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1.
Cureus ; 16(5): e59753, 2024 May.
Article in English | MEDLINE | ID: mdl-38840991

ABSTRACT

BACKGROUND: Tinea pedis, commonly known as athlete's foot, is a fungal infection affecting the skin of the feet, primarily between the toes. Despite being a common condition, there may be gaps in knowledge and practices regarding its transmission, risk factors, and treatment options among the general population. METHODS: This study adopted a cross-sectional research design. The study involved 2371 adult population in Saudi Arabia. The questionnaire was distributed online through social media means. Data was analyzed using IBM SPSS Statistics for Windows, Version 27 (Released 2020; IBM Corp., Armonk, New York, United States). RESULTS: A significant portion (66.1%) of respondents reported not examining their feet regularly. The majority (80.7%) of the respondents reported regular use of nail scissors as the common practice. The results further revealed that the majority of respondents (71.7%) were not aware of tinea pedis. Similarly, a large proportion (77.3%) of respondents were unaware of the risk factors associated with tinea pedis. However, among those aware, the most recognized risk factor was diabetes mellitus (82.3%), followed by peripheral arterial disease (37.1%), and immunocompromised conditions like HIV (31.3%). There was a significant association (p = 0.001) between regular foot examination practices and awareness of tinea pedis. CONCLUSION: In conclusion, there is low awareness regarding tinea pedis among the Saudi Arabian population. Only a small proportion demonstrated good knowledge of the condition and its symptoms. However, there is a relatively higher awareness of specific risk factors such as diabetes mellitus and peripheral arterial disease. Hence, it is imperative to enhance education and awareness campaigns to address the gaps in understanding tinea pedis, its associated risk factors, and symptoms, particularly among individuals engaged in physical activities and those who regularly wear sports shoes.

2.
Cureus ; 16(3): e57085, 2024 Mar.
Article in English | MEDLINE | ID: mdl-38681262

ABSTRACT

Rosacea is a common cutaneous condition caused by persistent, recurring lesions in facial skin vessels. It is a chronic skin condition with a variety of clinical symptoms and an unknown cause. Rosacea begins with the widening of capillaries and a flushed appearance. Following that, telangiectasia appears, and reddened patches persist, particularly on the cheeks and nose. Erythema persists due to repeated vasodilation and telangiectasia. In addition, skin inflammation manifests as papules, pustules, lymphedema, and fibrosis. Despite recent advances in treatment, rosacea, a chronic inflammatory relapsing central facial dermatosis, can be extremely difficult to manage.  The purpose of this meta-analysis and systematic review was to evaluate the effectiveness of low-dose isotretinoin in the treatment of rosacea. Following the guidelines set forth by the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA), the researcher employed the following search terms in the EMBASE, Web of Science, PubMed, Cochrane Library, and Google Scholar databases to provide a therapeutic update relevant to clinical practice: "low dose isotretinoin," "isotretinoin and rosacea," "isotretinoin treatment of rosacea," and "effectiveness of isotretinoin in treating rosacea". The search was carried out by the researcher for articles published from February 2019 to February 2024. The articles included were all published in the English language. The overall frequency of patients with adverse events differed significantly between the groups treated with low-dose isotretinoin and the comparators (minocycline, pulsed dye laser, evening primrose oil, Lactobacillus plantarum, doxycycline, combined dose or placebo) (0.80, 95% CI 0.73 to 0.88, p = 0.0001). Sub-group analysis indicated that there was a difference between the interventions used in the treatments all in favor of low-dose isotretinoin treatment. The results showed that the moderate group had RR: 0.76, 95% CI: 0.44-1.30, I2 = 0%; the mild group had RR: 0.94, 95% CI: 0.56-1.57, I2 = 0%; and the group with severe rosacea had RR: 0.73, 95% CI: 0.47-1.13, I2 = 0%. According to this study, rosacea can be treated effectively with low-dose isotretinoin even in patients at severe stages of the disease by using the recommended dose once a week. Further, the intervention has also been shown to have fewer side effects on the patients. Therefore, this study recommends randomized controlled trials to be done to fully investigate the best combination options for isotretinoin on mild to severe rosacea based on the fact that some of the treatments combined have shown to be effective on treatment.

3.
Cureus ; 16(3): e55710, 2024 Mar.
Article in English | MEDLINE | ID: mdl-38586780

ABSTRACT

Introduction Skin photoaging is caused by prolonged exposure to sunlight, particularly ultraviolet rays (UV). High cumulative levels of UV radiation may cause burning, photoallergic or phototoxic reactions, pigmentary changes, photoaging, and even immunosuppression and skin cancers. Therefore, this study aims to assess knowledge, attitude, reception, and preventive practices towards skin photoaging among the Jazan general population in Saudi Arabia and its determinants. Methods A descriptive cross-sectional study was conducted among the general population of Jazan, Saudi Arabia, who were aged 18 years and above and agreed to participate in the study. The calculated minimum sample size was 385. An online, semi-structured, self-administered questionnaire was distributed conveniently in Google Forms through social media platforms. It included four sections: The first section was about sociodemographic characteristics. The second section assessed the smoking, exercise, and healthy diet behavior of participants and the use of sunscreen. The third section assessed the knowledge regarding the photoaging process and its preventive measures utilization using three-point Likert scale questions. The fourth section assessed attitudes towards the photoaging process and its preventive measures through three-point Likert scales. Results The study included 452, of which 243 (53.76%) were aged 18-30 years, 258 (57.08%) were females, and 272 (60.18%) had white skin color. Approximately 417 (92.26%) were nonsmokers. Sixty-eight percent (372) spent 1-3 hours in the sun. Social media was the primary source of information on photoaging 81 (17.92%). Around 234 (51.77%) defined photoaging correctly. Regarding sunscreen usage, 58 (12.83%) always use sunscreen, and 177 (39.16%) never use it. However, 191 (42.26%) recognized the correct sunscreen application. Approximately 233 (51.5%) and 240 (53.1%) of respondents had fair knowledge and a positive attitude regarding photoaging and sunscreen use. Being female, pursuing university and postgraduate education, and taking information on photoaging from a physician were linked to a higher knowledge of photoaging (p<0.05). Participants who never use sunscreen had lower knowledge than those who always use it (p<0.001). None of the demographic factors was associated with the attitude towards sunscreen use (p>0.05). Conclusion There is a substantial gap in knowledge and preventive practices related to skin photoaging among the Jazan general population in Saudi Arabia. Gender, education level, and information sources influence knowledge levels. Targeted educational interventions are needed to enhance awareness and promote healthier practices, particularly sun exposure and photoaging prevention.

4.
Cureus ; 15(11): e48398, 2023 Nov.
Article in English | MEDLINE | ID: mdl-38073910

ABSTRACT

BACKGROUND: Psoriasis is a worldwide disease. It is a chronic immune-mediated inflammatory disease with cutaneous and systemic symptoms that is characterized by erythematous squamous plaques. OBJECTIVES: To study the perception and assessment of psoriasis among the general population of Jazan, Saudi Arabia. MATERIALS AND METHODS: This was a cross-sectional study that used a self-administrated electronically distributed questionnaire that enrolled 410 people. RESULTS: Most participants (79%) were familiar with the term "psoriasis," with family, friends, or acquaintances being the primary source of knowledge. Personal experience with psoriasis was reported by 28.3% of participants, with women being more likely to know someone with the condition. If affected by psoriasis, the majority of respondents would consult a dermatologist (89.3%). Although 48% of participants considered psoriasis to be a significant burden for affected individuals, negative attitudes and discrimination towards those with the condition were prevalent, with a significant proportion stating that they would not want to eat at the same table, shake hands, or be in a personal relationship with someone with psoriasis. Additionally, most participants reported feeling sorry for psoriasis patients but also expressed disgust towards them. Awareness of public actions related to psoriasis was generally low, with only a small percentage of participants familiar with the WHO resolution on psoriasis or World Psoriasis Day. CONCLUSION: This study highlights the need for increased education and awareness about psoriasis to address misunderstandings and reduce the burden of the condition on patients. Additionally, efforts are needed to reduce stigma and discrimination towards those with psoriasis, which can significantly impact their quality of life.

5.
Cureus ; 15(11): e48731, 2023 Nov.
Article in English | MEDLINE | ID: mdl-38094545

ABSTRACT

BACKGROUND: Vitamin D, zinc, and ferritin deficiencies are prevalent worldwide and linked to various health outcomes, including hair loss. This study aimed to assess the knowledge, attitude, and practices related to these deficiencies among citizens in Jazan, Saudi Arabia, and their perceptions regarding the relationship between these deficiencies and hair loss. METHODS: A cross-sectional study using a self-administered questionnaire was conducted between May 2023 and July 2023 among 985 participants, predominantly young adults aged between 18 and 25 years (58.9%, n = 580), females (56.2%, n = 554), single individuals (65.2%, n = 642), and Saudi citizens (98.2%, n = 967). Information on participants' demographics, knowledge, and practices related to vitamin D, zinc, and ferritin deficiencies was collected through Google Forms (Alphabet Inc., Mountain View, CA, USA). Knowledge levels were categorized as high or low based on responses. RESULTS: Almost all participants (95.2%, n = 938) had heard about vitamin D, zinc, and ferritin deficiencies and their risk of hair loss, and 554 (56.2%) participants had high knowledge, whereas 431 (43.8%) had low knowledge. The majority used the Internet to get information (37.1%, n = 365), identified sunlight as a source of these vitamins and minerals (91.7%, n = 903), and believed in their association with hair loss (74.0%, n = 729). Only about a third of participants reported daily sun exposure of 34.9% (n = 344) and vitamin supplement use of 35.4% (n = 349). Regression analysis revealed gender, awareness of vitamins, and vitamin supplement intake as significant factors related to hair loss (p < 0.001). CONCLUSIONS: The findings underscore the need for health education to improve sun exposure and supplement use practices, which could potentially reduce the prevalence of these deficiencies and associated hair loss. Future research should consider exploring other factors influencing hair loss and extending the study to different demographic groups.

6.
J Popul Ther Clin Pharmacol ; 29(4): e69-e82, 2022.
Article in English | MEDLINE | ID: mdl-36414571

ABSTRACT

This review aims to report the current literature on the status of ferrule in root-filled teeth, classify the different types of ferrules, highlight the biomechanical failures due to inadequate ferrule effect, and discuss the current restorative concepts according to the ferrule design principles.


Subject(s)
Post and Core Technique , Tooth, Nonvital , Humans , Dentistry
7.
Article in English | MEDLINE | ID: mdl-34205637

ABSTRACT

AIMS: Due to the continuous changes in modern lifestyle and the need to explore the effect of these changes on the risk of developing cancer, ongoing research on the epidemiology and characteristics of cancer patients is requested. This study explored the epidemiology of cancer, its characteristics, treatment patterns, and risk factors in the southern region of Saudi Arabia. METHODS: A retrospective cross-sectional study was conducted using cancer patients' medical records at Asir Central Hospital in the southern region of Saudi Arabia. Active patients' records were extracted between January 2013 and December 2019. RESULTS: A total of 2038 patients were identified during the study period, with a mean age of 60.9 (SD: 19.0) years. The patients had survived with their cancer for a median duration of 4 years (IQR: 2-6). Around 4.6% of the patients required ICU admission with a median period of 9 days (IQR: 5-14.75). The death rate during the study period was 10.9%. Around 20.8% of the cases were metastatic, of which 77.8% were at stage four of metastasis, and 19.7% of the patients were receiving chemotherapy for their disease. The most common types of cancer were malignant neoplasms of digestive organs, comprising 40.8% of the sample. Older age (60 years and above) and using specific chronic disease medications were predictors associated with a higher risk of death due to cancer (p < 0.05). Smoking history, using specific chronic disease medications, and having previous surgery were predictors associated with a higher risk of ICU admission (p < 0.05). CONCLUSION: Breast, colon, and liver cancers were the most prevalent in the southern region of Saudi Arabia. Several modifiable cancer risk factors were identified. The results of this study should support decision-makers in the initiation of programs for key modifiable risk factors that enhance lifestyle changes and reduce cancer risks.


Subject(s)
Neoplasms , Aged , Cross-Sectional Studies , Humans , Middle Aged , Neoplasms/epidemiology , Neoplasms/therapy , Retrospective Studies , Risk Factors , Saudi Arabia/epidemiology
8.
Cureus ; 11(10): e6013, 2019 Oct 28.
Article in English | MEDLINE | ID: mdl-31815077

ABSTRACT

Atypical mycobacterioses are unusual infections of the skin and other organs caused by non-tuberculous mycobacteria. Fish tank granuloma and swimming pool granuloma are two forms of atypical mycobacterioses caused by Mycobacterium marinum. So far, only a few cases of these infections have been reported in organ transplant patients, and these usually are more severe when compared with atypical mycobacterioses in immunocompetent hosts. We report a kidney transplant patient with a rather mild form of atypical mycobacteriosis (fish tank granuloma) who responded well to treatment with doxycycline and will provide a review of all similar cases reported in the literature.

9.
J Forensic Dent Sci ; 4(2): 63-5, 2012 Jul.
Article in English | MEDLINE | ID: mdl-23741143

ABSTRACT

OBJECTIVE: To estimate the age of an individual between 13 and 23 years, using Demirjian method in Saudi male patients in the southern region of the Kingdom of Saudi Arabia. MATERIALS AND METHODS: A total of 360 male patient's digital panoramic radiographs were used to evaluate the morphology of mandibular 3rd molar teeth roots according to the Demirjian method. Using descriptive statistical method, age was calculated. RESULTS: Result showed a strong relation of age with stages of root development of 3rd molar teeth. The standard deviation of mean of root development stages is 1.47 years of age. CONCLUSION: This study suggests that age can be predicted with a statistical significant result for ages between 13 and 23. Further studies with large population are needed for better statistical results and for female age assessment.

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