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Ukr Biokhim Zh (1978) ; 69(4): 111-4, 1997.
Article in Russian | MEDLINE | ID: mdl-9583134

ABSTRACT

The processes of lipids free-radical oxidation in euthyroid and thyrotoxic tissue samples of human thyroid gland were studied. It was shown, that the content of TBA-active lipid peroxidation products was considerably increased in thyrotoxic tissue of the thyroid, and the activity of antioxidant enzymes (catalase, glutation peroxidase) was decreased in it. Possible mechanism of the tissue lipoperoxide alternation under conditions of the thyroid hyperfunction is discussed.


Subject(s)
Graves Disease/metabolism , Lipid Peroxidation , Thyroid Gland/metabolism , Catalase/analysis , Free Radicals , Glutathione Peroxidase/analysis , Graves Disease/blood , Humans , Thiobarbituric Acid Reactive Substances/analysis , Thyroid Gland/enzymology , Thyroxine/blood , Triiodothyronine/blood
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