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1.
Otol Neurotol ; 41(8): 1108-1115, 2020 09.
Article in English | MEDLINE | ID: mdl-32740544

ABSTRACT

OBJECTIVE: To determine the feasibility of a patient-specific, three-dimensionally (3D)-printed reconstruction plate for repair of lateral skull base defects. STUDY DESIGN: Prospective case series and cadaveric study. SETTING: A university-based, tertiary care hospital. PATIENTS: Three patients with lateral skull base defects and five cadavers. MAIN OUTCOME MEASURE(S): Caliper gauge fit testing was performed in the cadaver temporal bones to determine the fit of the tegmen plate in engaging the tegmen defect. Additionally, three patients underwent standard of care reconstruction of their middle fossa floor using autografts or allografts. Temporary plate insertion during standard operative repair was performed to gauge feasibility and fit. Operative time required for standard grafting compared with placement of the tegmen plate was examined. RESULTS: Real-time, intraoperative placement of the tegmen plate in our patients under 1 minute compared with nearly 60 minutes for standard surgical repair. Tegmen plates covered the defects and locked into place from contour matching without impinging on critical structures. Fit testing revealed flush-fitting plates to the cadaveric temporal bone surface with all gaps less than 500 µm. CONCLUSIONS: Computer modeling and 3D printing can design custom fitted tegmen reconstruction plates for temporal bone defects. Versatility in prefabrication and 3D modeling shows potential in allowing the construct to avoid critical structures and adequately cover defects with high precision to the tegmen surface.


Subject(s)
Skull Base , Temporal Bone , Bone Plates , Humans , Printing, Three-Dimensional , Prospective Studies , Skull Base/diagnostic imaging , Skull Base/surgery , Temporal Bone/diagnostic imaging , Temporal Bone/surgery
2.
Otol Neurotol ; 34(9): 1615-21, 2013 Dec.
Article in English | MEDLINE | ID: mdl-24232062

ABSTRACT

OBJECTIVE: Children with auditory neuropathy (AN) have variable hearing on pure tone testing, and the presence of speech and language delays often play a major role in the decision to offer cochlear implantation (CI) in this population. Despite this fact, the speech and language outcomes in this group after CI are not well described. This study compares speech and language outcomes after CI in a subset of the pediatric AN population that does not have a confounding cognitive disorder with those of their peers with cochlear hearing loss (CoHL). STUDY DESIGN: Retrospective chart review. SETTING: Tertiary referral center. PATIENTS: Seventeen pediatric patients with AN who received a CI and a group of children with CoHL who received a CI were the subjects of this study. The 2 groups demonstrated similar ages at implant. Children with cognitive delays were excluded from each group. INTERVENTION: Cochlear implantation. MAIN OUTCOME MEASURES: All subjects were evaluated preoperatively and postoperatively with standardized age appropriate speech and language measures, including the Expressive Vocabulary Test (EVT), Peabody Picture Vocabulary Test (PPVT), and Preschool Language Scale (PLS). RESULTS: There was no significant difference between the groups on age of activation of the CI. Children with a diagnosis of AN had a significantly lower unaided pure tone average preoperatively as compared with children with cochlear hearing loss; however, there was no significant difference between the groups on either their preimplantation or postimplantation speech and language scores. CONCLUSION: Children with a diagnosis of AN without associated cognitive or developmental disorders have speech and language outcomes comparable to other children who received a CI.


Subject(s)
Cochlear Implantation , Hearing Loss, Central/surgery , Hearing Loss, Sensorineural/surgery , Language Development , Language , Speech/physiology , Child , Child, Preschool , Cochlear Implants , Female , Hearing Loss, Central/physiopathology , Hearing Loss, Sensorineural/physiopathology , Humans , Infant , Male , Retrospective Studies , Speech Perception/physiology , Treatment Outcome
3.
Otol Neurotol ; 34(3): 477-83, 2013 Apr.
Article in English | MEDLINE | ID: mdl-23478650

ABSTRACT

OBJECTIVE: Auditory neuropathy (AN) is a heterogeneous clinical entity for which the optimal method of auditory rehabilitation has been a matter of some debate. Such patients often do not receive sufficient benefit from hearing aids. Previous studies have shown that select AN patients may benefit from cochlear implantation (CI), but reported outcomes are variable and likely are a reflection of the heterogeneous patient population included under the umbrella diagnosis of AN. This study compares CI outcomes in a subset of the pediatric AN population who do not have a confounding cognitive disorder with their cochlear hearing loss peers. Additionally, it examines the impact of a confounding cognitive or developmental disorder on CI outcomes within the AN population. STUDY DESIGN: Retrospective chart review. SETTING: Tertiary referral center. PATIENTS: Twenty-six pediatric patients with AN who received a CI were the subjects of this study. Seventeen of these children had a diagnosis of AN alone, and their CI outcomes were compared with those of a similar group of children with cochlear hearing loss. The remaining 9 children had a diagnosis of AN in association with a confounding cognitive or developmental disorder, and their CI outcomes were compared with those of children with isolated AN. INTERVENTION: Cochlear implantation. MAIN OUTCOME MEASURES: All subjects were evaluated preoperatively and postoperatively with age-appropriate speech perception testing. RESULTS: Children with a diagnosis of AN alone performed comparably to their peers with cochlear hearing loss. The presence of a confounding cognitive or developmental disorder within the AN population was correlated with significantly poorer CI outcomes as compared with those of children with isolated AN. CONCLUSION: Children with a diagnosis of AN without associated cognitive or developmental disorders perform at a level comparable to other children requiring a CI. Children with a diagnosis of AN associated with other developmental anomalies derive some benefit from CI but are significantly more likely to continue to rely on nonoral/aural methods of communication after implantation.


Subject(s)
Cochlear Implantation , Hearing Loss, Central/surgery , Hearing Loss, Sensorineural/surgery , Speech Perception/physiology , Child , Child, Preschool , Cochlear Implants , Female , Hearing Loss, Central/physiopathology , Hearing Loss, Sensorineural/physiopathology , Humans , Infant , Language Development , Male , Retrospective Studies , Treatment Outcome
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