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Ocul Immunol Inflamm ; 27(8): 1235-1241, 2019.
Article in English | MEDLINE | ID: mdl-31411519

ABSTRACT

Purpose: To evaluate the efficacy and safety of posterior 40 mg subtenon triamcinolone acetonide (PST) injection in treating Irvine-Gass syndrome.Methods: The retrospective study included 21 patients (mean age: 76 ± 8.2) with a treatment-naïve eye subjected to topical anesthesia and injection of 40 mg/ml triamcinolone via a blunt tip SubTenon cannula through a single inferonasal peritomy. Best corrected visual acuity (BCVA; logMAR), intraocular pressure (IOP), biomicroscopic and funduscopic findings, and optical coherence tomography (OCT) measurements were recorded.Results: Baseline central macular thickness decreased from 431 ± 136 µm to 300 ± 67 µm (1st month; p = .002), to 292 ± 56 µm (3rd month; p = .002), and to 299 ± 66 µm (6th month; p = .005). Mean BCVA increased from 0.71 ± 0.23 to 0.27 ± 0.11, 0.19 ± 0.06, and 0.24 ± 0.17, respectively (all visits; p < 0.001). Mean IOP values did not change significantly (p = .12).Conclusion: PST injection is an effective and safe treatment for Irvine-Gass syndrome.


Subject(s)
Macula Lutea/pathology , Macular Edema/drug therapy , Triamcinolone Acetonide/administration & dosage , Visual Acuity , Aged , Female , Fluorescein Angiography/methods , Follow-Up Studies , Fundus Oculi , Glucocorticoids/administration & dosage , Humans , Injections, Intraocular , Macular Edema/diagnosis , Male , Retrospective Studies , Tenon Capsule , Tomography, Optical Coherence/methods , Treatment Outcome
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