Subject(s)
Bimatoprost/adverse effects , Hyperpigmentation/chemically induced , Iris/drug effects , Administration, Topical , Antihypertensive Agents/administration & dosage , Antihypertensive Agents/adverse effects , Bimatoprost/administration & dosage , Eyelashes/drug effects , Female , Humans , Middle Aged , Ophthalmic SolutionsABSTRACT
Fibrofolliculoma and trichodiscoma are adnexal tumors that arise from or around hair follicles and are two of the many characteristic features of Birt-Hogg-Dubé (BHD) syndrome. Fibrofolliculoma and other hair follicle hamartomas can be differentiated from their clinically indistinct counterparts (eg, trichodiscomas, trichoadenomas) by histologic and staining comparison. We report a rare case of a 54-year-old man who presented with a subcutaneous papule on the abdomen that was histologically proven to have features of both a solitary fibrofolliculoma and trichodiscoma.
Subject(s)
Fibroma/diagnosis , Hair Follicle , Hamartoma/diagnosis , Neoplasms, Multiple Primary/diagnosis , Skin Neoplasms/diagnosis , Abdomen , Diagnosis, Differential , Fibroma/complications , Fibroma/pathology , Hamartoma/complications , Hamartoma/pathology , Humans , Male , Middle Aged , Neoplasms, Multiple Primary/complications , Neoplasms, Multiple Primary/pathology , Skin Neoplasms/complications , Skin Neoplasms/pathologyABSTRACT
Primary cutaneous diffuse large B-cell lymphoma, leg type (DLBCLLT) is a rare, intermediately aggressive form of primary cutaneous B-cell lymphoma (CBCL) that is characterized by the presence of large round cells on histopathology. Clinically, patients present with red-brown nodules on the distal legs. The prognosis is less favorable than other types of CBCLs, with a 5-year survival rate of 50%. We present a case of primary cutaneous DLBCLLT in a 74-year-old woman. A comprehensive review of cutaneous T-cell lymphoma and CBCL also is provided, along with a discussion of the T-cell and B-cell forms of pseudolymphoma.
Subject(s)
Lymphoma, Large B-Cell, Diffuse/drug therapy , Lymphoma, Large B-Cell, Diffuse/pathology , Aged , Female , Humans , Leg/pathology , Lymphoma, Large B-Cell, Diffuse/diagnosis , PrognosisABSTRACT
BACKGROUND: Epidermal nevus syndrome is a multi-system disease with a wide spectrum of clinical presentation. Numerous specialists may be required to address its extra cutaneous manifestations. MAIN OBSERVATIONS: We report a severe case of epidermal nevus syndrome involving the oral cavity, pharynx, and central nervous system in addition to disfiguring skin lesions. CONCLUSIONS: Dermatologists are in a unique position to first render the diagnosis of epidermal nevus syndrome for young patients and ensure appropriate follow-up.
