ABSTRACT
The authors experienced a case with obstruction of the inferior vena cava (IVC) and the common bile duct due to a recurrent hepatocellular carcinoma. In order to improve severe edema of the lower extremities and obstructive jaundice, IVC metallic stent as well as biliary stent were applied. A Luminexx stent of 8 cm in length was placed in the bile duct via subcutaneous route after biliary drainage. A spiral zigzag stent of 8 cm in length was also inserted into the IVC through the femoral vein following balloon dilatation of the obstructed portion. Subsequently, jaundice and edema were dramatically improved in a short period of time, which resulted in patient discharge from the hospital. Although the patient died of the cancer in 2 months, the quality of life was well maintained until death.
Subject(s)
Carcinoma, Hepatocellular/complications , Cholestasis/therapy , Common Bile Duct , Liver Neoplasms/complications , Stents , Vena Cava, Inferior , Adult , Catheterization , Humans , Male , Neoplasm Recurrence, Local , Quality of Life , Vascular Diseases/therapyABSTRACT
A 38-year-old man had multiple recurrence of hepatocellular carcinoma (HCC) with portal vein thrombosis after hepatectomy and postoperative transcatheter arterial chemotherapy with 5-fluorouracil (5-FU). He was treated by trans hepatic arterial embolization (TAE) with 100 mg of cisplatin (CDDP) and degrable starch microspheres (DSM). After 3 courses were administered, the recurrent lesions almost disappeared on CT, and the postoperative rise in PIVKA-II level and AFP level normalized. There were no side effects except slight fever and general fatigue. We recognized a partial response, and the patient is still alive 14 months after hepatectomy. This case suggests that TAE with CDDP and DSM might be useful for prolonging the survival of advanced HCC patients.
Subject(s)
Antineoplastic Agents/administration & dosage , Biomarkers , Carcinoma, Hepatocellular/therapy , Chemoembolization, Therapeutic , Cisplatin/administration & dosage , Liver Neoplasms/therapy , Starch/administration & dosage , Adult , Biomarkers, Tumor/blood , Carcinoma, Hepatocellular/blood , Drug Administration Schedule , Hepatectomy , Hepatic Artery , Humans , Infusion Pumps, Implantable , Infusions, Intra-Arterial , Liver Neoplasms/blood , Male , Neoplasm Recurrence, Local/therapy , Portal Vein , Protein Precursors/blood , Prothrombin , Thrombosis/etiologyABSTRACT
The authors investigated the usefulness of W-Spiral Catheters for adjuvant hepatic arterial infusion (HAI) chemotherapy following curative resection of colorectal liver metastases. The catheter has a special shape-memory alloy in its tip, which allows preferable fixation without coils and removal of the catheter if desired. A W-spiral catheter was successfully placed in 13 out of 16 patients who had undergone curative hepatectomy. In the remaining 3 cases in which the hepatic artery was smaller in diameter, a catheter was placed using the conventional GDA coiling method. Removal of the W-Spiral Catheter was attempted in 10 of the 13 patients with a Spiral Catheter after termination of HAI chemotherapy. In all cases, the catheters were easily and uneventfully removed, and 3D-CT angiography revealed that the hepatic artery was well preserved in most cases. These findings suggest that a new approach to prophylactic HAI chemotherapy with W-Spiral Catheters and subsequent removal of the catheters is reasonable and desirable.
