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J Fr Ophtalmol
; 44(7): e423-e427, 2021 Sep.
Article
in French
| MEDLINE
| ID: mdl-33832753
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J Fr Ophtalmol
; 42(1): e15-e17, 2019 Jan.
Article
in French
| MEDLINE
| ID: mdl-30545679
3.
J Fr Ophtalmol
; 41(3): 262-270, 2018 Mar.
Article
in French
| MEDLINE
| ID: mdl-29573862
ABSTRACT
All the components of the ocular surface and the lacrimal system are affected by aging. Aging induces lacrimal gland fibrosis, Meibomian gland dysfunction, loss of corneal sensitivity, decreased corneal cell density, impairment of immune defences, increased local inflammation associated with hormonal changes, conjunctivochalasis, lid abnormalities, etc. Furthermore, homeostasis of the ocular surface may be altered by various age-related systemic comorbidities and iatrogenic interventions. Altogether, aging is considered the most predominant risk factor for dry eye disease. The increasing knowledge of the pathophysiology of aging of the ocular surface allows for refinement of the management of ocular surface disease in the elderly.