ABSTRACT
Nasal mucociliary clearance time (NMCT) is prolonged in patients with olfactory disorders. It is essential to differentially diagnose conductive and neural olfactory disorders. Here, we used the mucociliary clearance test to investigate a disease associated with neural olfactory disorders, i.e. schizophrenia. Data on age, gender, and duration of disease were collected. The study involved 56 schizophrenia patients and 56 healthy controls. There was no significant difference between the groups regarding age and gender (p = 0.459 and p = 0.768 respectively). Mean NMCT of patients with schizophrenia was 13.82 ± 3.22 min and mean NMCT of healthy controls was 10.15 ± 2.94 min. There was significant difference between the groups regarding NMCT (p < 0.001). In the patient group, there was a significant positive correlation between duration of disease, age, and NMCT (Pearson r = 0.286, p = 0.032, and Pearson r = 0.522, p < 0.001 respectively). This study has shown a prolonged NMCT in patients with schizophrenia compared to the healthy control group.
ABSTRACT
This clinical study aimed to compare the mucociliary clearance time in patients with OCD, a disease associated with neural olfactory disorders, with a healthy control group. The mucociliary clearance time of fifty-one patients with OCD and fifty-two healthy patients (control group) was compared. The saccharin nasal mucociliary clearance test (NMCT) was applied and recorded the sociodemographic data of all participants. The NMCT was longer in OCD patients than healthy controls. There was no statistically significant difference in sociodemographic data between the groups. Our results show that olfactory transmission pathways may be affected in OCD patients. Supplementary Information: The online version contains supplementary material available at 10.1007/s12070-023-03972-2.
