1.
Clin Pediatr (Phila)
; 14(4): 355-7/362-8, 1975 Apr.
Article
in English
| MEDLINE
| ID: mdl-164311
ABSTRACT
A high percentage of Greek children with homozygous b-thalassemia were short and had a lag in growth, though some severely affected attained normal height. Bone age lagged significantly behind the chronologic age, even in those with normal height for their age. A longitudinal study demonstrated an initial normal growth velocity which decreased after the age of six for males and eight for females. No patient had a spurt of growth at adolescence. Height gain continued up to the age of 21 and then ceased. Statistical analysis with a multiple regression equation showed a significant relationship between the age and height of the patients. Low hemoglobin levels and severity of the disease seemed to hinder normal growth, but neither relationship was statistically significant.
Subject(s)
Body Height , Growth Disorders/etiology , Thalassemia/complications , Adolescent , Adult , Age Determination by Skeleton , Age Factors , Child , Child, Preschool , Female , Greece , Hemoglobins/analysis , Homozygote , Humans , Infant , Male , Regression Analysis , Thalassemia/blood , Thalassemia/physiopathology
2.
Pediatrics
; 50(1): 92-9, 1972 Jul.
Article
in English
| MEDLINE
| ID: mdl-5038114
Subject(s)
Growth , Thalassemia/physiopathology , Adolescent , Adult , Age Factors , Body Height , Body Weight , Cephalometry , Child , Child, Preschool , Craniofacial Dysostosis/etiology , Female , Greece , Growth Disorders/etiology , Hemoglobins/analysis , Hepatomegaly/etiology , Humans , Intelligence , Male , Skull/abnormalities , Splenectomy/adverse effects , Splenomegaly/etiology , Syndrome , Thalassemia/complications
3.
Neurology
; 22(3): 294-304, 1972 Mar.
Article
in English
| MEDLINE
| ID: mdl-5062264
Subject(s)
Muscular Diseases/etiology , Neurologic Manifestations , Thalassemia/complications , Adolescent , Adult , Blood Transfusion , Cerebrovascular Disorders/etiology , Child , Child, Preschool , Deafness/etiology , Electroencephalography , Electromyography , Female , Growth , Headache/etiology , Hemoglobinometry , Hepatomegaly/etiology , Humans , Intelligence , Ischemic Attack, Transient/etiology , Male , Paralysis/etiology , Seizures/etiology
4.
Pediatrics
; 48(5): 740-4, 1971 Nov.
Article
in English
| MEDLINE
| ID: mdl-5121236
Subject(s)
Behavior , Intelligence , Thalassemia/complications , Adolescent , Adult , Affective Symptoms/etiology , Anxiety/etiology , Blood Transfusion , Child , Child, Preschool , Chronic Disease , Depression/etiology , Female , Homozygote , Humans , Intelligence Tests , Male , Personality Disorders/etiology , Psychometrics , Thalassemia/therapy
5.
Am J Dis Child
; 121(4): 300-6, 1971 Apr.
Article
in English
| MEDLINE
| ID: mdl-5550735
Subject(s)
Bone Diseases, Developmental/etiology , Facial Bones/abnormalities , Skull , Thalassemia/complications , Adolescent , Age Factors , Blood Transfusion , Bone Diseases, Developmental/classification , Bone Diseases, Developmental/diagnostic imaging , Cephalometry , Child , Child, Preschool , Female , Fractures, Bone/complications , Hemoglobins , Homozygote , Humans , Intelligence , Intelligence Tests , Jaw Abnormalities/etiology , Liver/physiopathology , Liver Function Tests , Male , Malocclusion/etiology , Radiography , Sex Factors , Splenectomy , Thalassemia/physiopathology , Thalassemia/therapy , Time Factors
6.
Vox Sang
; 20(3): 252-8, 1971 Mar.
Article
in English
| MEDLINE
| ID: mdl-4106065
Subject(s)
Antibodies/analysis , Blood Transfusion , Epitopes , Thalassemia/immunology , Adolescent , Adult , Antibody Formation , Antibody Specificity , Antigens , Blood Group Antigens , Blood Platelets/immunology , Child , Child, Preschool , Complement Fixation Tests , Coombs Test , Cytotoxicity Tests, Immunologic , Edetic Acid , Greece , Hemagglutination Tests , Homozygote , Humans , Isoantibodies/analysis , Leukocytes/immunology , Splenectomy
7.
Acta Haematol
; 42(6): 321-9, 1969.
Article
in English
| MEDLINE
| ID: mdl-4986099
8.
Bibl Haematol
; 29: 494-500, 1968.
Article
in English
| MEDLINE
| ID: mdl-5727706
