ABSTRACT
Dystonia is a movement disorder characterized by sustained muscle contractions, causing twisting and repetitive movements or abnormal postures of affected body parts. Here, we present a novel case of focal dystonia of a 51 years old right-handed woman who had developed difficulty in writing and performing fine motor tasks. Due to a discomfort in her right hand at use, she started using her left hand instead and noticed inconsistent mirror movements in her right hand upon use of left hand. She was treated with trihexyphenidyl which allowed her right hand to function better, though writing still remained a problem.
Subject(s)
Dystonic Disorders/drug therapy , Hand/physiopathology , Trihexyphenidyl/therapeutic use , Dystonic Disorders/etiology , Female , Humans , Middle Aged , Treatment OutcomeABSTRACT
BACKGROUND: Many patients with restless legs syndrome (RLS) and Parkinson's disease (PD) report having pain, however, the impact of the combination of PD and RLS on pain has not been analyzed extensively. The objective of this study was to explore the potential relationship between RLS and pain in individuals with and without PD, the prevalence of RLS in PD, the prevalence and severity of pain in PD and RLS, and how these measures are related to PD patients and controls. METHODS: The study included 127 PD patients and an equal number of non-PD patients who were assessed for pain and RLS-like symptoms by using RLS diagnostic survey, RLS rating scale and Brief Pain Inventory. RESULTS: The results showed that 21.3% of PD patients had RLS, compared to only 4.7% in the control group, representing a highly significant difference (p<0.005). The frequency of reporting pain was also significantly higher among PD patients with RLS (p<0.005), but not in control group. However, the mean difference in average pain severity was not significantly different between the PD with RLS and non-PD with RLS, nor was the pain level and severity significantly correlated with RLS severity for either group. CONCLUSION: The presence of pain in PD patients may be exacerbated by RLS or in RLS patients, having PD may exacerbate pain.
Subject(s)
Pain/diagnosis , Pain/epidemiology , Parkinson Disease/diagnosis , Parkinson Disease/epidemiology , Restless Legs Syndrome/diagnosis , Restless Legs Syndrome/epidemiology , Aged , Aged, 80 and over , Female , Follow-Up Studies , Humans , Male , Middle Aged , Pain Measurement/methodsABSTRACT
Parkinson's disease (PD) is a neurodegenerative illness characterized by various non-motor symptoms that may contribute to disability, impaired quality of life and shortened life expectancy. The aim of present study was to determine the relative prevalence of common non-motor symptoms in various ethnic groups. A retrospective chart analysis was performed on Parkinson's disease patients where a total of 314 PD patients from six ethnic categories were examined for the occurrence of anxiety, visual hallucinations, nocturia, drooling and dementia. Our results show that anxiety in PD patients was correlated with their ethnicity classification. Interesting trends were observed with respect to nocturia and dementia symptoms and no significant differences were found between ethnic groups for visual hallucinations and drooling. Our study shows that non-motor symptoms of Parkinson's disease are prevalent across all ethnic groups, and except anxiety there may not be any impact of ethnicity on dementia, nocturia, drooling, and visual hallucinations.
