ABSTRACT
The method of intravital fluorescence microscopy was used to study permeability by sodium fluoresceine of the structural components of the rat liver 7,21 and 60 days after bilateral subphrenic vagotomy. It was found that vagotomy resulted in a permeability rise both of the liver microvessels and hepatocyte plasma membranes. Later the temporal indices return to the initial levels.
Subject(s)
Liver/blood supply , Vagus Nerve/physiology , Animals , Capillary Permeability , Male , Rats , VagotomySubject(s)
Embryology/history , Histology/history , Schools, Medical/history , History, 20th Century , MoscowABSTRACT
The authors studied the 24-hour variations of mitoses in the stellate reticuloendothelial intralobular blood capillaries of rats under normal conditions and after bilateral subphrenic vagotomy. The greatest number of mitoses was noted in all the animals in the morning hours--3 to 7 a.m. A gradual decrease in the number of mitoses occurred in vagotomized and laparotomized animals by 10 p.m. After vagotomy the number of mitoses in the stellate reticuloendotheliocytes and in hepatocytes was double that in control; the character of the curve reflecting the 24-hour periodicity of mitoses in denervated liver was unchanged in comparison with control.