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1.
Rev Bras Epidemiol ; 15(2): 308-14, 2012 Jun.
Article in English | MEDLINE | ID: mdl-22782096

ABSTRACT

Fatal injuries in children caused by motor vehicle accidents represent a common situation in many countries worldwide. The present study addresses the mortality rate in children as vehicle passengers in Brazil, from 1997 to 2005. To evaluate mortality rates, the number of deaths was collected from the National Mortality Information System (SIM) and the population size was obtained using the Brazilian Bureau Census (IBGE) data available at DATASUS. Mortality rates were estimated in three-year periods and analyzed according to age groups (younger than 1 year old, 1-4 years old, 5-9 years old) and geographical regions using a 95% confidence interval. Overall results showed mortality rates of 5.68, 7.32 and 6.78 (per 1,000,000) for the 1997-1999, 2000-2002 and 2003-2005 periods, respectively for the whole country. Children younger than 1 year old had a mortality rate of 10.18 (per 1,000,000), which was higher than for the other age groups. For the period analyzed, the highest rates were observed for the Mid-West and South regions of Brazil, with rates of 13.88 and 11.47 (per 1,000,000), respectively. These results show the risk of fatal injury in children caused by motor vehicle accidents and may contribute to the establishment of educational campaigns aiming injury prevention in children as vehicle passengers.


Subject(s)
Accidents, Traffic/mortality , Brazil/epidemiology , Child , Child, Preschool , Humans , Infant , Time Factors
2.
Rev. bras. epidemiol ; 15(2): 308-314, jun. 2012. tab
Article in English | LILACS | ID: lil-640957

ABSTRACT

Fatal injuries in children caused by motor vehicle accidents represent a common situation in many countries worldwide. The present study addresses the mortality rate in children as vehicle passengers in Brazil, from 1997 to 2005. To evaluate mortality rates, the number of deaths was collected from the National Mortality Information System (SIM) and the population size was obtained using the Brazilian Bureau Census (IBGE) data available at DATASUS. Mortality rates were estimated in three-year periods and analyzed according to age groups (younger than 1 year old, 1-4 years old, 5-9 years old) and geographical regions using a 95% confidence interval. Overall results showed mortality rates of 5.68, 7.32 and 6.78 (per 1,000,000) for the 1997-1999, 2000-2002 and 2003-2005 periods, respectively for the whole country. Children younger than 1 year old had a mortality rate of 10.18 (per 1,000,000), which was higher than for the other age groups. For the period analyzed, the highest rates were observed for the Mid-West and South regions of Brazil, with rates of 13.88 and 11.47 (per 1,000,000), respectively. These results show the risk of fatal injury in children caused by motor vehicle accidents and may contribute to the establishment of educational campaigns aiming injury prevention in children as vehicle passengers.


Lesões fatais em crianças causadas por acidentes de trânsito representam um problema em muitos países. Este estudo analisou a taxa de mortalidade em crianças passageiras de automóveis menores de 10 anos de idade no Brasil, entre 1997 e 2005. Para isso, o número de mortes foi obtido diretamente no banco de dados do Sistema de Informação sobre Mortalidade (SIM) e os dados da população são projeções intercensitárias a partir censo demográfico do Instituto Brasileiro de Geografia e Estatística (IBGE) disponíveis pelo site do DATASUS. Foram calculadas, para os triênios compreendidos no período em estudo, as taxas de mortalidade por acidente de trânsito entre crianças passageiras de automóveis segundo faixa etária (menor que 1 ano, 1 a 4 e 5 a 9) e região geográfica. Os resultados mostraram taxas de mortalidade de 5,68, 7,32 e 6,78 (por 1.000.000), respectivamente, para os períodos 1997-1999, 2000-2002 e 2003-2005 para todo o Brasil. Crianças menores de 1 ano de idade apresentam taxa de mortalidade de 10,18 (por 1,000,000), maior que as observadas para as outras faixas etárias. Para o período 1997-2005, as maiores taxas foram observadas nas regiões Centro-Oeste e Sul, representando, respectivamente, 13,88 e 11,47 (por 1.000.000). Tais resultados mostram a situação de risco da criança em relação a acidentes de trânsito como passageiras de automóveis e contribuem para a elaboração de campanhas educativas de prevenção de lesões.


Subject(s)
Child , Child, Preschool , Humans , Infant , Accidents, Traffic/mortality , Brazil/epidemiology , Time Factors
3.
ASAIO J ; 57(5): 462-5, 2011.
Article in English | MEDLINE | ID: mdl-21841468

ABSTRACT

An implantable centrifugal blood pump has been developed with original features for a ventricle assist device (VAD). This pump is part of a multicenter and international study with objective to offer simple, affordable, and reliable devices to developing countries. Previous computational fluid dynamics investigations were performed followed by prototyping and in vitro tests. Also, previous blood tests for assessment of hemolysis showed mean normalized index of hemolysis (NIH) results of 0.0054 ± 2.46 × 10⁻³ mg/100 L (at 5 L/min and 100 mm Hg). To precede in vivo evaluation, measurements of magnetic coupling interference and enhancements of actuator control were necessary. Methodology was based on the study of two different work situations (1 and 2) studied with two different types of motors (A and B). Situation 1 is when the rotor of pump is closest to the motor and situation 2 its opposite. Torque and mechanical power were collected with a dynamometer (80 g/cm) and then plotted and compared for two situations and both motors. The results showed that motor A has better mechanical behavior and less influence of coupling. Results for situation 1 showed that it is more often under magnetic coupling influence than situation 2. The studies lead to the conclusion that motor A is the best option for in vivo studies as it has less influence of magnetic coupling in both situations.


Subject(s)
Heart-Assist Devices , Biomedical Engineering/methods , Centrifugation , Equipment Design , Hemolysis , Humans , Magnetics , Torque
4.
Artif Organs ; 35(5): 437-42, 2011 May.
Article in English | MEDLINE | ID: mdl-21595708

ABSTRACT

An implantable centrifugal blood pump has been developed with original features for a left ventricular assist device. This pump is part of a multicenter and international study with the objective to offer simple, affordable, and reliable devices to developing countries. Previous computational fluid dynamics investigations and wear evaluation in bearing system were performed followed by prototyping and in vitro tests. In addition, previous blood tests for assessment of normalized index of hemolysis show results of 0.0054±2.46 × 10⁻³ mg/100 L. An electromechanical actuator was tested in order to define the best motor topology and controller configuration. Three different topologies of brushless direct current motor (BLDCM) were analyzed. An electronic driver was tested in different situations, and the BLDCM had its mechanical properties tested in a dynamometer. Prior to evaluation of performance during in vivo animal studies, anatomical studies were necessary to achieve the best configuration and cannulation for left ventricular assistance. The results were considered satisfactory, and the next step is to test the performance of the device in vivo.


Subject(s)
Heart-Assist Devices , Hemodynamics , Prosthesis Implantation , Ventricular Function, Left , Animals , Biomechanical Phenomena , Brazil , Cattle , Male , Materials Testing , Prosthesis Design
5.
Artif Organs ; 35(5): 437-442, 2011. ilus, graf
Article in English | Sec. Est. Saúde SP, SESSP-IDPCPROD, Sec. Est. Saúde SP | ID: biblio-1060074

ABSTRACT

An implantable centrifugal blood pump hasbeen developed with original features for a left ventricularassist device. This pump is part of a multicenter and internationalstudy with the objective to offer simple, affordable,and reliable devices to developing countries. Previous computationalfluid dynamics investigations and wear evaluationin bearing system were performed followed byprototyping and in vitro tests. In addition, previous bloodtests for assessment of normalized index of hemolysis showresults of 0.0054 2.46 ¥ 10-3 mg/100 L. An electromechanicalactuator was tested in order to define the bestmotor topology and controller configuration. Three differenttopologies of brushless direct current motor (BLDCM)were analyzed.An electronic driver was tested in differentsituations, and the BLDCM had its mechanical propertiestested in a dynamometer. Prior to evaluation of performanceduring in vivo animal studies, anatomical studieswere necessary to achieve the best configuration and cannulationfor left ventricular assistance. The results wereconsidered satisfactory, and the next step is to test theperformance of the device in vivo.


Subject(s)
Heart-Assist Devices
6.
Rev. bras. eng. biomed ; 26(2): 99-104, ago. 2010. ilus, tab, graf
Article in English | LILACS | ID: lil-619156

ABSTRACT

O presente estudo tem a finalidade de avaliar o sistema de proteção dos dispositivos de retenção infantil, tais como a passagem do cinto de cinco pontos, referentes às tiras do torso e abdominais, e também avaliar a localização de componentes de proteção. Três modelos de dispositivos foram analisados em laboratório simulador no banco traseiro de veículo usando um dummy de três anos da família Hybrid III. A coleta de dados foi feita por meio de marcas predeterminadas no dummy e nos dispositivos e registradas tridimensionalmente por um equipamento digitalizador de pontos em 3D (FaroArm). Para isso, o dummy foi instalado nos assentos após sua fixação no carro seguindo os padrões da norma norte-americana nº 213, da Federal Motor Vehicle Safety Standard – FMVSS “Child Restraint Systems” (NHTSA, 2005). Os resultados mostraram uma grande variação no posicionamento dos componentes de proteção entre os modelos analisados. O cinto do torso apresentou diferenças em sua passagem no tórax superior conforme a altura de regulagem. A posição do cinto abdominal também variou entre os modelos, sendo observada a passagem do mesmo na região do abdômen ao invés de locais mais rígidos, como os ossos da pélvis. Além disso, a localização do componente lateral de proteção da cabeça sofreu grande variação em relação ao centro de gravidade de cabeça do dummy, indicando que, em alguns casos, a cabeça da criança pode não ser protegida lateralmente por se deslocar amplamente no caso de impacto lateral do carro, o que provocaria lesão. Os resultados deste trabalho sugerem que o design de assentos infantis ainda apresenta falhas quanto ao posicionamento dos componentes de proteção em relação às características anatômicas da criança, considerando a ampla faixa etária para que são fabricados.


A material suitable for craniofacial reconstruction must be easy to implant, have the appropriate shape, have the strength and deformation similar to the original bone, be eventually substitutedfor natural bone, be widely available and present affordable costs. As such as material, with all theses characteristics is still not available, it is important to search for new materials, new compositions and new design. Different biomaterials are used nowadays for craniofacial reconstruction surgeries, each one presenting its advantages and limitations. Among these materials are the titanium, the poli(methilmetacrilate) and the calcium phosphate cements. Titanium presents hard conformation; poli(methilmetacrilate)’spolymerization reaction is exothermic, which may cause necrosis of the adjacent tissues; calcium phosphate cement is brittle, an usual characteristic of ceramic materials. In this way, this study evaluated different materials used for craniofacial reconstruction and its mechanical properties when submitted to bending test, such as poli(methilmetacrilate), calcium phosphate cement and calcium phosphate cement reinforced with titanium. It was verified the improvement in the mechanical properties of the calcium phosphatecement when reinforced with titanium mesh. In addition, this study presents a method for design and manufacturing of customized craniofacial implants using calcium phosphate cement reinforced with titanium mesh, validated through four cases of craniofacial reconstruction surgery indication.


Subject(s)
Humans , Male , Female , Infant , Child, Preschool , Child , Seat Belts/classification , Seat Belts , Seat Belts , Child Restraint Systems/classification , Child Restraint Systems , Child Restraint Systems/adverse effects , Child Restraint Systems , Equipment Failure Analysis , Quality Control , Equipment Safety
7.
Artif Organs ; 32(4): 329-33, 2008 Apr.
Article in English | MEDLINE | ID: mdl-18370949

ABSTRACT

A new dual impeller centrifugal blood pump has been developed as a research collaboration between Baylor College of Medicine and Institute Dante Pazzanese of Cardiology for long-term left ventricle assist device (LVAD). A design feature of this new pump is a dual impeller that aims to minimize a stagnant flow pattern around the inlet port. Several different materials were tested in order to adopt a double pivot bearing design originally developed by Prof. Dr. Yukihiko Nosé from Baylor College of Medicine. Hydraulic performance tests were conducted with two different inlet ports' angle configurations 30 degrees and 45 degrees . Pump with inlet port angle of 45 degrees achieved best values of pressure ahead and flow after 1800 rpm. Preliminary hemolysis tests were conducted using human blood. The pump showed good performance results and no alarming trace of hemolysis, proving to be a feasible long-term LVAD.


Subject(s)
Biocompatible Materials , Ceramics/chemistry , Heart-Assist Devices/adverse effects , Hemolysis , Polymers/chemistry , Centrifugation , Equipment Design , Feasibility Studies , Hemorheology , Humans , Materials Testing , Pilot Projects , Pressure , Rotation , Stress, Mechanical , Time Factors
8.
Artificial Organs ; 32(04): 329-333, 2008. ilus
Article in English | Sec. Est. Saúde SP, SESSP-IDPCPROD, Sec. Est. Saúde SP | ID: biblio-1060088

ABSTRACT

A new dual impeller centrifugal blood pump has been developed as a research collaboration between Baylor College of Medicine and Institute Dante Pazzanese of Cardiology for long-term left ventricle assist device (LVAD).A design feature of this new pump is a dual impeller that aims to minimize a stagnant flow pattern around the inlet port. Several different materials were tested in order to adopt a double pivot bearing design originally developed by Prof. Dr. Yukihiko Nosé from Baylor College of Medicine. Hydraulic performance tests were conducted with two different inlet ports’ angle configurations 30° and 45°. Pump with inlet port angle of 45° achieved best values of pressure ahead and flow after 1800 rpm. Preliminary hemolysis tests were conducted using human blood. The pump showed good performance results and no alarming trace of hemolysis, proving to be a feasible long-term LVAD.


Subject(s)
Centrifugal Pumps , Ventricular Dysfunction, Left
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