ABSTRACT
The etiological pattern of respiratory viral infections was detected in Baku in 2002-2006. There was a high proportion of influenza A virus in the occurrence of respiratory infections in Baku in 2002-2006. There was no relationship of the detection of various respiratory viral infections to age and sex in Baku in the above period.
Subject(s)
Respiratory Tract Infections/epidemiology , Virus Diseases/epidemiology , Acute Disease , Adenoviridae/isolation & purification , Adult , Azerbaijan/epidemiology , Child , Comorbidity , Enterovirus/isolation & purification , Female , Humans , Influenza A virus/isolation & purification , Male , Respiratory Syncytial Viruses/isolation & purification , Respiratory Tract Infections/virology , Urban Population , Virus Diseases/virologyABSTRACT
Transplanted human amnion cells have been used in experiments differing in the regularity of the sodium fluoride and alpha-tocopherol action to determine a considerable antimutagenic efficiency of the mutagenic process modifier, the efficiency being dependent on the treatment variability.
Subject(s)
DNA Damage , Mutagens , Sodium Fluoride/toxicity , Vitamin E/pharmacology , Amnion/cytology , Amnion/drug effects , Female , Humans , Pregnancy , Sodium Fluoride/antagonists & inhibitorsABSTRACT
The ability of alpha-tocopherol to neutralize mutational process caused by persistent infection (West Nile virus, strain 229) and primary infection (virus of poliomyelitis, type II) was shown in transplanted amnion and human kidney cells. Antimutagenic effect of the modificator was registered, independently of the regime and succession of applying alpha-tocopherol and inductors.
Subject(s)
Cell Transformation, Viral/drug effects , Mutation , Poliovirus/genetics , Vitamin E/pharmacology , West Nile virus/genetics , Humans , Poliovirus/pathogenicity , Virulence , West Nile virus/pathogenicityABSTRACT
The incidence of chromosome aberrations in bone marrow cells of femur did not exceed the spontaneous one in CBA mice exposed, during 70 days, to gamma-radiation at dose--rates of 33.7-35.8 nA/kg and cumulative dose of 2.75 Gy. A single acute exposure of intact animals to a dose of 2.98 Gy increased significantly the mutation level. Preirradiation with small doses increased the resistance of hereditary structures to sublethal radiation doses. Exogenous alpha-tocopherol (0.06 mg/20 g mass) protected the genetic apparatus of cells from total-body irradiation and was an additional factor decreasing the mutation level after acute exposure of mice at the background of long-term irradiation with small doses.
