ABSTRACT
INTRODUCTION: Composite running-specific prostheses (RSP) are widely used by athletes with lower limb amputations to simulate the spring-like behavior of biological legs. However, the effect of these devices on the biomechanics of athletes with transtibial amputations remains uncertain. MODELING METHOD DESCRIPTION: To address this issue, this study proposes a time-dependent finite element model that uses angles and dynamic loads during ground contact to evaluate RSP performance parameters such as stiffness and energy efficiency. The study also examines the impact of running speed and RSP geometry on performance. NUMERICAL SIMULATION AND MODEL VERIFICATION: The in-silico characterization approach used in this study takes into account both the intrinsic characteristics of the RSP and the athlete's biomechanics to identify the influence of fundamental geometric variables of the RSP on performance. The model is verified by comparing its results with experimental data. RESULTS AND DISCUSSION: The study found that as running speed increases, RSP stiffness, vertical ground reaction force (vGRF), and contact time decrease. The force-displacement profiles of RSP are nonlinear, but a linear function can be used to accurately represent their behavior at high sprinting speeds. Using higher RSP reduces energy efficiency and vGRF due to their lower stiffness. J-curve RSP result in higher stiffness, vGRF, and strain energy, while C-curve RSP are associated with longer contact times and higher energy efficiency.
ABSTRACT
The fallopian tube (FT) plays a crucial role in the reproductive process by providing an ideal biomechanical and biochemical environment for fertilization and early embryo development. Despite its importance, the biomechanical functions of the FT that originate from its morphological aspects, and ultrastructural aspects, as well as the mechanical properties of FT, have not been studied nor used sufficiently, which limits the understanding of fertilization, mechanotrasduction, and mechanobiology during embryo development, as well as the replication of the FT in laboratory settings for infertility treatments. This paper reviews and revives valuable information on human FT reported in medical literature in the past five decades relevant to the biomechanical aspects of FT. In this review, we summarized the current state of knowledge concerning the morphological, ultrastructural aspects, and mechanical properties of the human FT. We also investigate the potential arising from a thorough consideration of the biomechanical functions and exploring often neglected mechanical aspects. Our investigation encompasses both macroscopic measurements (such as length, diameter, and thickness) and microscopic measurements (including the height of epithelial cells, the percentage of ciliated cells, cilia structure, and ciliary beat frequency). Our primary focus has been on healthy women of reproductive age. We have examined various measurement techniques, encompassing conventional metrology, 2D histological data as well as new spatial measurement techniques such as micro-CT.
