[Prolonged venovenous hemofiltration in intensive care of children with severe thermal injury].

The efficiency of using prolonged venovenous hemofiltration (PVVH) was studied in 12 children with severe thermal injury in the presence of multiple organ dysfunctions. All the children were critically ill (having artificial ventilation, inotropic support, states of coma, renal dysfunction) and received the whole package of intensive care measures. Five of the 12 children were diagnosed as having sepsis, as verified by the procalcitonin ( >10 ng/ml) test. All the patients received 2 to 10 sessions PVVH on a PRIZMA apparatus ("Gambra", Sweden). Five of the 12 children died; the remaining children were observed to feel better; they were all transferred to somatic units. Thus, PWVVH is the method of choice in complex therapy for severe thermal injury followed by the development of multiple organ dysfunctions.

[Oxygen delivery, consumption and extraction in the acute period of burns in children]. / Dostavka, potreblenie i ékstraktsiia O2 v ostryi period ozhogovoi bolezni u detei.

Eighty-six children with burn injuries hospitalized in intensive care wards during the acute period of burn disease were examined. They were divided into 3 groups: with involvement of up to 30%, 31-60%, and more than 61% of body surface. The children were examined during and after shock. The study was aimed at investigating the delivery, consumption, and extraction of oxygen in order to assess the criteria of disorders in the blood gas transporting system. In group 1 these parameters were higher than normally during the acute period, reflecting the adequate reaction to burn injury. Therapeutic measures required volume support with infusion media. In the second and third groups these parameters were increased both during and after shock; for increasing oxygen transport, inotropic support was administered. In the third group oxygen delivery was within the norm which did not correspond to its consumption and, hence, respiratory support was needed.