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Ir Med J ; 111(9): 826, 2018 10 11.
Article in English | MEDLINE | ID: mdl-30556674

ABSTRACT

Introduction Merkel cell carcinoma (MCC) is a rare cutaneous tumour that is clinically aggressive with a high local, regional, and distant metastatic potential. Cases Three male patients presented to University Hospital Limerick (UHL) in 2015 with cutaneous lesions of the thorax, buttock and forearm. Once MCC was confirmed, management included surgical wide local excision (WLE) with regional lymph node dissection followed by adjuvant radiotherapy. One patient is in remission. The second has residual locoregional lymph node disease and is undergoing annual CT surveillance. The third had distant metastatic disease and is deceased from an unrelated condition. Discussion This case series highlights the presentation and management of MCC. We also discus relevant guidelines. The management of MCC is complex and there is a need to establish local or national databases to identify and monitor patients with MCC.


Subject(s)
Carcinoma, Merkel Cell/pathology , Carcinoma, Merkel Cell/therapy , Dermatologic Surgical Procedures/methods , Skin Neoplasms/pathology , Skin Neoplasms/therapy , Aged , Carcinoma, Merkel Cell/diagnostic imaging , Combined Modality Therapy , Fatal Outcome , Humans , Lymph Node Excision , Male , Middle Aged , Practice Guidelines as Topic , Radiotherapy, Adjuvant , Skin Neoplasms/diagnostic imaging , Tomography, X-Ray Computed , Treatment Outcome
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