A chemosensor showing discriminating fluorescent response for highly selective and nanomolar detection of Cu²âº and Zn²âº and its application in molecular logic gate.

A fluorescent based receptor (4Z)-4-(4-diethylamino)-2-hydroxybenzylidene amino)-1,2dihydro-1,5-dimethyl-2-phenylpyrazol-3-one (receptor 3) was developed for the highly selective and sensitive detection of Cu(2+) and Zn(2+) in semi-aqueous system. The fluorescence of receptor 3 was enhanced and quenched, respectively, with the addition of Zn(2+) and Cu(2+) ions over other surveyed cations. The receptor formed host-guest complexes in 1:1 stoichiometry with the detection limit of 5 nM and 15 nM for Cu(2+) and Zn(2+) ions, respectively. Further, we have effectively utilized the two metal ions (Cu(2+) and Zn(2+)) as chemical inputs for the manufacture of INHIBIT type logic gate at molecular level using the fluorescence responses of receptor 3 at 450 nm.

Design and Synthesis of a Pyridine Based Chemosensor: Highly Selective Fluorescent Probe For Pb2+

A pyridine based imine-linked chemosensor has been synthesized and evaluated its binding affinity with library of transition metal ions. It has prominent selectivity towards Pb2+ among other metal ions in DMF/H2O (9:1, v/v) solvent system. The 1:1 stoichiometric was confirmed by job's plot and has a binding constant (Ka) = 5.142 × 103 M-1 on fluorescence. A B3LYP/6-31G and B3LYP/LanL2DZ basis sets were employed for optimization of 3 and 3.Pb2+.

Monitoring and respiratory health assessment of the population exposed to cooking fuel emissions in a rural area of Jalgaon district, India.

Indoor air pollution is an ongoing problem in developing countries. Respiratory diseases are common worldwide in rural communities. This study was undertaken to estimate the respirable particulate matter (PM10) concentrations emitted from cooking fuels and their effects on the respiratory health of the rural population of Jalgaon district. The respiratory status of the exposed population was assessed by conducting pulmonary function tests in the study area. The levels of forced vital capacity and forced expiratory volume in 1 second were lower, and difficulty in respiration and frequent coughing were more common with higher odds ratios (OR) of 2.53 (95% confidence interval [CI] = 1.1-2.83) and 1.84 (95% CI = 0.95-2.10) in agrowaste-user female subjects. Ventilatory impairment among the agrowaste-user subjects was higher than among users of gas and wood. Difficulty in respiration and frequent coughing were strongly associated in wood-user female subjects as well with ORs of 2.10 (95% CI = 0.85-2.49) and 1.79 (95% CI = 0.91-1.98), respectively. Chest pain was significantly associated in agrowaste- and wood-user female subjects. This study confirms an association between the reductions in lung efficiency with high PM10 exposure in the rural population. The result of this study reveals an association between respiratory diseases symptoms and indoor air quality in the biomass-using rural population of Jalgaon district.

The influence of workplace environment on lung function of flour mill workers in Jalgaon urban center.

The workplace environment affects the health of workers. Unhygienic conditions are observed in the workplace environment of flour mills as fine organic flour dust gets airborne in the indoor environment of the flour mills. The present work was undertaken to study the health problems related to the workplace environment of flour mill workers. The results show that flour mill workers are receiving a heavy dose (average exposure concentration, 624 microg/m3) of flour dust. To determine the impact of flour dust on the lung function of the workers spirometric analysis was conducted. Significant declines in forced vital capacity (FVC), peak expiratory flow rate (PEFR) and forced expiratory volume in one second (FEV1) were observed in the flour mill workers as compared to expected values. This study reveals reduced lung efficiency of flour mill workers due to excessive exposure to fine organic dust prevalent in the workplace environment. The impairment in lung efficiency was increased with duration of exposure in the flour mill workers. The analysis of questionnaires used to generate information on self-reported problems reveals that most of the workers were suffering from asthma and respiratory problems. Furthermore, the data shows that 42% of the flour mill workers were having shortness of breath problems, 34% of workers were having frequent coughing, and 19% workers were having respiratory tract irritation. We recommend the compulsory use of personal protective equipment (nose mask) by flour mill workers during working hours. This would help to protect the workers health from the flour dust prevalent in the workplace environment. A regular periodic examination is necessary to measure the impact of particulate matter on the health of the flour mill workers.

Exposure to vehicular pollution and respiratory impairment of traffic policemen in Jalgaon City, India.

The ambient air quality monitoring was carried during the May 2003 to April 2004 along the (NH-6) passing through Jalgaon city. The average concentration of SOx 64 microg/m3, NOx 58 microg/ m3, particulates (> 10 micro) 515 microg/m3 and respirable dust particulates 224 microg/m3 was reported at Prabhat during the study period (May 2003-April 2004). This location represents the major highway crossings (four) in the study area. The present investigations are on the survey of health status and lung function of traffic policemen exposed to the inferior air quality as observed on the highway crossings. The spirometric analysis of traffic policemen shows significant variation in Peak Expiratory Flow Rate (PEFR), Forced Expiratory Volume in one second (FEV1) and Forced Vital Capacity (FVC). The parameters were significantly affected in the traffic policemen as against the control group of population. It reveals significant respiratory impairment in the traffic policemen due to exposure to vehicular pollution. The study suggest the compulsory use of personal protective equipment (nose mask) by the traffic policemen during duty hours will help for the protection from vehicular pollution. The regular periodic health checkup is required to understand the impact of vehicular pollution on the health of traffic policemen.

Ecofriendly approach of urban solid waste management: a case study of Jalgaon city, Maharashtra.

In India, the traditional methods are used for urban solid waste management. These practices are associated with degradation of the urban environment Hence, an environmentally sound garbage management system is required for the urban waste management. The concept of waste minimization needs to be adopted in such systems. It is possible to implement certain corrective measures at collection, storage, transport and disposal of urban solid waste to minimize the adverse impacts on the environment The present investigations are emphasized on generation, characterzation and ecofriendly disposal of solid waste generated in Jalgaon city, Maharashtra. In the present study the waste generation at source was studied in the various income groups of the city. The per capita waste generation was studied by sampling the waste directly from the source of generation. The study reveals that the waste generation is large in the high-income group followed by middle and low-income group public. Further the physicochemical characterization of the waste was also studied. The data generated will help to develop environmentally sound and economically feasible solid waste management system for Ihe city.