue (F1,62 = 5.130, P = .027), all of which indicated increased FS error with fatigue at 10% load. However, at 30% load only VE increased with fatigue. The FAI group had greater error as measured by AE (F1,62 = 4.571, P = .036) but not CE or VE (P > .05). CONCLUSIONS: Greater AE indicates that FAI individuals are less accurate in their force production. Fatigue impaired force sense in all subjects equally. These deficits provide evidence of impaired proprioception with fatigue and in individuals with FAI.

Balance assessments for predicting functional ankle instability and stable ankles.

A number of instrumented and non-instrumented measures are used to detect balance deficits associated with functional ankle instability (FAI). Determining outcome measures that detect balance deficits associated with FAI might assist clinicians in identifying impairments that may otherwise go undetected with less responsive balance measures. Thus, our objective was to determine the balance measure that best predicted ankle group membership (FAI or stable ankle). Participants included 17 subjects without a history of ankle sprains (168±9 cm, 66±14 kg, 24±5 yr) and 17 subjects with FAI (172±9 cm, 71±11 kg, 22±3 yr). Balance trials were performed without vision and subjects stood on a single leg as motionless as possible for 20s. Balance was quantified with center-of-pressure measures (velocity, area) and error score. Measures were positively correlated with each other (r range: 0.60-0.76). The multifactorial model with all three measures best predicted group membership (F((3,30))=7.20, P=0.001; R(2)=0.42; percent classified correctly=77%), and was followed by the multifactorial model with resultant center-of-pressure velocity and error score (F((2,31))=8.73, P=0.001; R(2)=0.36; percent classified correctly=74%). The resultant center-of-pressure velocity (F((1,32))=13.46, P=0.001; R(2)=0.30; percent classified correctly=74%; unique variance=12.7%) and error score (F((1,32))=12.51, P=0.001; R(2)=0.28; percent classified correctly=71%; unique variance=12.0%) predicted group membership; however, 95th percentile center-of-pressure area ellipse did not (F((1,32))=4.16, P=0.05; R(2)=0.12; percent classified correctly=65%; unique variance=5.8%). A multifactorial single leg balance assessment is best for predicting group membership. COPV is the best single predictor of group membership, but clinicians may use error score to identify deficits associated with FAI if force plates are not available.

Functional ankle instability and health-related quality of life.

CONTEXT: To our knowledge, no authors have assessed health-related quality of life (HR-QOL) in participants with functional ankle instability (FAI). Furthermore, the relationships between measures of ankle functional limitation and HR-QOL are unknown. OBJECTIVE: To use the Short Form-36v2 Health Survey (SF-36) to compare HR-QOL in participants with or without FAI and to determine whether HR-QOL was related to functional limitation. DESIGN: Cross-sectional study. SETTING: Sports medicine research laboratory. PATIENTS OR OTHER PARTICIPANTS: Sixty-eight participants with FAI (defined as at least 1 lateral ankle sprain and 1 episode of giveway per month) or without FAI were recruited (FAI group: n = 34, age = 25 ± 5 years, height = 1.71 ± 0.08 m, mass = 74.39 ± 12.78 kg, Cumberland Ankle Instability Tool score = 19.3 ± 4; uninjured [UI] group: n = 34, age = 23 ± 4 years, height = 1.69 ± 0.08 m, mass = 67.94 ± 11.27 kg, Cumberland Ankle Instability Tool score = 29.4 ± 1). MAIN OUTCOME MEASURE(S): All participants completed the SF-36 as a measure of HR-QOL and the Foot and Ankle Ability Measure (FAAM) and the FAAM Sport version (FAAMS) as assessments of functional limitation. To compare the FAI and UI groups, we calculated multiple analyses of variance followed by univariate tests. Additionally, we correlated the SF-36 summary component scale and domain scales with the FAAM and FAAMS scores. RESULTS: Participants with FAI had lower scores on the SF-36 physical component summary (FAI = 54.4 ± 5.1, UI = 57.8 ± 3.7, P = .005), physical function domain scale (FAI = 54.5 ± 3.8, UI = 56.6 ± 1.2, P = .004), and bodily pain domain scale (FAI = 52.0 ± 6.7, UI = 58.5 ± 5.3, P < .005). Similarly, participants with FAI had lower scores on the FAAM (FAI = 93.7 ± 8.4, UI = 99.5 ± 1.4, P < .005) and FAAMS (FAI = 84.5 ± 8.4, UI = 99.8 ± 0.72, P < .005) than did the UI group. The FAAM score was correlated with the physical component summary scale (r = 0.42, P = .001) and the physical function domain scale (r = 0.61, P < .005). The FAAMS score was correlated with the physical function domain scale (r = 0.47, P < .005) and the vitality domain scale (r = 0.36, P = .002). CONCLUSIONS: Compared with UI participants, those with FAI had less HR-QOL and more functional limitations. Furthermore, positive correlations were found between HR-QOL and functional limitation measures. This suggests that ankle impairment may reduce overall HR-QOL.

Repeatability of the modified Oxford foot model during gait in healthy adults.

BACKGROUND: The Oxford foot model (OFM) is a multi-segment model for calculating hindfoot and forefoot motion. Limited information is available regarding the repeatability and error of this model in adults. Therefore the purpose of this study was to assess the intra-tester reliability of OFM hindfoot and forefoot gait kinematics in adults at initial contact (IC) and toe-off (TO). METHODS: Seventeen healthy adults (age=25.1±4.8 years, height=1.75±0.10m, weight=74.0±12.4kg) were tested on a single visit, during which 1 examiner recorded 2 sessions. For each session, 10 walking trials were recorded using a 12-camera motion analysis system (Vicon, Oxford, UK). Markers were removed and re-applied between sessions. Dynamic hindfoot and forefoot angles were calculated both with and without referencing to neutral stance (assuming neutral stance angles are zero in all planes). Using the 10 trial average, intraclass correlation coefficients (ICC(2,k)) and standard errors of the measurement were calculated for each reference condition, anatomical plane, and joint (hindfoot, forefoot). RESULTS: Referencing to neutral stance resulted in good reliability (ICC≥0.83) and small error (≤2.45°) for hindfoot and forefoot angle in all planes. Without referencing to neutral stance, sagittal and transverse plane reliability were also good (ICC≥0.90) and error small (≤3.14°); however, frontal plane reliability was poor (ICC≤0.77), with large error (≥4.86°). DISCUSSION: Our results show that overall the OFM is reliable during adult gait. Reliability for adults is higher than previously reported in children. Referencing joint angles to neutral stance decreased error by up to 2° from previous reports.

Concentric evertor strength differences and functional ankle instability: a meta-analysis.

OBJECTIVE: To determine whether concentric evertor muscle weakness was associated with functional ankle instability (FAI). DATA SOURCES: We conducted an electronic search through November 2007, limited to English, and using PubMed, Pre-CINAHL, CINAHL, and SPORTDiscus. A forward search was conducted using the Science Citation Index on studies from the electronic search. Finally, we conducted a hand search of all selected studies and contacted the respective authors to identify additional studies. We included peer-reviewed manuscripts, dissertations, and theses. STUDY SELECTION: We evaluated the titles and abstracts of studies identified by the electronic searches. Studies were selected by consensus and reviewed only if they included participants with FAI or chronic ankle instability and strength outcomes. Studies were included in the analysis if means and SDs (or other relevant statistical information, such as P values or t values and group n's) were reported for FAI and stable groups (or ankles). DATA EXTRACTION: Data were extracted by the authors independently, cross-checked for accuracy, and limited to outcomes of concentric eversion strength. We rated each study for quality. Outcomes were coded as either fast or slow velocity (ie, equal to or greater than 110 degrees /s or less than 110 degrees /s, respectively). DATA SYNTHESIS: Data included the means, SDs, and group sample sizes (or other appropriate statistical information) for the FAI and uninjured groups (or ankles). The standard difference in the means (SDM) for each outcome was calculated using the pooled SD. We tested individual and overall SDMs using the Z statistic and comparisons between fast and slow velocities using the Q statistic. Our analysis revealed that ankles with FAI were weaker than stable ankles (SDM = 0.224, Z = 4.0, P < .001, 95% confidence interval = 0.115, 0.333). We found no difference between the fast- and slow-velocity SDMs (SDM(Fast) = 0.189, SDM(Slow) = 0.244, Q = 29.9, df = 24, P = .187). Because of the small SDM, this method of measuring ankle strength in the clinical setting may need to be reevaluated.

Ankle instability is associated with balance impairments: a meta-analysis.

PURPOSE: Our primary purpose was to determine whether balance impairments were associated with functional ankle instability (FAI). METHODS: Our literature search consisted of four parts: 1) an electronic search of PubMed, CINAHL, pre-CINAHL, and SPORTDiscus; 2) a forward search of articles selected from the electronic search using the Science Citation Index; 3) a hand search of the previously selected articles; and 4) a direct contact with corresponding authors of the previously selected articles. We initially identified 145 articles and narrowed these to 23 for inclusion in the meta-analysis. Identified outcomes were categorized by measurement units and balance task type (i.e., dynamic or static). Each study was coded based on whether inclusion or exclusion criteria were identified. Our statistical analysis included fixed, random, or mixed effect analyses based on the presence of within study heterogeneity and whether categories were being compared. RESULTS: FAI was associated with poorer balance (standard difference of the mean [SDM] = 0.455, 95% confidence interval = 0.334-0.577, Z = 7.34, P < 0.001), but no difference existed between dynamic and static measure categories (Q = 3.44, P = 0.063). However, there was a significant difference between the dynamic measures (Q = 6.22, P = 0.013) with both time to stabilization and the Star Excursion Balance Test producing significant SDM and between static measures (Q = 13.00, P = 0.012) with the linear, time, velocity, and other measurement categories (but not area) producing significant SDM. Examination of individual outcomes revealed that time in balance and foot lifts produced very large SDM (3.3 and 4.8, respectively). CONCLUSION: FAI is associated with impaired balance. Due to the relatively large effect sizes and simplicity of use of time in balance and foot lifts, we recommend that further research should establish their clinical validity and clinical cutoff scores.

Force sense deficits in functionally unstable ankles.

The purpose of this study was to determine whether participants with functional ankle instability have deficits in force sense reproduction compared to uninjured participants. Twenty participants with no history of injury and 20 with functional ankle instability volunteered for this investigation. Participants in the instability group had a history of at least one ankle sprain and frequent episodes of giving way. Ankle force sense testing was performed at 10, 20, and 30% of eversion maximal voluntary isometric contraction. Ten trials were performed at each force. Absolute and variable errors were then calculated. We observed significant (p < 0.05) main effects for group for absolute and variable errors. Force sense absolute error was significantly greater in the functionally unstable ankles (3.7 +/- 2.2 N) compared to uninjured ankles (2.8 +/- 1.1 N). Variable error was also significantly greater in the functionally unstable ankles (3.2 +/- 1.8 N) than the uninjured ankles (2.4 +/- 0.8 N). Functional ankle instability is associated with deficits in an individual's ability to accurately reproduce a given force. This deficit may impair an individual's ability to set appropriate muscle force levels to provide stability to the joint.

Enhanced balance associated with coordination training with stochastic resonance stimulation in subjects with functional ankle instability: an experimental trial.

BACKGROUND: Ankle sprains are common injuries that often lead to functional ankle instability (FAI), which is a pathology defined by sensations of instability at the ankle and recurrent ankle sprain injury. Poor postural stability has been associated with FAI, and sports medicine clinicians rehabilitate balance deficits to prevent ankle sprains. Subsensory electrical noise known as stochastic resonance (SR) stimulation has been used in conjunction with coordination training to improve dynamic postural instabilities associated with FAI. However, unlike static postural deficits, dynamic impairments have not been indicative of ankle sprain injury. Therefore, the purpose of this study was to examine the effects of coordination training with or without SR stimulation on static postural stability. Improving postural instabilities associated with FAI has implications for increasing ankle joint stability and decreasing recurrent ankle sprains. METHODS: This study was conducted in a research laboratory. Thirty subjects with FAI were randomly assigned to either a: 1) conventional coordination training group (CCT); 2) SR stimulation coordination training group (SCT); or 3) control group. Training groups performed coordination exercises for six weeks. The SCT group received SR stimulation during training, while the CCT group only performed coordination training. Single leg postural stability was measured after the completion of balance training. Static postural stability was quantified on a force plate using anterior/posterior (A/P) and medial/lateral (M/L) center-of-pressure velocity (COPvel), M/L COP standard deviation (COPsd), M/L COP maximum excursion (COPmax), and COP area (COParea). RESULTS: Treatment effects comparing posttest to pretest COP measures were highest for the SCT group. At posttest, the SCT group had reduced A/P COPvel (2.3 +/- 0.4 cm/s vs. 2.7 +/- 0.6 cm/s), M/L COPvel (2.6 +/- 0.5 cm/s vs. 2.9 +/- 0.5 cm/s), M/L COPsd (0.63 +/- 0.12 cm vs. 0.73 +/- 0.11 cm), M/L COPmax (1.76 +/- 0.25 cm vs. 1.98 +/- 0.25 cm), and COParea (0.13 +/- 0.03 cm2 vs. 0.16 +/- 0.04 cm2) than the pooled means of the CCT and control groups (P < 0.05). CONCLUSION: Reduced values in COP measures indicated postural stability improvements. Thus, six weeks of coordination training with SR stimulation enhanced postural stability. Future research should examine the use of SR stimulation for decreasing recurrent ankle sprain injury in physically active individuals with FAI.

Low-load eversion force sense, self-reported ankle instability, and frequency of giving way.

CONTEXT: Functional ankle instability has been attributed to proprioceptive loss. However, in previous studies of proprioception,authors have not investigated the ability to sense force at the ankle. Additionally, previous investigators have viewed functional ankle instability as either a present or absent condition,rather than a continuum. OBJECTIVE: To determine the relationship of ankle giving-way frequency and perceived ankle instability to ankle eversion force sense. DESIGN: Cohort design. SETTING: Sports medicine research laboratory. PATIENTS OR OTHER PARTICIPANTS: Twenty individuals (5 men,15 women) with a history of unilateral ankle instability. INTERVENTION(S): We tested subjects with 2 loads: 10% and 30% of maximal voluntary isometric contraction. MAIN OUTCOME MEASURE(S): We measured eversion force sense by calculating absolute, constant, and variable errors from a 3-trial force-matching procedure. Furthermore, subjects reported their frequency of giving way in units of times per day,week, or month, and these data were extrapolated to estimate annual giving-way frequency. Finally, subjects answers to 6 questions about ankle stability during typical daily or sports activities were summed to create a perceived ankle instability index. RESULTS: Significant relationships were found for only the 10% maximal voluntary isometric contraction. For absolute error,a positive relationship existed between the number of self reported episodes of giving way and eversion force sense for both ipsilateral (r .58) and contralateral (r .49) testing of the injured ankle. Constant error was correlated with giving way(r = -.56) for ipsilateral testing of the injured ankle. The ankle instability index was also positively correlated with eversion force sense absolute error (r .51) for ipsilateral testing only. CONCLUSIONS: Our results suggest that subjects with ankle instability had difficulty replicating eversion forces. Specifically,larger errors were related to both self-reported giving-way episodes and perceived ankle instability.

Fatigue, vertical leg stiffness, and stiffness control strategies in males and females.

CONTEXT: Fatigue appears to influence musculoskeletal injury rates during athletic activities, but whether males and females respond differently to fatigue is unknown. OBJECTIVE: To determine the influence of fatigue on vertical leg stiffness (K (VERT)) and muscle activation and joint movement strategies and whether healthy males and females respond similarly to fatigue. DESIGN: Repeated-measures design with all data collected during a single laboratory session. SETTING: Laboratory. PATIENTS OR OTHER PARTICIPANTS: Physically active males (n = 11) and females (n = 10). INTERVENTION(S): Subjects performed hopping protocols at 2 frequencies before and after fatigue, which was induced by repeated squatting at submaximal loads. MAIN OUTCOME MEASURE(S): We measured K (VERT) with a forceplate and peak muscle activity of the quadriceps, hamstrings, gastrocnemius, soleus, and anterior tibialis muscles with surface electromyography. Sagittal-plane kinematics at the knee and ankle were recorded with an electrogoniometer. RESULTS: After fatigue, K (VERT) was unchanged for all subjects. However, both males and females demonstrated reduced peak hamstrings ( P = .002) and anterior tibialis ( P = .001) activation, coupled with increased gastrocnemius ( P = .005) and soleus ( P = .001) peak activity, as well as increased quadriceps-hamstrings ( P = .005) and gastrocnemius/soleus-anterior tibialis coactivation ratios ( P = .03) after fatigue. Overall, females demonstrated greater quadriceps-hamstrings coactivation ratios than males, regardless of the fatigue condition ( P = .026). Only females showed increased knee flexion at initial contact after fatigue during hopping ( P = .03). CONCLUSIONS: Although K (VERT) was unaffected, the peak muscle activation and joint movement strategies used to modulate K (VERT) were affected after fatigue. Once fatigued, both males and females used an ankle-dominant strategy, with greater reliance on the ankle musculature and less on the knee musculature. Also, once fatigued, all subjects used an antagonist inhibition strategy by minimizing antagonist coactivation. Overall, females used a more quadriceps-dominant strategy than males, showing greater quadriceps activity and a larger quadriceps-hamstrings coactivation ratio. Changes in muscle activation and coactivation ratios because of fatigue and sex are suggested to alter knee joint stability and increase anterior cruciate ligament injury risk.