ABSTRACT
Malaria es una enfermedad de importancia en todo el mundo por su elevada morbimortalidad. Habiendo sido erradicada de Chile hace más de 50 año, se enfatizan sus aspectos biológicos, clínicos y terapéuticos para favorecer un reconocimiento oportuno y correcto manejo de los casos importados de la enfermedad
Subject(s)
Humans , Malaria/etiology , Plasmodium falciparum/pathogenicity , Plasmodium vivax/pathogenicity , Antimalarials/therapeutic use , Insect Vectors , Malaria/diagnosis , Malaria/drug therapy , Malaria/prevention & control , Mosquito Control , Plasmodium falciparum/growth & development , Plasmodium vivax/growth & development , Primary Prevention , Host-Parasite InteractionsABSTRACT
The performance of double-diffusion reaction on agar with arc 5 detection (DD5) in the diagnosis of hydatidosis in man is analyzed in this study. A review was made of the clinical histories of 226 patients who had been seen between 1980 and 1986 at a hospital in Santiago, Chile, with manifestations suggestive of this disease. In 98 cases the diagnosis of hydatidosis was confirmed surgically. In 55 of these cases (56.1 per cent), the DD5 was positive. The test was least sensitive for pulmonary hydatidosis (36 per cent), while the reaction was positive for 62.7 per cent of the patients with a single cyst of multiple liver cysts, and for 64.7 per cent of those who had hydatid cysts in more than one organ. In the 128 non-hydatid patients who had neoplasms, benign tumors, cirrhosis of the liver, or other diseases, no false positive results were observed when the criterion for positivity was either the presence of arc 5 or of three or more precipitation bands. According to the results of this study, the use of DD5 for the diagnosis of hydatidosis in clinically selected individuals provides a highly specific test. The positive predictive value of the test in the study was 99.1 per cent. It should also be noted, however, that negative results with DD5 do not invalidate the presence of hydatid cysts in a patient especially in pulmonary cases
Subject(s)
Bacteriological Techniques , Echinococcosis/diagnosis , AgarABSTRACT
Se investiga el riesgo de la transmisión de la enfermedad de Chagas por transfusión sanguínea, mediante una encuesta serológica de muestras de donantes de sangre en diversos hospitales en la zona de endemia chagásica en Chile (AU)
Subject(s)
Trypanosoma cruzi/isolation & purification , Chagas Disease/transmission , Blood Banks , Cross Infection/epidemiology , Chile/epidemiology , Blood Transfusion/adverse effectsABSTRACT
Se investiga el riesgo de la transmision de la enfermedad de Chagas por transfusion sanguinea, mediante una encuesta serologica de muestras de donantes de sangre en diversos hospitales en la zona de endemia chagasica en Chile
Subject(s)
Chagas Disease/transmission , Trypanosoma cruzi/isolation & purification , Blood Banks , Chile/epidemiology , Cross Infection/epidemiology , Blood Transfusion/adverse effectsSubject(s)
Blood/parasitology , Blood Banks , Trypanosoma cruzi/isolation & purification , Risk , ChileABSTRACT
The performance of double-diffusion reaction on agar with arc 5 detection (DD5) in the diagnosis of hydatidosis in man is analyzed in this study. A review was made of the clinical histories of 226 patients who had been seen between 1980 and 1986 at a hospital in Santiago, Chile, with manifestations suggestive of this disease. In 98 cases the diagnosis of hydatidosis was confirmed surgically. In 55 of these cases (56.1 per cent), the DD5 was positive. The test was least sensitive for pulmonary hydatidosis (36 per cent), while the reaction was positive for 62.7 per cent of the patients with a single cyst of multiple liver cysts, and for 64.7 per cent of those who had hydatid cysts in more than one organ. In the 128 non-hydatid patients who had neoplasms, benign tumors, cirrhosis of the liver, or other diseases, no false positive results were observed when the criterion for positivity was either the presence of arc 5 or of three or more precipitation bands. According to the results of this study, the use of DD5 for the diagnosis of hydatidosis in clinically selected individuals provides a highly specific test. The positive predictive value of the test in the study was 99.1 per cent. It should also be noted, however, that negative results with DD5 do not invalidate the presence of hydatid cysts in a patient especially in pulmonary cases
Subject(s)
Echinococcosis , Bacteriological Techniques , AgarABSTRACT
Se investiga el riesgo de la transmisión de la enfermedad de Chagas por transfusión sanguínea, mediante una encuesta serológica de muestras de donantes de sangre en diversos hospitales en la zona de endemia chagásica en Chile (AU)
