ABSTRACT
A 69-year-old man with a past history of right middle cerebral artery (MCA) occlusion had cerebral single photon emission computed tomography (SPECT) with technetium-99m ethyl cysteinate dimer (Tc-99m ECD). Dynamic SPECT in the super-early phase revealed normal uptake in the left cerebellum and hypoactivity in the right MCA territory. Conventional static SPECT revealed decreased cerebral blood flow in the right MCA territory and the left cerebellum, indicating crossed cerebellar diaschisis. Our SPECT studies revealed decreased retention of Tc-99m ECD in the cerebellum manifested as crossed cerebellar diaschisis.
Subject(s)
Cerebellum/blood supply , Cerebellum/diagnostic imaging , Cysteine/analogs & derivatives , Organotechnetium Compounds , Radiopharmaceuticals , Tomography, Emission-Computed, Single-Photon , Aged , Cerebrovascular Circulation , Humans , MaleABSTRACT
We present a 21-year-old woman with tumefactive multiple sclerosis (MS) that exhibited a rapidly progressive course. There were multiple tumor-mimicking contrast-enhance lesions with surrounding edema and mass effect on magnetic resonance imaging. Both early and delayed brain single photon emission computed tomography (SPECT) with N-isopropyl-p-[123I]-iodoamphetamine demonstrated increased accumulations of the tracer and a high retention on the lesions. The SPECT findings represent a diagnostic pitfall for distinguishing MS from malignant brain tumors in patients with intracranial tumor-like lesions.
Subject(s)
Brain/diagnostic imaging , Brain/metabolism , Diagnostic Errors/prevention & control , Iofetamine/pharmacokinetics , Multiple Sclerosis, Chronic Progressive/diagnostic imaging , Multiple Sclerosis, Chronic Progressive/metabolism , Adult , Brain/pathology , Brain Neoplasms/diagnostic imaging , Brain Neoplasms/metabolism , Diagnosis, Differential , Female , Humans , Magnetic Resonance Imaging , Multiple Sclerosis, Chronic Progressive/pathology , Radiopharmaceuticals/pharmacokinetics , Tomography, Emission-Computed, Single-Photon/methodsABSTRACT
A 12-year-old girl presented with Kasabach-Meritte syndrome associated with anterior mediastinal hemangioma. 111In-oxine-labeled platelet scintigraphy and 99mTc-HSA-D scintigraphy were very useful for the diagnosis and evaluation of this condition.
Subject(s)
Hemangioma/complications , Hemangioma/diagnostic imaging , Indium Radioisotopes , Mediastinal Neoplasms/complications , Mediastinal Neoplasms/diagnostic imaging , Technetium Tc 99m Aggregated Albumin , Technetium Tc 99m Pentetate , Thrombocytopenia/etiology , Blood Platelets , Child , Female , Humans , Radionuclide Imaging , Thrombocytopenia/diagnostic imagingSubject(s)
Acetazolamide , Brain/diagnostic imaging , Carotid Artery, Internal/abnormalities , Radiopharmaceuticals , Technetium Tc 99m Exametazime , Tomography, Emission-Computed, Single-Photon , Carotid Artery, Internal/diagnostic imaging , Humans , Magnetic Resonance Angiography , Male , Middle AgedABSTRACT
We present an autopsy case of primary leptomeningeal melanoma visualized with technetium-99m-hexamethylpropyleneamine oxime (Tc-99m-HMPAO) single photon emission CT (SPECT) of the brain. Increased uptake of Tc-99m-HMPAO coincided with leptomeningeal enhancement on MR images and with the tumor location of the autopsy findings. It was thought that Tc-99m-HMPAO could correlate closely with melanoma. Tc-99m-HMPAO SPECT clearly showed primary leptomeningeal melanoma and severe hypoperfusion induced by intracranial hypertension and tumor proliferation.
Subject(s)
Melanoma/diagnosis , Meningeal Neoplasms/diagnosis , Technetium Tc 99m Exametazime , Adult , Fatal Outcome , Humans , Male , Melanoma/surgery , Meningeal Neoplasms/surgery , Tomography, Emission-Computed, Single-PhotonABSTRACT
This patient was a 70-year-old man had acute subendocardial infarction in the inferior wall. 123I-BMIPP myocardial scintigraphy showed no accumulation in the myocardium. 123I-MIBG myocardial scintigraphy on the early and delay images and 99mTc-tetrofosmin myocardial scintigraphy at rest showed slightly decreased accumulation of the tracer in the apical region and in middle inferior wall of the left ventricle, indicating subendocardial infracted area. In the examinations of CD36 in platelets and monocytes, the patient had negative CD36 in platelets and monocytes, and type I CD36 deficiency was diagnosed. We supposed that no 123I-BMIPP accumulation may be related closely to type I CD36 deficiency.
