ABSTRACT
We present our prospective comparative study on 60 patients subjected to two types of gastric restrictive procedures, i.e. Vertical Banded Gastroplasty (VBG) and Laparoscopic Adjustable Gastric Banding (LAGB) at King Abdul Aziz University Hospital, Jeddah, Saudi Arabia. The aim of our study was to compare weight reduction after both procedures. Thirty patients had VBG and thirty had LAGB based upon informed consents. The age, sex and preoperative weight and BMI were comparable in both groups. Excess weight loss of 87% was achieved in the VBG group while only 50% was noticed in the LAGB group at 6 months postoperatively.
Subject(s)
Gastroplasty/methods , Laparoscopy , Obesity, Morbid/surgery , Adult , Controlled Clinical Trials as Topic , Female , Humans , Male , Prospective Studies , Weight LossABSTRACT
Several methods have been propsed to assess nutritional status of patients in relation to post-operative complications including instant nutritional assessment (INA) and prognostic nutritional index (PNI). Weight loss (WL) has also been related to post-operative morbidity. A prospective study was conducted to evaluate the prognostic ability of INA, PNI and WL in 300 patients affected by major and semi-major surgeries. Post-operative sepsis occurred in 28 (9.3%) patients. Of the 300 patients studied, 91 (30.2%) had WL 10%; 12 patients were septic. Of the 28 septic patients indentified, 24 (85.7%) were within the high-risk group as identified by PNI characterisation. When both serum albumin and total lymphocyte count were abnormal, sepsis rate was 100%. All methods had a Youden index greater than one. Therefore, WL should be the first parameter assessed, and if WL is > 10%, then INA can be used to assess the patient further.
ABSTRACT
A prospective study was conducted on paediatric thermal injury patients admitted to the Burns Unit at King Fahd Hospital, Jeddah, Saudi Arabia over a 2-year period (December 1985 to December 1987). A total of 197 patients (out of 319) were paediatric, aged up to 18 years. Infants and toddlers accounted for 59.4 per cent and adolescents for 14.2 per cent. Scalding and flame injuries accounted for 98 per cent with most injuries occurring at home (97.5 per cent) and the overall paediatric mortality rate was 4.4 per cent.
Subject(s)
Burns/epidemiology , Accidents, Home , Adolescent , Age Factors , Body Surface Area , Burns/etiology , Burns/mortality , Burns/therapy , Burns, Chemical/epidemiology , Burns, Electric/epidemiology , Child , Child, Preschool , Female , Humans , Infant , Male , Prospective Studies , Saudi Arabia/epidemiology , Seasons , Sepsis/mortality , Sex Factors , Skin TransplantationABSTRACT
The Abbott TDx fluorescence polarization immunoassay (FPIA) system has been evaluated and compared with well-established high performance liquid chromatography (HPLC) for the determination of three anticonvulsant drugs: phenytoin, phenobarbitone and carbamazepine. These assays were evaluated for precision, calibration curve stability, specificity and accuracy. Within-run precision studies using control samples (n = 15) in the subtherapeutic, therapeutic, and toxic concentrations, resulted in coefficients of variation in the range of 1.79-3.99% (FPIA) and 1.16-2.52% (HPLC), respectively. Between-run precision ranged from 2.32-6.34% for FPIA and from 2.04-3.38% for HPLC. Comparison of 122 patient samples assayed with both methods indicated an extremely good analytical correlation (r = 0.96) for all three comparisons. The FPIA method offers significant advantages in calibration curve stability while maintaining accuracy and precision comparable with those of established HPLC procedures.
