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1.
J Pharm Bioallied Sci ; 14(Suppl 1): S868-S871, 2022 Jul.
Article in English | MEDLINE | ID: mdl-36110734

ABSTRACT

Background: Surgery site infections (SSIs) are infections that arise in surgery for an operative wound infection surveillance within 30 days of surgery or 90 days after implant installation. JNMC, Bhagalpur, India, intended to look at the pre- and postoperative use of antibiotics. Methods: Four hundred twelve patient charts were analyzed for four months in JNMC, Bhagalpur, India as part of a hospital-based cross-section study. The study covered all patients 13 years of age and older who had been admitted to the hospital and had undergone various surgeries. In addition, a P value was preserved for the further multivariate analysis, using multiple logistic regressions, to study the association between the resulting variable and the predictor. Results: The general surgery operation included 152 of the 412 patients, while the remainder was for different operations. A single operative antibiotic was administered to the majority of patients, followed by two surgical prophylactic medications. Before the hospital was discharged, 40 of the patients experienced surgical site infections. In almost half of these cases, ceftriaxone and metronidazole were combined with SSIs. Emergency surgery patients were 2.6 times more likely to have a SSI than optional surgery patients. The SSIs were 2.5 times more likely in patients who were not given antibiotic prophylaxis. In our investigation, the protection against SSI was found to include clean-contaminated and contaminated wound types. Conclusions: According to this study, the majority of patients received antimicrobial prophylaxis. In the hospital where the study was done, the total incidence of SSIs was 11.1%. The most frequently given antibiotic was ceftriaxone. The absence of prevention, wound type, and types of surgery has all been associated with SSI development.

2.
Bioinformation ; 18(10): 962-967, 2022.
Article in English | MEDLINE | ID: mdl-37654830

ABSTRACT

This study was carried out to assess the clinical and bacterial profiles of abdominal surgery site infections in a tertiary care hospital.Samples recovered from infected wounds at abdominal surgery sites were processed using highly advanced microbiological procedures. To process these samples, the most recently accepted standard CLSI guidelines were used. Antimicrobial vulnerability was investigated using a modified Kirby-Bauer disc diffusion method.97 samples were collected from 83 patients who had proven evidence of infections at abdominal surgery sites. It was found that 97.5% of the total samples had evidence of significant growth of bacteria and bacterial isolates obtained were 88 in number. Staphylococcus aureus was the most often isolated bacterium, accounting for 51.52% of total samples. The second most prevalent germ isolated was Escherichia coli, which accounted for 24.13% of total samples. It was concluded that the high prevalence of infections at the surgical sites of abdomen in our study highlights the importance of providing high-quality surgical care that considers the features of the host, environment, and microorganisms before performing any surgery.

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