ABSTRACT
This retrospective observational study aimed to assess the effect of temperature-humidity index (THI) at calving and in the last trimester of pregnancy and calve-related factors affecting passive transfer of maternal immunoglobulin using Brix refractometry in Holstein calves. Blood samples from 4411 Holstein calves from a single large dairy farm in spring 2022 were used. A subset of data containing 6318 calvings was used to determine the effect of climatic conditions on the occurrence of agammaglobulinemia. Risk factors predictive of failure of passive transfer (FPT) were calculated using multiple logistic models. Females were 1.4 times more likely not to have FPT (56%; Brix% > 8 equivalent to ≥ 10 g/L IgG) than males (47.2%). Calves born as singles increased the likelihood of not presenting FPT (52.6%) than calves born as twins (42.9%). Calves from cows with no dystocic delivery had a lower risk for FPT (odds ratio = 2.3) than calves from cows with dystocia. Agammaglobulinemia was 1.5 and 1.8 times more likely to occur in calves with THI ≥ 80 and ≥ 82 in the last trimester of gestation and at calving, respectively, than in calves not experiencing heat stress. Agammaglobulinemia was twice as likely to occur in male than in female calves. Calves with birth weight ≥ 37 kg and gestation length ≥ 275 kg were less likely to present agammaglobulinemia than lighter calves and calves with shorter gestation periods. This study raises questions for management practices in Holstein calves undergoing in utero heat stress and around calving to avoid agammaglobulinemia.
Subject(s)
Agammaglobulinemia , Cattle Diseases , Dystocia , Animals , Cattle , Female , Male , Pregnancy , Agammaglobulinemia/veterinary , Antibodies , Birth Weight , Dystocia/veterinary , Risk Factors , Retrospective StudiesABSTRACT
BACKGROUND: Surgical site infections (SSIs) are the leading cause of healthcare-associated infections in acute care hospitals in Europe. However, the risk factors for the development of early-onset (EO) and late-onset (LO) SSI have not been elucidated. AIM: This study investigated the predictive factors for EO-SSI and LO-SSI in a large cohort of patients undergoing colorectal surgery. METHODS: We prospectively followed-up adult patients undergoing elective colorectal surgery in 10 hospitals (2011-2014). Patients were divided into three groups: EO-SSI, LO-SSI, or no infection (no-SSI). The cut-off defining EO-SSI and LO-SSI was seven days (median time to SSI development). Different predictive factors for EO-SSI and LO-SSI were analysed, comparing each group with the no-SSI patients. FINDINGS: Of 3701 patients, 320 (8.6%) and 349 (9.4%) developed EO-SSI and LO-SSI, respectively. The rest had no-SSI. Patients with EO-SSI were mostly males, had colon surgery and developed organ-space SSI whereas LO-SSI patients frequently received chemotherapy or radiotherapy and had incisional SSI. Male sex (odds ratio (OR): 1.92; P < 0.001), American Society of Anesthesiologists' physical status >2 (OR: 1.51; P = 0.01), administration of mechanical bowel preparation (OR: 0.7; P = 0.03) and stoma creation (OR: 1.95; P < 0.001) predicted EO-SSI whereas rectal surgery (OR: 1.43; P = 0.03), prolonged surgery (OR: 1.4; P = 0.03) and previous chemotherapy (OR: 1.8; P = 0.03) predicted LO-SSI. CONCLUSION: We found distinctive predictive factors for the development of SSI before and after seven days following elective colorectal surgery. These factors could help establish specific preventive measures in each group.
Subject(s)
Colorectal Surgery/adverse effects , Decision Support Techniques , Surgical Wound Infection/diagnosis , Surgical Wound Infection/epidemiology , Aged , Aged, 80 and over , Europe/epidemiology , Female , Humans , Male , Prospective Studies , Risk FactorsABSTRACT
No disponible
Subject(s)
Humans , Male , Adult , Foodborne Diseases/complications , Foodborne Diseases/diagnosis , Foodborne Diseases/etiology , Histamine/toxicity , Chlorpheniramine/therapeutic use , Adrenal Cortex Hormones/therapeutic use , Fish Products/adverse effects , Fish Products/toxicityABSTRACT
No disponible
Subject(s)
Humans , Male , Female , Upper Extremity Deep Vein Thrombosis/diagnosis , Upper Extremity Deep Vein Thrombosis/therapy , Concurrent Symptoms , Vitamin K/therapeutic use , Upper Extremity Deep Vein Thrombosis/epidemiology , Upper Extremity Deep Vein Thrombosis/prevention & control , Upper Extremity Deep Vein Thrombosis/physiopathology , Paresthesia/complications , Pain/complicationsABSTRACT
No disponible
Subject(s)
Humans , Male , Adult , Hepatitis/complications , Hepatitis/diagnosis , Hepatitis/drug therapy , Coxiella burnetii , Coxiella burnetii/isolation & purification , Seroconversion , Seroconversion/physiology , Doxycycline/therapeutic use , Primary Health Care/standards , Splenomegaly/complications , Infection Control/methods , Infection Control/trendsSubject(s)
Foodborne Diseases/diagnosis , Marine Toxins/poisoning , Seafood/poisoning , Tuna , Animals , Humans , Male , Young AdultABSTRACT
No disponible
