ABSTRACT
INTRODUCTION: Myxofibrosarcoma of the thyroid is exceptional: a Medline search found a single case report. We report a new case which raised diagnostic and therapeutic problems. OBSERVATION: We report the case of a 74-year-old woman who presented with swelling of the left thyroid lobe and ipsilateral cervical lymphadenopathy. Total thyroidectomy with cervical lymph-node dissection was performed. Histological analysis diagnosed myxofibrosarcoma. Evolution was marked by rapid local recurrence, and chemotherapy based on doxorubicin and ifosfamide was introduced. DISCUSSION/CONCLUSION: Head and neck myxofibrosarcoma is rare. MRI is essential and should always precede treatment. Diagnosis is histological. There is elevated risk of local recurrence after resection, accompanied by worsening tumor grade, whence the need for accurate diagnosis, appropriate treatment and regular MRI follow-up.
Subject(s)
Fibrosarcoma/pathology , Thyroid Neoplasms/pathology , Aged , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Doxorubicin/administration & dosage , Female , Fibrosarcoma/therapy , Humans , Ifosfamide/administration & dosage , Lymph Node Excision , Neoplasm Recurrence, Local , Thyroid Neoplasms/therapy , ThyroidectomyABSTRACT
Tuberculous of the oral cavity is rare, the attack tonsil remains exceptional. We report case a 25-year-old young male, who consults for an ulceration of the left unilateral tonsil, with a homolateral adenopathy jugulo-carotidien. The examination anatomopathologic of the tonsil biopsy revealed a tuberculous of the tonsil. The patient profited from an antituberculous treatment, the evolution was good.