The structure and function of marco, a macrophage class a scavenger receptor.

The class A scavenger receptors are important in many aspects of macrophage biology. The receptor MARCO is a relatively recently described member of this class. The biological role of MARCO is under active investigation, and shows interesting similarities and contrasts to that of the class prototype, SR-A-I/II. This review surveys current knowledge and unanswered questions regarding the structure and function of the MARCO receptor.