ABSTRACT
Results of surgical treatment of 346 patients with cancer of the stomach are presented. All the patients underwent extended D2 and D3 lymphadenectomy. Up-to-date aspects of surgical treatment of stomach cancer, including intraoperative staging of cancer, spectrum of surgeries, their technical features, postoperative complications, lethality are outlined. Extended lymphadenectomy increases insignificantly time of surgery, rate of postoperative complications, postoperative lethality compared with standard surgeries in cancer of the stomach.
Subject(s)
Gastrectomy/methods , Lymph Nodes/surgery , Stomach Neoplasms/pathology , Stomach Neoplasms/surgery , Adult , Aged , Female , Gastrectomy/adverse effects , Gastrectomy/mortality , Humans , Lymph Node Excision , Male , Middle Aged , Neoplasm Invasiveness/diagnosis , Peritoneal Cavity/surgery , Stomach Neoplasms/diagnosis , Treatment OutcomeABSTRACT
The results of surgical treatment in 120 patients with cancer of the stomach have been analyzed. Metastatic involvement in all groups of lymphatic nodes was revealed in 68.3% cases, retroperitoneal metastases were detected in 46 patients (38.3%). 38 subtotal resections of the stomach and 82 gastrectomies with retroperitoneal lymphadenectomy R2 and R3 were performed. Esophagojejunoanastomosis end-to-end with a loop excluded by Roux was applied in 110 patients and esophagoduodenoanastomosis--in 10 patients. Insufficiency of esophagointestinal anastomosis was revealed in 3 patients. The rate of complications was 29.2%, lethality--8.3%. High rate of postoperative complications and lethality were explained by initially severe conditions of the patients (61%) and by complicated forms of gastric cancer in 6 patients. Improvement of early results of surgical interventions lies in the usage of antibacterial prophylaxis, preventive intravenous introductions of 5-fluorouracil, adequate drainage of the abdominal cavity, careful preparation and ligation in the course of the operation.
Subject(s)
Lymph Node Excision/methods , Stomach Neoplasms/surgery , Humans , Lymphatic Metastasis , Peritoneal CavityABSTRACT
Phenotypes and genes of the serum haptoglobin (HP) system were studied in connection with antigens of the systems ABO, Rhesus (D), Pp, MN, and Gm and with the sex of probands from the Armenian population. The data are compared with similar studies on some populations of the Caucasus, Asia, Europe, America, and Africa. Comparative analysis revealed some peculiarities of the studied phenotype distribution in the population of Armenians from Armenia. The A phenotype of the ABO system is shown to be positively associated with the HP1-1 variant.
