1.
Science
; 342(6159): 696-8, 2013 Nov 08.
Article
in English
| MEDLINE
| ID: mdl-24202163
Subject(s)
Climate Change , Disaster Planning , Floods , Research/organization & administration , United States
2.
Sens Actuators B Chem
; 72(2): 134-40, 2001 Jan 25.
Article
in English
| MEDLINE
| ID: mdl-12192685
ABSTRACT
We report an integrated CMOS microluminometer for the detection of low-level bioluminescence in whole cell biosensing applications. This microluminometer is the microelectronic portion of the bioluminescent bioreporter integrated circuit (BBIC). This device uses the n-well/p-substrate junction of a standard bulk CMOS IC process to form the integrated photodetector. This photodetector uses a distributed electrode configuration that minimizes detector noise. Signal processing is accomplished with a current-to-frequency converter circuit that forms the causal portion of the matched filter for dc luminescence in wide-band white noise. Measurements show that luminescence can be detected from as few as 4 x 10(5) cells/ml.