1.
Asian Pacific Journal of Tropical Biomedicine
; (12): 921-927, 2015.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-950984
ABSTRACT
Objective: To evaluate the scientific basis for the use of Kang 601 heji (K-601) as an anti-inflammatory and antipyretic agent using appropriate animal models. Methods: Carrageenan-induced rat paw and xylene-induced ear oedemas were models used to investigate anti-inflammatory actions of K-601. Lipopolysaccharide-induced pyrexia model was used to evaluate antipyretic activity in Wistar rats. The anti-inflammatory and antipyretic mechanisms were evaluated by detecting prostaglandins E