ABSTRACT
Fibrohistiocytomas are soft tissue tumors of histiocytic origin that have a variety of histological patterns. Although cases of malignant fibrous histiocytoma (MFH) of the head and neck have been reported with increasing frequency in recent years, they are considered rare. We report a case of the giant cell variant of MFH of the neck in which the patient had been given radiotherapy for T1 glottic cancer. Prognosis of MFH, the use of radiation as primary treatment, and its role in the development of secondary primary tumors in the head and neck region are reviewed. [Editorial comment: The authors stress the important relationship between prior radiation therapy and the induction of new tumors.]
Subject(s)
Carcinoma, Squamous Cell/radiotherapy , Head and Neck Neoplasms/etiology , Head and Neck Neoplasms/secondary , Histiocytoma, Benign Fibrous/etiology , Histiocytoma, Benign Fibrous/secondary , Laryngeal Neoplasms/radiotherapy , Neoplasms, Radiation-Induced/etiology , Neoplasms, Radiation-Induced/secondary , Neoplasms, Second Primary/diagnosis , Neoplasms, Second Primary/therapy , Humans , Male , Middle AgedABSTRACT
PURPOSE: To report a 2 1/2-year-old boy who had papillary adenocarcinoma of the ciliary body that simulated retinoblastoma. METHOD: Initially treated for congenital glaucoma, the patient was referred with a white mass involving the iris, chamber angle, and ciliary body. RESULTS: Enucleation of the right eye, which was initially diagnosed as retinoblastoma, showed a papillary adenocarcinoma of the ciliary body epithelium involving the posterior chamber, iris, anterior chamber, and trabeculum. CONCLUSION: Adenocarcinoma of the ciliary body must be included in the differential diagnosis of tumors originating from the ciliary body in young children.
