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Klin Lab Diagn ; 59(12): 20-4, 2014 Dec.
Article in Russian | MEDLINE | ID: mdl-25872263

ABSTRACT

The study sampling included 46 patients operated on the occasion of acute surgical pathology of abdominal organs. The concentration of procalcitonin was analyzed at 2-3 days after operation in simultaneously obtained samples of blood serum and exudation of small intestine. The level of procalcitonin was analyzed using enzyme-linked immunosorbent assay with test-systems with sensitivity 0.01 ng/ml. The concentration of procalcitonin in content of small intestine was lower than in blood serum (p<0.001) and in most samples of enteric exudation (n=33) did not exceed 0.01 ng/ml. The analysis of correlation interdependences established that concentration of procalcitonin in intestinal exudation has no dependencies with its level in blood serum. The admixture of blood as a result of traumatization of mucous membrane under application of naso-jejunal probe is one of main causes of occurrence of procalcitonin in content of intestine.


Subject(s)
Abdomen/surgery , Calcitonin/blood , Intestine, Small/surgery , Protein Precursors/blood , Abdomen/pathology , Adult , Aged , Calcitonin Gene-Related Peptide , Exudates and Transudates/metabolism , Female , Humans , Intestine, Small/metabolism , Intestine, Small/pathology , Male , Middle Aged , Postoperative Period
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